Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   SUB_RS01795 Genome accession   NC_012004
Coordinates   336792..337550 (+) Length   252 a.a.
NCBI ID   WP_012657878.1    Uniprot ID   B9DTL0
Organism   Streptococcus uberis 0140J     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 331792..342550
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SUB_RS01780 (SUB0337) - 332115..333665 (-) 1551 WP_012657875.1 ABC transporter substrate-binding protein/permease -
  SUB_RS01785 (SUB0338) - 333867..335768 (+) 1902 WP_012657876.1 DUF2207 domain-containing protein -
  SUB_RS01790 (SUB0339) - 335838..336677 (+) 840 WP_012657877.1 undecaprenyl-diphosphate phosphatase -
  SUB_RS01795 (SUB0340) mecA 336792..337550 (+) 759 WP_012657878.1 adaptor protein MecA Regulator
  SUB_RS01800 (SUB0341) - 337557..338714 (+) 1158 WP_012657879.1 glycosyltransferase family 4 protein -
  SUB_RS01805 (SUB0342) - 338997..339353 (+) 357 WP_012657880.1 hypothetical protein -
  SUB_RS01810 (SUB0343) sufC 339551..340321 (+) 771 WP_012657881.1 Fe-S cluster assembly ATPase SufC -
  SUB_RS01815 (SUB0344) sufD 340427..341698 (+) 1272 WP_012657882.1 Fe-S cluster assembly protein SufD -

Sequence

Protein


Download         Length: 252 a.a.        Molecular weight: 29392.19 Da        Isoelectric Point: 4.1676

>NTDB_id=32911 SUB_RS01795 WP_012657878.1 336792..337550(+) (mecA) [Streptococcus uberis 0140J]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSDL
NKEINFDDLADLGDVSQMTPEDFFKTIEKSMIEKGDVNAHEKLEKIEEMMEEAVDAVMTQNAEEQKEEESPFEPLDYVHY
VLDFMTIQDAITFSKTVTFPIEASELYKSSDRYHMTILLDIQNQPSYYANVMYARLIEHALPGSKTRAYLQEHAHQLLED
HAVTELQKVELV

Nucleotide


Download         Length: 759 bp        

>NTDB_id=32911 SUB_RS01795 WP_012657878.1 336792..337550(+) (mecA) [Streptococcus uberis 0140J]
ATGGAAATGAAACAAATCAGCGAAACAACGCTAAAAATCACTATTAGTATGGATGATCTGGAAGAAAGAGGAATGGAGTT
AAAAGACTTCTTAATCCCTCAAGAAAAAACGGAAGAATTCTTTTACACTGTCATGGATGAGCTAGACTTACCTGATAATT
TTAAAGACAGTGGTATGTTAAGTTTCCGAGTTACTCCAAGAAAGGACCGTTTGGATGTCTTTGTCACCAAATCAGATTTG
AATAAAGAAATTAATTTTGATGATTTGGCAGACTTGGGAGATGTTTCTCAAATGACACCTGAAGACTTCTTCAAAACAAT
TGAGAAGAGTATGATTGAAAAAGGTGATGTTAACGCTCATGAGAAACTAGAGAAAATTGAAGAAATGATGGAAGAAGCAG
TGGATGCTGTTATGACGCAAAATGCTGAAGAGCAAAAGGAAGAAGAGTCACCTTTTGAACCTCTAGATTATGTGCATTAC
GTTTTGGATTTCATGACCATTCAAGATGCCATTACCTTTTCTAAAACAGTGACCTTCCCGATAGAAGCTTCTGAATTATA
TAAAAGTTCTGACCGATATCACATGACCATTTTATTGGACATTCAAAACCAACCTTCTTATTATGCCAATGTCATGTATG
CTAGATTAATTGAGCATGCACTCCCAGGTAGTAAGACTAGAGCTTACTTGCAGGAACATGCCCATCAATTACTGGAAGAT
CATGCAGTAACAGAACTACAAAAAGTAGAGTTGGTGTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-246)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B9DTL0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

63.855

98.81

0.631
  mecA Streptococcus thermophilus LMD-9

59.274

98.413

0.583
  mecA Streptococcus thermophilus LMG 18311

58.871

98.413

0.579
  mecA Streptococcus pneumoniae Rx1

49.213

100

0.496
  mecA Streptococcus pneumoniae D39

49.213

100

0.496
  mecA Streptococcus pneumoniae R6

49.213

100

0.496
  mecA Streptococcus pneumoniae TIGR4

49.213

100

0.496

Multiple sequence alignment