Detailed information NTG0032677

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: SPN23F_RS04600
• Genome accession: NC_011900
• Coordinates: 875397..876350 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae ATCC 700669
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 870397..881350

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPN23F_RS04575	rpmG	871140..871289 (+)	150	WP_001810029.1	50S ribosomal protein L33	-
SPN23F_RS04580 (SPN23F08980)	secG	871329..871562 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
SPN23F_RS04585 (SPN23F08990)	rnr	871664..874018 (+)	2355	WP_000654898.1	ribonuclease R	-
SPN23F_RS04590 (SPN23F09000)	smpB	873981..874448 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
SPN23F_RS04595 (SPN23F09010)	tehB	874464..875324 (+)	861	WP_000413762.1	SAM-dependent methyltransferase TehB	-
SPN23F_RS04600 (SPN23F09020)	coiA	875397..876350 (+)	954	WP_000495909.1	competence protein CoiA	Machinery gene
SPN23F_RS04605 (SPN23F09030)	pepF	876369..878171 (+)	1803	WP_000244125.1	oligoendopeptidase F	Regulator
SPN23F_RS04610 (SPN23F09040)	-	878173..878886 (+)	714	WP_000230399.1	O-methyltransferase	-
SPN23F_RS04615 (SPN23F09050)	prsA	878953..879894 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
SPN23F_RS04620 (SPN23F09060)	-	880011..880352 (-)	342	Protein_883	transposase	-
SPN23F_RS12930	-	880766..880861 (+)	96	Protein_884	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=32677 SPN23F_RS04600 WP_000495909.1 875397..876350(+) (coiA) [Streptococcus pneumoniae ATCC 700669]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=32677 SPN23F_RS04600 WP_000495909.1 875397..876350(+) (coiA) [Streptococcus pneumoniae ATCC 700669]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435