Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   EJF26_RS09385 Genome accession   NZ_CP034442
Coordinates   1848673..1850556 (+) Length   627 a.a.
NCBI ID   WP_000614515.1    Uniprot ID   -
Organism   Streptococcus oralis subsp. dentisani strain F0392     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1843673..1855556
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EJF26_RS09370 fmt 1845679..1846614 (+) 936 WP_000163665.1 methionyl-tRNA formyltransferase -
  EJF26_RS09375 rsmB 1846607..1847920 (+) 1314 WP_004246110.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  EJF26_RS09380 - 1847936..1848676 (+) 741 WP_000401538.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  EJF26_RS09385 stkP 1848673..1850556 (+) 1884 WP_000614515.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  EJF26_RS09390 - 1850644..1851402 (+) 759 WP_000344524.1 threonine/serine exporter family protein -
  EJF26_RS09395 - 1851404..1851841 (+) 438 WP_000176904.1 threonine/serine exporter family protein -
  EJF26_RS09400 - 1851978..1853150 (+) 1173 WP_025168949.1 hydroxymethylglutaryl-CoA synthase -
  EJF26_RS09405 - 1853150..1854424 (+) 1275 WP_000750332.1 hydroxymethylglutaryl-CoA reductase, degradative -
  EJF26_RS09410 - 1854461..1855426 (-) 966 WP_000225991.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 627 a.a.        Molecular weight: 68390.68 Da        Isoelectric Point: 9.2160

>NTDB_id=331401 EJF26_RS09385 WP_000614515.1 1848673..1850556(+) (stkP) [Streptococcus oralis subsp. dentisani strain F0392]
MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHSPLSNEEAVRIMGQILLAMRLAHTRGIIHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPAVP
QALENVVIKATAKKLTDRYQSVSEMYVDLSSCLSHNRRREPKLVFDEASKVDTKTLPKVPQSTLTSIPKAKPQLERPQSK
QQTQQVVDEAPVPKPTKKRKFKARYMILLASALLVAASLIWIFSRTPATIAIPDVSGQTVAEAKETLKKANFEVGEEKTE
ASDTVAEGRVIRTDPEARSGRKEGSKVNLIVSSGKQSFQLSNYVGRKSSDVVAELKEKKVPENLIKIEEEESSESDPGTV
IRQTPAAGSTYDLTKASTITLTVAKKVTSVSMPSYIGSSLEFTKNNLTQIVGVKEANIEVVEVSTAPEGTTAGTVVSQDP
KPGEKVDLNKTRVKISIYKPKPLPSSSSSSQHGNSGTDTTPSQSNNQGSNPTTDSSDGSRTSSNERN

Nucleotide


Download         Length: 1884 bp        

>NTDB_id=331401 EJF26_RS09385 WP_000614515.1 1848673..1850556(+) (stkP) [Streptococcus oralis subsp. dentisani strain F0392]
ATGATCCAGATCGGCAAGATTTTTGCCGGACGATATCGGATTGTCAAACAGATTGGTCGAGGAGGCATGGCGGATGTTTA
CTTGGCCAAGGATTTGATCCTAGACGGGGAAGAAGTGGCGGTTAAGGTCCTGAGGACTAACTATCAGACAGATCCGATTG
CTGTGGCACGTTTTCAACGTGAAGCGAGAGCCATGGCGGATCTGGATCATCCCCATATCGTTCGAATAACAGATATCGGT
GAGGAAGACGGTCAGCAGTACCTAGCTATGGAGTATGTGGCAGGGCTTGACCTCAAACGTTATATCAAAGAACACTCCCC
TCTCTCAAATGAAGAAGCCGTCCGTATTATGGGACAGATTCTCTTGGCGATGCGTCTGGCGCATACGAGAGGGATTATCC
ACCGAGATTTGAAACCTCAAAATATCCTATTGACACCAGATGGAACTGCCAAAGTTACAGACTTTGGGATTGCCGTGGCC
TTTGCAGAGACCAGTCTGACACAGACCAACTCCATGCTCGGTTCAGTTCACTATCTCTCACCTGAGCAGGCCCGTGGTTC
CAAGGCAACTGTGCAGAGTGACATCTATGCTATGGGGATTATTTTCTATGAAATGTTGACTGGACATATCCCTTATGATG
GGGATAGTGCAGTGACTATTGCCCTCCAGCATTTCCAAAAACCACTCCCATCTGTTATTGCTGAGAATCCAGCAGTACCA
CAAGCTTTGGAAAATGTCGTTATCAAGGCAACGGCCAAGAAATTAACAGATCGCTATCAGTCTGTATCAGAAATGTATGT
GGACTTGTCGAGTTGTTTATCTCACAATCGTAGGAGAGAACCAAAGCTAGTCTTTGATGAGGCAAGCAAGGTTGATACCA
AGACCTTGCCTAAAGTTCCACAAAGCACTCTGACCTCTATTCCGAAGGCTAAGCCACAATTAGAGCGACCTCAATCAAAA
CAGCAGACTCAGCAGGTGGTAGATGAAGCACCAGTACCAAAACCAACGAAAAAACGGAAGTTTAAAGCTCGCTACATGAT
TTTACTGGCCAGTGCCTTGCTAGTTGCAGCCTCTTTGATTTGGATCTTCTCCCGAACTCCAGCGACTATTGCTATTCCAG
ATGTATCGGGACAGACAGTTGCTGAAGCTAAAGAAACACTGAAGAAAGCTAATTTTGAAGTAGGTGAAGAAAAGACCGAG
GCCAGCGACACAGTAGCCGAAGGTCGCGTCATTCGAACAGATCCAGAAGCTAGAAGCGGTCGAAAAGAAGGAAGCAAAGT
AAATCTAATCGTTTCATCAGGTAAGCAATCCTTCCAACTAAGTAACTATGTAGGACGTAAGTCCTCGGATGTTGTCGCAG
AGCTCAAAGAGAAAAAGGTTCCAGAAAATCTTATCAAGATCGAGGAAGAGGAATCTAGCGAAAGCGATCCAGGAACAGTC
ATTAGGCAAACCCCAGCTGCAGGAAGTACTTACGACCTCACGAAAGCCAGCACGATTACCTTAACAGTTGCTAAGAAGGT
AACTAGTGTCTCGATGCCAAGTTACATTGGTTCAAGTCTCGAATTTACTAAGAACAATTTGACTCAGATTGTTGGTGTAA
AAGAGGCCAATATCGAAGTTGTGGAAGTATCAACTGCTCCTGAAGGAACTACTGCAGGAACAGTTGTTAGTCAGGATCCT
AAACCTGGAGAAAAGGTAGATCTCAATAAAACACGTGTTAAGATTTCTATTTATAAACCAAAACCACTTCCTTCTTCATC
AAGTTCGTCTCAACACGGAAATTCAGGAACAGACACGACGCCTTCACAGAGTAACAATCAAGGTAGCAATCCTACAACGG
ATTCTTCAGATGGCAGTAGAACGTCAAGTAATGAACGAAATTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-227)

PASTA domain (PASTA)

(441-505)

PASTA domain (PASTA)

(371-432)

PASTA domain (PASTA)

(510-579)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

77.358

92.982

0.719
  stkP Streptococcus pneumoniae D39

77.015

92.982

0.716
  stkP Streptococcus pneumoniae R6

77.015

92.982

0.716
  stkP Streptococcus pneumoniae Rx1

76.844

92.982

0.715
  pknB Streptococcus mutans UA159

56.282

92.663

0.522
  stkP/pknB Streptococcus salivarius strain HSISS4

50.918

95.534

0.486

Multiple sequence alignment