Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilE   Type   Machinery gene
Locus tag   EGH12_RS10580 Genome accession   NZ_CP034020
Coordinates   1794867..1795385 (+) Length   172 a.a.
NCBI ID   WP_124935101.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain FQ48     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1789867..1800385
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGH12_RS10540 (EGH12_10540) - 1790008..1790403 (+) 396 Protein_1819 pilin -
  EGH12_RS10550 (EGH12_10550) - 1790941..1791339 (+) 399 Protein_1820 pilin -
  EGH12_RS10555 (EGH12_10555) - 1791543..1791929 (+) 387 Protein_1821 pilin -
  EGH12_RS10560 (EGH12_10560) lpxC 1792432..1793355 (+) 924 WP_003687007.1 UDP-3-O-acyl-N-acetylglucosamine deacetylase -
  EGH12_RS10565 (EGH12_10565) - 1793484..1793882 (+) 399 Protein_1823 pilin -
  EGH12_RS10575 (EGH12_10575) - 1794347..1794490 (+) 144 WP_012503975.1 hypothetical protein -
  EGH12_RS10580 (EGH12_10580) pilE 1794867..1795385 (+) 519 WP_124935101.1 pilin Machinery gene
  EGH12_RS10585 (EGH12_10585) pilA 1795688..1796941 (-) 1254 WP_047921365.1 signal recognition particle-docking protein FtsY Machinery gene
  EGH12_RS10595 (EGH12_10595) msrAB 1797087..1798655 (+) 1569 WP_003694393.1 bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB -
  EGH12_RS10600 (EGH12_10600) - 1798739..1799224 (-) 486 WP_003687001.1 CinA family protein -
  EGH12_RS10605 (EGH12_10605) - 1799250..1800098 (-) 849 WP_003687000.1 mechanosensitive ion channel family protein -

Sequence

Protein


Download         Length: 172 a.a.        Molecular weight: 18333.74 Da        Isoelectric Point: 7.8392

>NTDB_id=328160 EGH12_RS10580 WP_124935101.1 1794867..1795385(+) (pilE) [Neisseria gonorrhoeae strain FQ48]
MNTLQKGFTLIELMIVIAIVGILAAVALPAYQDYTARAQVSEAILLAEGQKSAVTGYYLNHGEWPKDNTSAGVASASTIK
GKYVQSVTVANGVVTAQMKSDGVNKEIKGKKLSLWAKRQDGSVKWFCGQPVKRDNAKDADDVTDDAGTDNGGKGKIDTKH
LPSTCRDESTAE

Nucleotide


Download         Length: 519 bp        

>NTDB_id=328160 EGH12_RS10580 WP_124935101.1 1794867..1795385(+) (pilE) [Neisseria gonorrhoeae strain FQ48]
ATGAATACCCTTCAAAAAGGCTTTACCCTTATCGAGCTGATGATTGTGATCGCCATCGTCGGCATTTTGGCGGCAGTCGC
CCTTCCCGCCTACCAAGACTACACCGCCCGCGCGCAAGTTTCCGAAGCCATCCTTTTGGCCGAAGGTCAAAAATCAGCCG
TTACCGGGTATTACCTGAATCACGGCGAATGGCCCAAAGACAACACTTCTGCCGGCGTGGCATCCGCTTCAACAATCAAA
GGCAAATATGTTCAAAGCGTTACGGTCGCAAACGGCGTCGTTACCGCCCAAATGAAATCAGACGGCGTAAACAAAGAAAT
CAAAGGCAAAAAACTCTCCCTGTGGGCCAAGCGTCAAGACGGTTCGGTAAAATGGTTCTGCGGACAGCCGGTTAAGCGCG
ACAACGCCAAAGACGCCGACGACGTTACCGACGACGCCGGCACCGACAACGGCGGCAAAGGCAAAATCGACACCAAGCAC
CTGCCGTCAACCTGCCGTGATGAATCAACTGCCGAATAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(5-28)

Pilin (bacterial filament) (Pilin)

(36-166)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilE Neisseria gonorrhoeae strain FA1090

83.626

99.419

0.831
  pilE Neisseria gonorrhoeae MS11

77.193

99.419

0.767
  pilE Neisseria elongata subsp. glycolytica ATCC 29315

33.333

100

0.378
  pilA/pilA1 Eikenella corrodens VA1

35.556

100

0.372

Multiple sequence alignment