Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   EHW89_RS01915 Genome accession   NZ_CP034543
Coordinates   377265..379142 (+) Length   625 a.a.
NCBI ID   WP_126466518.1    Uniprot ID   -
Organism   Streptococcus periodonticum strain KCOM 2412     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 372265..384142
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EHW89_RS01900 (EHW89_01900) fmt 374271..375206 (+) 936 WP_126466516.1 methionyl-tRNA formyltransferase -
  EHW89_RS01905 (EHW89_01905) rsmB 375196..376509 (+) 1314 WP_126466517.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  EHW89_RS01910 (EHW89_01910) - 376528..377268 (+) 741 WP_003025814.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  EHW89_RS01915 (EHW89_01915) stkP 377265..379142 (+) 1878 WP_126466518.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  EHW89_RS01920 (EHW89_01920) liaF 379403..380101 (+) 699 WP_126466519.1 cell wall-active antibiotics response protein LiaF -
  EHW89_RS01925 (EHW89_01925) - 380098..381093 (+) 996 WP_126466520.1 sensor histidine kinase -
  EHW89_RS01930 (EHW89_01930) - 381095..381727 (+) 633 WP_003043328.1 response regulator transcription factor -
  EHW89_RS01935 (EHW89_01935) - 381767..383167 (+) 1401 WP_126466521.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  EHW89_RS01940 (EHW89_01940) - 383169..383543 (+) 375 WP_003025803.1 S1 RNA-binding domain-containing protein -
  EHW89_RS01945 (EHW89_01945) - 383669..383986 (-) 318 WP_003031462.1 DUF960 domain-containing protein -

Sequence

Protein


Download         Length: 625 a.a.        Molecular weight: 67868.02 Da        Isoelectric Point: 9.4881

>NTDB_id=331765 EHW89_RS01915 WP_126466518.1 377265..379142(+) (stkP) [Streptococcus periodonticum strain KCOM 2412]
MIQVGKIFAGRYKIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEEGQQYLAMEYVAGLDLKRYIKEHAPLSNEEAVRIMGQILLAMRLAHTHGIVHRDLKPQNVLLTPDGDAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSIIAENPNVP
QALENVVIKATAKKLTDRYQSVAEMYVDLSSCLSADRRNEKKLVFDDTAKADTKTLPKVSQNTLTSASKPTTPTPIKEAV
SSKPTPKPKAKKKRRLRTRYKVLLSAVVLVIVALVALVYLSPSNVKIPDVTGKTIAQARSAIETAGLKVGKEKDEYSDSV
KKDSVIRTNPEAGTQRREGSTVDLIVSKGTKTFIMEDYKGQKRADAINNLVQKYKVSKGLIKTEEVESNEYAAGTVVDQT
PAAGSTYDLTSKTRITLKVAKSVSSVTMPSYIGSTYEFAYNNLTEVIGIQGANIEKRTVTTAPAGTQANTIIRQTPEAGQ
SLNLKSDRIVLYVYEPKNEDSSTSESSSQSDSSSNKTSPSSSSSSTSGNDGSSSKTPDTSASASN

