Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   FGL73_RS06850 Genome accession   NZ_CP042408
Coordinates   1458348..1460228 (-) Length   626 a.a.
NCBI ID   WP_104141438.1    Uniprot ID   -
Organism   Lactococcus lactis strain CBA3619     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1453348..1465228
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL73_RS06820 (FGL73_06820) - 1453755..1454435 (-) 681 WP_012898438.1 5'-methylthioadenosine/adenosylhomocysteine nucleosidase -
  FGL73_RS06825 (FGL73_06825) macP 1454466..1454744 (-) 279 WP_003130796.1 cell wall synthase accessory phosphoprotein MacP -
  FGL73_RS06830 (FGL73_06830) - 1454737..1455321 (-) 585 WP_012898439.1 NUDIX hydrolase -
  FGL73_RS06835 (FGL73_06835) glmU 1455426..1456802 (-) 1377 WP_146978236.1 bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU -
  FGL73_RS06840 (FGL73_06840) proC 1457031..1457819 (+) 789 WP_038602002.1 pyrroline-5-carboxylate reductase -
  FGL73_RS06845 (FGL73_06845) rpsO 1457897..1458166 (-) 270 WP_010906184.1 30S ribosomal protein S15 -
  FGL73_RS06850 (FGL73_06850) stkP/pknB 1458348..1460228 (-) 1881 WP_104141438.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  FGL73_RS06855 (FGL73_06855) - 1460228..1461004 (-) 777 WP_038602007.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  FGL73_RS06860 (FGL73_06860) rsmB 1461085..1462359 (-) 1275 WP_038602010.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  FGL73_RS06865 (FGL73_06865) - 1462557..1463063 (-) 507 WP_012898444.1 Asp23/Gls24 family envelope stress response protein -
  FGL73_RS06870 (FGL73_06870) - 1463084..1463272 (-) 189 WP_012898445.1 DUF2273 domain-containing protein -
  FGL73_RS06875 (FGL73_06875) amaP 1463283..1463843 (-) 561 WP_038602014.1 alkaline shock response membrane anchor protein AmaP -
  FGL73_RS06880 (FGL73_06880) - 1463871..1464113 (-) 243 WP_038602017.1 GlsB/YeaQ/YmgE family stress response membrane protein -

Sequence

Protein


Download         Length: 626 a.a.        Molecular weight: 67846.09 Da        Isoelectric Point: 4.7476

>NTDB_id=331592 FGL73_RS06850 WP_104141438.1 1458348..1460228(-) (stkP/pknB) [Lactococcus lactis strain CBA3619]
MIQIGKIFADRYRIIKEIGRGGMANVYQGEDTFLGDRLVAIKVLRSNFENDDIAIARFQREAFAMAELSHPNIVGISDVG
EFESQQYIVMEFVDGMTLKQYINQNAPLANDEAIEIITEILSAMDMAHSHGIIHRDLKPQNVLVSSSGTVKVTDFGIAKA
LSETSLTQTNTMFGSVHYLSPEQARGSNATVQSDIYAIGIILFELLTGQIPFDGDSAVAIALKHFQESIPSIINLNPEVP
QALENVVIKATAKDIKNRYTDVEEMMTDVATSTSLDRRGEEKLVFNKDHDETKIMPANLINPYDTKPLIDKKEEEDSSTG
EKAISLEKGNKTKKPKKGLIIGLIILLLVVGGATLAWVVSTPTNVKVPNVTNSTLSQAEIKIKAANLKVGTVHKQQSSTI
DEGKVIKTDPDKGATVRSNSSVDIYLSTGNEDIIKMKDFVGEKIDEAMATLLKDYGIDESQVTQTSVPSDSYPAGTIIKQ
SPKKGSSFDTKGSQKITFEVSSGKQVEVPDYKPNGQYMTYSQYQAALKAAGFTNITLDPQATTNQQADGYVYSVYPNVGT
SVDPTQEIVVTYSVYNAPSSSSTTSESTTTPETSSSSSSSTTTTQSSPENANSSSTKESSTTTSSS

