Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   EJF26_RS01345 Genome accession   NZ_CP034442
Coordinates   253158..253898 (+) Length   246 a.a.
NCBI ID   WP_000782708.1    Uniprot ID   F9P075
Organism   Streptococcus oralis subsp. dentisani strain F0392     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 248158..258898
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EJF26_RS01335 - 248982..251507 (+) 2526 WP_000182501.1 MBL fold metallo-hydrolase -
  EJF26_RS01340 - 251557..253035 (-) 1479 WP_000789700.1 oligosaccharide flippase family protein -
  EJF26_RS01345 mecA 253158..253898 (+) 741 WP_000782708.1 adaptor protein MecA Regulator
  EJF26_RS01350 - 254019..255305 (+) 1287 WP_000216358.1 homoserine dehydrogenase -
  EJF26_RS01355 thrB 255307..256176 (+) 870 WP_000692413.1 homoserine kinase -
  EJF26_RS01360 msrB 256275..257213 (+) 939 WP_000818212.1 peptide-methionine (R)-S-oxide reductase MsrB -

Sequence

Protein


Download         Length: 246 a.a.        Molecular weight: 28509.31 Da        Isoelectric Point: 4.1311

>NTDB_id=331332 EJF26_RS01345 WP_000782708.1 253158..253898(+) (mecA) [Streptococcus oralis subsp. dentisani strain F0392]
MKMKQISDTTLKITMTLDDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPDNFLDSGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFEDLADLPDMEELAQMSPDEFLKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQANKETESKKEPYIYYILRFA
SLADLVAFAKTVNYQMETSELYKMNGHYYLTILVDVENHPSPYPAWLLARMREFADDSDISRSVLQEYGRILINHDAVLG
LQKINN

Nucleotide


Download         Length: 741 bp        

>NTDB_id=331332 EJF26_RS01345 WP_000782708.1 253158..253898(+) (mecA) [Streptococcus oralis subsp. dentisani strain F0392]
ATGAAGATGAAACAAATTAGTGATACGACACTGAAAATCACGATGACTTTAGATGATTTGATGGATCGGGGAATGGAGAT
TGCAGATTTTCTCGTTCCTCAGGAAAAAACAGAAGAGTTTTTCTATGCTATTTTAGATGAATTAGAAATGCCAGACAATT
TCTTGGATAGTGGCATGCTGAGTTTCCGTGTGACGCCAAAACCAGATAAGGTGGATGTCTTTGTGACCAAGTCTAAGATT
GATCAAAATCTGGATTTTGAAGATTTGGCTGACCTACCTGACATGGAAGAATTAGCCCAAATGTCGCCGGATGAATTTCT
CAAAACCTTGGAGAAGAGCATTGCAGACAAGACTAAGGATGATATTGAGGCCATCCAATCCCTAGAACAGGTCGAGGCTA
AGGAAGAGGAGCAAGAGCAAGCGAACAAGGAGACTGAGAGTAAGAAGGAACCTTATATCTACTATATCTTGCGTTTTGCA
AGTCTTGCTGACTTAGTTGCTTTTGCAAAGACTGTTAACTACCAGATGGAAACATCTGAACTCTACAAGATGAATGGACA
CTACTATTTGACAATCTTGGTCGATGTGGAAAATCATCCTAGTCCATACCCAGCCTGGCTCTTGGCCCGTATGCGTGAAT
TTGCAGATGATAGTGACATCAGTCGCTCAGTCTTGCAAGAGTATGGTCGCATCTTGATCAATCATGACGCGGTGCTCGGT
CTTCAAAAAATTAACAATTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F9P075

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

90.204

99.593

0.898
  mecA Streptococcus pneumoniae D39

90.204

99.593

0.898
  mecA Streptococcus pneumoniae R6

90.204

99.593

0.898
  mecA Streptococcus pneumoniae TIGR4

89.796

99.593

0.894
  mecA Streptococcus thermophilus LMD-9

47.791

100

0.484
  mecA Streptococcus thermophilus LMG 18311

47.39

100

0.48
  mecA Streptococcus mutans UA159

48.163

99.593

0.48

Multiple sequence alignment