Nucleotide


Download         Length: 1878 bp        

>NTDB_id=331765 EHW89_RS01915 WP_126466518.1 377265..379142(+) (stkP) [Streptococcus periodonticum strain KCOM 2412]
ATGATTCAAGTCGGCAAGATATTTGCCGGACGATATAAAATCATCAAACAAATTGGTCGAGGTGGCATGGCAGATGTCTA
CTTGGCGAAAGACTTGATTTTAGACGGGGAAGAAGTCGCAGTTAAGGTTCTAAGAACCAATTACCAGACGGATCCAATTG
CTGTAGCACGTTTTCAAAGAGAAGCACGCGCCATGGCAGACTTGGATCATCCTCATATTGTCCGGATTACCGACATTGGA
GAAGAAGAAGGTCAGCAGTATCTAGCAATGGAGTATGTGGCTGGACTTGACTTAAAACGCTATATCAAAGAGCATGCTCC
TTTGTCTAATGAAGAAGCGGTTCGAATCATGGGACAAATCCTTTTGGCGATGCGTTTGGCACACACGCATGGGATTGTTC
ACCGTGATTTGAAACCTCAAAATGTCCTTTTAACTCCAGATGGCGATGCAAAAGTAACAGACTTTGGGATTGCAGTAGCT
TTTGCAGAAACGAGTTTAACGCAAACCAACTCTATGTTGGGGTCTGTACATTATTTGTCACCAGAACAGGCGCGTGGCTC
AAAAGCGACCGTTCAGAGCGATATTTATGCCATGGGGATTATTTTCTATGAAATGCTGACAGGACATATCCCTTATGATG
GAGATAGTGCTGTTACGATTGCCCTACAACATTTCCAAAAGCCTCTACCGTCTATTATTGCTGAAAATCCAAATGTTCCA
CAGGCATTGGAAAATGTAGTCATCAAGGCAACGGCCAAAAAATTGACGGATCGTTATCAGTCAGTTGCAGAAATGTATGT
GGATTTATCAAGCTGCTTATCTGCTGACCGTCGAAATGAGAAAAAACTAGTTTTTGATGACACTGCTAAAGCAGACACCA
AGACGCTTCCTAAGGTATCGCAAAATACGTTAACTTCTGCAAGCAAACCAACTACTCCTACGCCTATAAAAGAAGCTGTC
AGTAGTAAGCCTACGCCTAAGCCAAAAGCAAAAAAGAAGCGCCGTTTAAGAACGCGCTATAAAGTTTTGTTATCAGCGGT
GGTTTTAGTCATCGTAGCTCTGGTGGCTTTAGTCTATTTGAGTCCGTCAAATGTAAAAATCCCAGATGTTACTGGAAAAA
CTATTGCCCAAGCTCGTTCCGCTATTGAAACTGCAGGTTTGAAAGTTGGCAAGGAAAAAGACGAATACAGTGATTCTGTT
AAAAAAGATTCAGTTATTCGCACCAATCCAGAAGCGGGAACGCAACGTCGTGAGGGCAGTACGGTGGATCTGATTGTCTC
AAAAGGAACTAAAACTTTTATTATGGAAGATTATAAAGGTCAGAAAAGAGCAGATGCTATCAACAATCTGGTACAAAAAT
ACAAGGTTTCAAAAGGCTTAATTAAAACAGAAGAAGTGGAAAGTAATGAGTATGCGGCAGGAACAGTTGTTGATCAAACA
CCAGCAGCAGGCAGCACTTATGATTTGACTTCAAAGACACGTATTACGTTAAAAGTAGCGAAGTCCGTTTCAAGTGTCAC
GATGCCAAGCTATATCGGCTCAACCTATGAATTTGCTTATAATAATTTGACGGAAGTGATTGGTATTCAAGGTGCGAATA
TTGAAAAACGTACGGTTACAACAGCTCCAGCGGGTACACAGGCAAATACGATTATCAGACAAACCCCAGAAGCTGGTCAG
TCTTTGAATTTGAAGAGTGATCGCATTGTCTTATATGTATATGAGCCAAAAAACGAAGATTCTTCAACATCTGAAAGTAG
TTCACAATCTGATAGCAGCTCAAATAAAACTAGCCCATCCTCTAGCAGTTCGTCAACTAGTGGTAATGATGGAAGCAGCT
CAAAAACACCAGACACAAGTGCTAGTGCAAGTAATTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-232)

PASTA domain (PASTA)

(365-428)

PASTA domain (PASTA)

(506-574)

PASTA domain (PASTA)

(434-501)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

66.267

93.44

0.619
  stkP Streptococcus pneumoniae D39

65.925

93.44

0.616
  stkP Streptococcus pneumoniae R6

65.925

93.44

0.616
  stkP Streptococcus pneumoniae Rx1

65.753

93.44

0.614
  pknB Streptococcus mutans UA159

59.145

93.6

0.554
  stkP/pknB Streptococcus salivarius strain HSISS4

55.705

95.36

0.531

Multiple sequence alignment