Nucleotide


Download         Length: 1881 bp        

>NTDB_id=331592 FGL73_RS06850 WP_104141438.1 1458348..1460228(-) (stkP/pknB) [Lactococcus lactis strain CBA3619]
ATGATTCAAATCGGTAAAATCTTTGCCGATCGTTATCGGATTATCAAAGAAATCGGACGCGGCGGAATGGCGAACGTTTA
TCAAGGTGAAGATACTTTTCTTGGTGACCGCTTAGTTGCAATAAAAGTGCTACGTTCAAATTTTGAAAATGATGACATTG
CGATTGCTCGTTTTCAGCGAGAAGCATTCGCCATGGCAGAACTTTCACATCCAAATATCGTAGGTATTTCTGACGTTGGT
GAATTTGAGAGTCAACAATACATTGTCATGGAATTTGTTGACGGCATGACACTCAAACAATACATCAATCAAAATGCACC
TTTAGCCAATGATGAAGCTATTGAAATTATTACTGAAATTTTATCAGCAATGGACATGGCCCATTCACATGGTATTATTC
ACCGGGATTTAAAACCACAAAATGTTTTAGTTTCCAGTAGTGGAACTGTAAAAGTAACGGATTTTGGAATTGCGAAAGCA
CTCTCTGAAACTTCACTTACTCAAACAAATACAATGTTTGGTTCGGTTCATTATTTATCACCAGAGCAAGCGCGTGGTTC
AAATGCGACTGTTCAATCAGATATTTATGCGATTGGAATTATTTTATTTGAACTTTTAACAGGTCAAATTCCATTTGATG
GAGATTCAGCCGTTGCTATTGCTCTAAAACATTTCCAAGAGAGTATTCCAAGCATCATTAATCTCAATCCAGAAGTTCCG
CAAGCTTTGGAAAATGTTGTCATTAAAGCTACAGCAAAAGATATTAAAAATCGCTATACTGATGTAGAAGAAATGATGAC
TGATGTGGCAACTTCAACGAGTCTTGACCGTCGTGGGGAAGAAAAATTAGTTTTCAATAAGGATCATGATGAGACTAAAA
TTATGCCTGCTAATTTAATCAATCCATATGATACTAAACCTCTGATTGATAAAAAAGAAGAAGAGGATTCATCAACAGGT
GAAAAAGCTATATCCTTAGAAAAAGGAAATAAAACCAAAAAACCTAAAAAAGGTCTGATTATTGGTCTGATTATTCTCCT
CTTAGTTGTTGGCGGTGCTACTTTGGCTTGGGTTGTATCAACACCAACCAATGTTAAGGTACCCAATGTAACAAATTCCA
CACTTAGTCAAGCTGAAATTAAAATTAAGGCTGCAAACCTTAAAGTGGGAACAGTTCATAAACAGCAAAGTTCAACGATT
GATGAAGGAAAGGTTATTAAAACTGATCCAGATAAAGGGGCAACCGTAAGATCCAACAGTTCAGTCGATATTTATCTTTC
CACAGGAAATGAAGATATCATCAAAATGAAGGACTTTGTCGGTGAAAAGATCGATGAGGCGATGGCAACATTACTTAAGG
ATTATGGTATTGATGAAAGCCAAGTCACTCAAACCTCCGTTCCTAGTGATTCTTACCCAGCAGGTACAATCATTAAACAA
AGTCCTAAAAAAGGTTCTAGTTTTGATACCAAAGGGAGTCAAAAAATTACCTTTGAAGTTTCAAGTGGAAAACAAGTTGA
AGTTCCAGATTATAAACCGAACGGTCAATATATGACTTATTCACAGTATCAAGCTGCCTTAAAAGCTGCAGGATTCACTA
ATATTACACTAGATCCTCAAGCGACAACAAATCAACAAGCTGATGGTTATGTTTACTCAGTGTATCCAAATGTAGGAACA
TCTGTTGATCCAACTCAAGAAATTGTAGTCACTTATAGCGTCTATAATGCTCCAAGTTCAAGTTCAACAACTTCTGAATC
AACAACGACGCCTGAAACATCGTCAAGCAGCTCGAGCTCCACAACAACAACTCAGTCATCACCAGAGAATGCTAATAGTA
GTAGTACTAAAGAATCTTCAACAACTACATCAAGTAGTTGA

Domains

Predicted by InterProScan.

Protein kinase domain (Pkinase)

(12-265)

PASTA domain (PASTA)

(434-501)

PASTA domain (PASTA)

(506-573)

PASTA domain (PASTA)

(365-428)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

45.84

100

0.466
  pknB Streptococcus mutans UA159

49.259

86.262

0.425
  stkP Streptococcus pneumoniae TIGR4

47.826

80.831

0.387
  stkP Streptococcus pneumoniae D39

47.628

80.831

0.385
  stkP Streptococcus pneumoniae R6

47.628

80.831

0.385
  stkP Streptococcus pneumoniae Rx1

47.431

80.831

0.383