Detailed information NTG0032928

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: SUB_RS04665
• Genome accession: NC_012004
• Coordinates: 905599..906444 (-)
• Length: 281 a.a.
• NCBI ID: WP_012658425.1
• Uniprot ID: A0A6L6GA51
• Organism: Streptococcus uberis 0140J
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 900599..911444

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SUB_RS04645 (SUB0922)	-	900879..901592 (-)	714	WP_012658421.1	DUF3307 domain-containing protein	-
SUB_RS04650 (SUB0923)	-	901585..902259 (-)	675	WP_012658422.1	SatD family protein	-
SUB_RS04655 (SUB0924)	-	902444..903328 (+)	885	WP_012658423.1	LysR family transcriptional regulator	-
SUB_RS04660 (SUB0925)	topA	903362..905494 (-)	2133	WP_012658424.1	type I DNA topoisomerase	-
SUB_RS04665 (SUB0926)	dprA	905599..906444 (-)	846	WP_012658425.1	DNA-processing protein DprA	Machinery gene
SUB_RS04670 (SUB0927)	-	906502..907047 (-)	546	WP_012658426.1	sugar O-acetyltransferase	-
SUB_RS04675 (SUB0928)	-	907078..907851 (-)	774	WP_012658427.1	ribonuclease HII	-
SUB_RS04680 (SUB0929)	ylqF	907835..908689 (-)	855	WP_012658428.1	ribosome biogenesis GTPase YlqF	-
SUB_RS04685 (SUB0930)	-	908856..909299 (+)	444	WP_100912040.1	DUF1836 domain-containing protein	-
SUB_RS04690 (SUB0931)	trhA	909302..909952 (+)	651	WP_012658430.1	PAQR family membrane homeostasis protein TrhA	-
SUB_RS04695 (SUB0932)	-	910036..910938 (+)	903	WP_012658431.1	diacylglycerol/lipid kinase family protein	-
SUB_RS09310 (SUB0933)	-	910985..911332 (-)	348	WP_012658432.1	hypothetical protein	-

Sequence

Protein

• Length: 281 a.a.
• Molecular weight: 31337.29 Da
• Isoelectric Point: 9.3793

>NTDB_id=32928 SUB_RS04665 WP_012658425.1 905599..906444(-) (dprA) [Streptococcus uberis 0140J]
MNNFDIFKLKCAGLKNHHILNIIAYMKHSTQSLSLSLRNMAVVSKCSDPITFIENYKALKSKELRKIFMEYPSISILDKE
YPALLKEIHNPPVLFFYQGNIKLLDSPKLAIVGSRKASETGIKSVQKIVEELNNKYVIVSGLARGIDTAAHLSSLRNGGQ
TIAIIGSGFNNIYPKENRRLQDYIGQHHLLISEYAPNDKPYSFHFPERNRIIAGLVKAVLVVEAKKRSGSLITCQHALDE
GRDVYAIPGNIIDGFSDGCNLLIQEGAKCVTNGFQISSELF

Nucleotide

• Length: 846 bp

>NTDB_id=32928 SUB_RS04665 WP_012658425.1 905599..906444(-) (dprA) [Streptococcus uberis 0140J]
ATGAATAATTTTGACATTTTTAAACTTAAGTGTGCCGGACTAAAAAATCATCACATTCTGAATATCATCGCCTACATGAA
ACACTCTACACAATCACTTTCTTTATCTTTACGAAATATGGCTGTTGTATCCAAATGTAGTGATCCCATTACATTCATAG
AGAACTATAAAGCATTAAAAAGTAAGGAACTTAGAAAAATTTTCATGGAATATCCTTCCATTTCTATTCTAGATAAGGAA
TACCCAGCTCTATTAAAAGAAATTCATAATCCACCAGTTTTATTCTTCTACCAAGGAAATATCAAACTACTAGATTCACC
TAAACTAGCTATTGTTGGGTCTAGAAAGGCTTCCGAAACAGGAATAAAAAGTGTCCAAAAAATTGTTGAAGAATTAAATA
ATAAATATGTTATTGTCAGTGGACTTGCTAGAGGCATCGACACAGCCGCTCACCTCAGTAGTTTAAGAAATGGTGGTCAA
ACAATTGCAATTATTGGTTCTGGTTTTAATAACATATATCCTAAAGAAAATCGCCGCTTACAAGATTATATTGGTCAACA
TCATCTCCTTATATCAGAATATGCCCCTAATGATAAGCCATATTCCTTTCACTTTCCTGAACGAAATCGTATTATTGCAG
GTCTCGTAAAAGCAGTATTAGTAGTTGAAGCAAAAAAACGCTCTGGAAGTTTGATAACCTGTCAACATGCATTGGATGAA
GGACGTGACGTTTATGCTATTCCAGGAAATATTATCGATGGATTTTCTGATGGTTGTAATTTATTGATTCAAGAAGGCGC
AAAGTGCGTGACCAATGGCTTTCAAATCAGTTCTGAACTTTTTTGA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (74-271)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-64)

3D structure

• AlphaFold DB: A0A6L6GA51

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	62.857	99.644	0.626
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	55	99.644	0.548
dprA/cilB/dalA	Streptococcus pneumoniae D39	55	99.644	0.548
dprA/cilB/dalA	Streptococcus pneumoniae R6	55	99.644	0.548
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	55	99.644	0.548
dprA/cilB/dalA	Streptococcus mitis SK321	55	99.644	0.548
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	54.643	99.644	0.544
dprA	Lactococcus lactis subsp. cremoris KW2	54.48	99.288	0.541
dprA	Vibrio campbellii strain DS40M4	36.177	100	0.377