Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   SP670_RS11085 Genome accession   NC_014498
Coordinates   2030584..2031600 (-) Length   338 a.a.
NCBI ID   WP_000355367.1    Uniprot ID   -
Organism   Streptococcus pneumoniae 670-6B     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2025584..2036600
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SP670_RS11050 - 2025619..2025939 (-) 321 WP_223687705.1 HTH domain-containing protein -
  SP670_RS11055 (SP670_2183) - 2026054..2026260 (-) 207 WP_000041498.1 helix-turn-helix transcriptional regulator -
  SP670_RS11060 (SP670_2184) - 2026411..2026572 (+) 162 WP_226323615.1 hypothetical protein -
  SP670_RS13970 (SP670_2185) - 2026565..2026735 (-) 171 WP_000656630.1 hypothetical protein -
  SP670_RS13975 - 2026732..2026875 (-) 144 WP_000389590.1 hypothetical protein -
  SP670_RS14525 (SP670_2186) - 2027270..2027392 (-) 123 WP_001003831.1 hypothetical protein -
  SP670_RS11065 (SP670_2187) - 2027469..2027744 (-) 276 WP_001094376.1 hypothetical protein -
  SP670_RS11070 (SP670_2188) - 2027906..2028673 (+) 768 WP_000862003.1 S24 family peptidase -
  SP670_RS11075 - 2028675..2028875 (+) 201 WP_000064302.1 hypothetical protein -
  SP670_RS11080 (SP670_2190) - 2029057..2030502 (+) 1446 WP_000633509.1 recombinase family protein -
  SP670_RS11085 (SP670_2191) comGB/cglB 2030584..2031600 (-) 1017 WP_000355367.1 competence type IV pilus assembly protein ComGB Machinery gene
  SP670_RS11090 (SP670_2192) comGA/cglA/cilD 2031548..2032489 (-) 942 WP_000249563.1 competence type IV pilus ATPase ComGA Machinery gene
  SP670_RS11095 (SP670_2193) - 2032565..2032930 (-) 366 WP_000286415.1 DUF1033 family protein -
  SP670_RS11100 (SP670_2194) - 2033081..2034139 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  SP670_RS11105 (SP670_2195) nagA 2034302..2035453 (-) 1152 WP_001134546.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38381.34 Da        Isoelectric Point: 9.5924

>NTDB_id=32878 SP670_RS11085 WP_000355367.1 2030584..2031600(-) (comGB/cglB) [Streptococcus pneumoniae 670-6B]
MDISQAFKLKRKKLATAKQKNIITLFNNLFSSGFHLVETISFLDRSALLDKQCVTQMRTGLSQGKSFSEMMESLGFSSAI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
LGMVGFVSVGVLLALTFYKRSSKMRVFSILARLPFLGIFVQTYLTAYYAREWGNMISQGMELTQIFQIMQEQGSQLFKEI
GQDLAQALQNGREFSQTIATYPFFKKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=32878 SP670_RS11085 WP_000355367.1 2030584..2031600(-) (comGB/cglB) [Streptococcus pneumoniae 670-6B]
ATGGACATATCACAAGCCTTCAAGCTGAAACGGAAAAAATTAGCTACAGCTAAGCAAAAAAATATCATCACCTTGTTTAA
CAATCTCTTTTCCAGCGGTTTTCATCTGGTGGAGACTATCTCCTTTTTAGATAGGAGTGCCTTGTTGGATAAGCAGTGTG
TGACTCAGATGCGCACGGGCTTGTCTCAGGGGAAATCATTCTCAGAAATGATGGAAAGTTTGGGATTTTCAAGTGCCATT
GTCACTCAGTTATCCCTAGCGGAAGTCCATGGAAATCTCCACCTGAGTTTGGGAAAGATAGAAGAGTATCTAGACAATCT
TGCCAAGGTCAAGAAAAAGTTAATTGAAGTAGCGACCTATCCCTTGATTTTGCTGGGTTTTCTTCTCTTAATTATGCTGG
GACTACGTAACTATCTACTACCACAACTGGATAGTAGCAATATTGCTACCCAAATCATCGGCAATCTGCCACAAATCTTT
CTAGGAATGGTAGGATTTGTTTCAGTAGGTGTCCTTTTAGCACTCACTTTTTATAAAAGAAGTTCTAAGATGCGCGTCTT
TTCTATCTTAGCACGCCTTCCCTTTCTTGGAATCTTTGTGCAGACCTATTTGACAGCCTATTATGCGCGTGAATGGGGGA
ATATGATTTCGCAGGGGATGGAGTTGACGCAGATTTTTCAGATCATGCAGGAACAAGGTTCCCAACTCTTTAAAGAAATC
GGTCAAGATTTAGCTCAAGCCCTACAAAATGGTCGCGAATTTTCTCAAACCATAGCAACCTATCCTTTCTTTAAAAAGGA
ATTGAGTCTCATCATAGAGTATGGGGAAGTTAAGTCCAAGCTGGGTAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATCTTTGTGGCACTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterProScan.

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus mitis NCTC 12261

97.337

100

0.973
  comGB/cglB Streptococcus mitis SK321

97.041

100

0.97
  comGB/cglB Streptococcus pneumoniae Rx1

95.266

100

0.953
  comGB/cglB Streptococcus pneumoniae D39

95.266

100

0.953
  comGB/cglB Streptococcus pneumoniae R6

95.266

100

0.953
  comGB/cglB Streptococcus pneumoniae TIGR4

95.266

100

0.953
  comGB Streptococcus gordonii str. Challis substr. CH1

73.512

99.408

0.731
  comGB Streptococcus mutans UA140

58.934

94.379

0.556
  comGB Streptococcus mutans UA159

58.934

94.379

0.556
  comGB Lactococcus lactis subsp. cremoris KW2

50.299

98.817

0.497

Multiple sequence alignment