Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   EHW89_RS01750 Genome accession   NZ_CP034543
Coordinates   341148..341900 (+) Length   250 a.a.
NCBI ID   WP_003031098.1    Uniprot ID   A0A3S4NJA6
Organism   Streptococcus periodonticum strain KCOM 2412     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 336148..346900
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EHW89_RS01735 (EHW89_01735) - 336532..338097 (-) 1566 WP_003025897.1 ABC transporter substrate-binding protein/permease -
  EHW89_RS01740 (EHW89_01740) - 338224..340113 (+) 1890 WP_126466498.1 DUF2207 domain-containing protein -
  EHW89_RS01745 (EHW89_01745) - 340180..341022 (+) 843 WP_126466499.1 undecaprenyl-diphosphate phosphatase -
  EHW89_RS01750 (EHW89_01750) mecA 341148..341900 (+) 753 WP_003031098.1 adaptor protein MecA Regulator
  EHW89_RS01755 (EHW89_01755) - 341891..343057 (+) 1167 WP_003036405.1 glycosyltransferase family 4 protein -
  EHW89_RS01760 (EHW89_01760) sufC 343148..343918 (+) 771 WP_003025885.1 Fe-S cluster assembly ATPase SufC -
  EHW89_RS01765 (EHW89_01765) sufD 343958..345220 (+) 1263 WP_126466500.1 Fe-S cluster assembly protein SufD -
  EHW89_RS01770 (EHW89_01770) - 345236..346468 (+) 1233 WP_126466501.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 250 a.a.        Molecular weight: 28968.85 Da        Isoelectric Point: 4.1610

>NTDB_id=331763 EHW89_RS01750 WP_003031098.1 341148..341900(+) (mecA) [Streptococcus periodonticum strain KCOM 2412]
MEMKQISDTTIKITIKLEDLEERGMEMADFLVPQEKTEEFFYAILDELEMPESFLDSGMLSFRVTPKPDRLDVFVTKSKI
DKNLNFDDLADLPDVEELSQMSPDEFLKTLEKNIFEKSKDDMEAVRSLETAEADDNTSTSDMESEENSDELTQKYIYYIL
KFSSLKEAIVFSKTVDYAVNTSELYKMDDHYYLTILVDIEGRPKRYPAWLLALMREHAEDTDVTRAVLQEHGYLLLVNEA
VASLKKVKCL

Nucleotide


Download         Length: 753 bp        

>NTDB_id=331763 EHW89_RS01750 WP_003031098.1 341148..341900(+) (mecA) [Streptococcus periodonticum strain KCOM 2412]
ATGGAAATGAAGCAAATTAGTGATACAACGATTAAAATCACAATAAAATTAGAGGATTTAGAGGAACGTGGGATGGAAAT
GGCAGATTTTCTAGTCCCACAAGAAAAAACAGAAGAGTTTTTCTATGCGATTTTAGATGAGTTGGAAATGCCAGAGAGCT
TTTTAGATAGTGGCATGCTCAGTTTTCGTGTGACACCAAAGCCCGACCGATTGGATGTCTTTGTCACCAAGTCTAAGATT
GATAAGAATTTGAACTTCGATGATTTGGCAGATTTACCAGATGTAGAAGAGCTGTCTCAAATGTCTCCAGATGAATTTTT
AAAGACATTAGAAAAAAATATTTTTGAGAAAAGTAAAGACGATATGGAGGCTGTTCGTTCTTTGGAAACGGCGGAAGCAG
ACGATAACACAAGCACTTCTGATATGGAGTCAGAGGAAAATAGTGACGAACTAACGCAGAAATATATTTATTACATTTTG
AAATTTTCCAGCCTGAAAGAAGCAATTGTTTTTTCTAAGACAGTAGATTATGCTGTCAATACTTCGGAGTTGTACAAAAT
GGACGACCACTATTATTTGACAATCTTGGTTGATATTGAAGGGCGTCCAAAGCGTTATCCAGCTTGGCTCCTGGCTTTGA
TGCGTGAACATGCAGAAGATACGGATGTGACAAGAGCTGTTTTGCAAGAGCACGGTTACTTATTGCTTGTCAACGAGGCG
GTTGCCAGTCTTAAAAAGGTTAAATGCTTATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-244)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3S4NJA6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

65.992

98.8

0.652
  mecA Streptococcus pneumoniae D39

65.992

98.8

0.652
  mecA Streptococcus pneumoniae R6

65.992

98.8

0.652
  mecA Streptococcus pneumoniae TIGR4

65.587

98.8

0.648
  mecA Streptococcus mutans UA159

50.201

99.6

0.5
  mecA Streptococcus thermophilus LMD-9

45.49

100

0.464
  mecA Streptococcus thermophilus LMG 18311

45.098

100

0.46

Multiple sequence alignment