Detailed information NTG0330650

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: DNK17_RS03045
• Genome accession: NZ_CP034315
• Coordinates: 578064..579293 (+)
• Length: 409 a.a.
• NCBI ID: WP_000728356.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain TFJ0901
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 573064..584293

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DNK17_RS03020 (DNK17_03020)	-	574224..576803 (+)	2580	WP_000154432.1	YfhO family protein	-
DNK17_RS03040 (DNK17_03040)	rlmH	577384..577863 (-)	480	WP_000768335.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
DNK17_RS03045 (DNK17_03045)	htrA	578064..579293 (+)	1230	WP_000728356.1	trypsin-like peptidase domain-containing protein	Regulator
DNK17_RS03050 (DNK17_03050)	spo0J	579391..580164 (+)	774	WP_000456088.1	ParB/RepB/Spo0J family partition protein	Regulator
DNK17_RS03055 (DNK17_03055)	dnaA	580373..581734 (+)	1362	WP_000138202.1	chromosomal replication initiator protein DnaA	-
DNK17_RS03060 (DNK17_03060)	dnaN	581889..583025 (+)	1137	WP_000581132.1	DNA polymerase III subunit beta	-
DNK17_RS03065 (DNK17_03065)	-	583083..583976 (+)	894	WP_000987448.1	diacylglycerol kinase family protein	-
DNK17_RS03070 (DNK17_03070)	-	583986..584183 (+)	198	WP_000285199.1	DUF951 family protein	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 43104.56 Da
• Isoelectric Point: 9.5271

>NTDB_id=330650 DNK17_RS03045 WP_000728356.1 578064..579293(+) (htrA) [Streptococcus agalactiae strain TFJ0901]
MKKKLVSSLLKCSLIIIVSFAGGAFASFVMNHNDNIPNGGVTKTSKVNYNNITPTTKAVKKVQNSVVSVINYKQQESRSD
LSDFYSHFFGNQGGNTDKGLQVYGEGSGVIYKKDGKNAYVVTNNHVIDGAKQIEIQLADGSKAVGKLVGSDTYSDLAVVK
IPSDKVSNIAEFADSSKLNIGETAIAIGSPLGTEYANSVTQGIVSSLKRTVTMTNEEGQTVSTNAIQTDAAINPGNSGGA
LINIEGQVIGINSSKISSTSNQTSGQSSGNSVEGMGFAIPSNDVVKIINQLESNGQVERPALGISMAGLSNLPSDVISKL
KIPSNVTNGIVVASIQSGMPAQGKLKKYDVITKVDDKEVASPSDLQSLLYGHQVGDSITVTFYRGENKQTITIKLTKTSK
DLAKQRANN

Nucleotide

• Length: 1230 bp

>NTDB_id=330650 DNK17_RS03045 WP_000728356.1 578064..579293(+) (htrA) [Streptococcus agalactiae strain TFJ0901]
GTGAAAAAAAAATTAGTCTCATCACTTCTAAAGTGTTCTCTAATCATTATTGTTAGCTTTGCTGGTGGAGCATTTGCTAG
TTTTGTCATGAATCATAATGACAATATTCCAAATGGTGGTGTCACTAAAACTAGTAAAGTAAATTATAATAACATAACGC
CTACAACAAAAGCTGTTAAAAAGGTACAAAATAGTGTTGTTTCTGTTATCAATTATAAACAACAAGAGAGTCGTTCTGAC
CTATCAGACTTCTATAGTCATTTTTTTGGTAATCAGGGGGGCAACACTGATAAGGGCTTACAAGTTTACGGTGAAGGCTC
TGGAGTCATCTATAAAAAAGATGGTAAAAATGCCTATGTTGTCACTAATAACCACGTCATTGATGGGGCTAAACAAATTG
AAATTCAACTAGCTGATGGCTCAAAAGCAGTTGGGAAACTTGTTGGGTCAGATACCTACTCTGATTTAGCCGTCGTCAAA
ATTCCATCAGATAAGGTTTCAAATATTGCAGAATTTGCTGATTCATCAAAACTCAACATTGGTGAAACTGCTATAGCGAT
CGGAAGCCCTCTTGGAACTGAGTATGCAAATTCTGTAACTCAAGGTATTGTATCTAGTTTAAAAAGAACTGTAACAATGA
CTAATGAAGAAGGACAAACAGTTTCTACAAATGCTATCCAGACTGATGCTGCTATCAATCCTGGTAATTCAGGTGGAGCA
CTTATCAATATTGAAGGACAGGTTATTGGAATTAATTCTAGTAAAATTTCTTCTACATCAAATCAAACCTCAGGACAATC
GTCAGGAAATAGCGTTGAAGGTATGGGATTTGCCATTCCTTCAAATGATGTTGTTAAGATTATCAATCAACTTGAGAGTA
ACGGACAAGTAGAGAGACCTGCTCTAGGTATTTCTATGGCTGGATTAAGTAATTTACCATCCGATGTTATTAGTAAACTG
AAAATCCCAAGTAATGTTACTAATGGTATTGTAGTAGCATCTATCCAATCTGGCATGCCAGCTCAAGGCAAACTAAAGAA
ATACGATGTCATTACTAAAGTTGACGATAAAGAAGTAGCATCTCCAAGTGATTTACAAAGTTTACTCTATGGCCACCAGG
TAGGAGATTCCATAACAGTAACCTTTTACCGTGGTGAAAATAAACAAACAATCACTATAAAACTTACTAAAACTAGTAAA
GATTTAGCTAAACAACGAGCAAATAACTAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (106-251)

• PDZ domain (PDZ_2) (300-395)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	63.104	96.088	0.606
htrA	Streptococcus gordonii str. Challis substr. CH1	57.357	98.044	0.562
htrA	Streptococcus mitis NCTC 12261	56.533	97.311	0.55
htrA	Streptococcus pneumoniae TIGR4	55.037	99.511	0.548
htrA	Streptococcus pneumoniae Rx1	55.037	99.511	0.548
htrA	Streptococcus pneumoniae D39	55.037	99.511	0.548
htrA	Streptococcus pneumoniae R6	55.037	99.511	0.548