Detailed information NTG0325848

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: EGX70_RS08090
• Genome accession: NZ_CP033808
• Coordinates: 1546938..1548167 (-)
• Length: 409 a.a.
• NCBI ID: WP_000728357.1
• Uniprot ID: A0AAD2WWM9
• Organism: Streptococcus sp. FDAARGOS_522
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1541938..1553167

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EGX70_RS08065 (EGX70_08065)	-	1542049..1542246 (-)	198	WP_000285199.1	DUF951 domain-containing protein	-
EGX70_RS08070 (EGX70_08070)	-	1542256..1543148 (-)	893	Protein_1469	diacylglycerol kinase family protein	-
EGX70_RS08075 (EGX70_08075)	dnaN	1543206..1544342 (-)	1137	WP_000581132.1	DNA polymerase III subunit beta	-
EGX70_RS08080 (EGX70_08080)	dnaA	1544497..1545858 (-)	1362	WP_123948149.1	chromosomal replication initiator protein DnaA	-
EGX70_RS08085 (EGX70_08085)	spo0J	1546067..1546840 (-)	774	WP_000456084.1	ParB/RepB/Spo0J family partition protein	Regulator
EGX70_RS08090 (EGX70_08090)	htrA	1546938..1548167 (-)	1230	WP_000728357.1	S1C family serine protease	Regulator
EGX70_RS08095 (EGX70_08095)	rlmH	1548368..1548847 (+)	480	WP_000768333.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
EGX70_RS08115 (EGX70_08115)	-	1549426..1552005 (-)	2580	WP_000154429.1	YfhO family protein	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 43090.54 Da
• Isoelectric Point: 9.5271

>NTDB_id=325848 EGX70_RS08090 WP_000728357.1 1546938..1548167(-) (htrA) [Streptococcus sp. FDAARGOS_522]
MKKKLVSSLLKCSLIIIVSFAGGAFASFVMNHNDNIPNGGVTKTSKVNYNNITPTTKAVKKVQNSVVSVINYKQQESRSD
LSDFYSHFFGNQGGNTDKGLQVYGEGSGVIYKKDGKNAYVVTNNHVIDGAKQIEIQLADGSKAVGKLVGSDTYSDLAVVK
IPSDKVSNIAEFADSSKLNIGETAIAIGSPLGTEYANSVTQGIVSSLKRTVTMTNEEGQTVSTNAIQTDAAINPGNSGGA
LINIEGQVIGINSSKISSTSNQTSGQSSGNSVEGMGFAIPSNDVVKIINQLESNGQVERPALGISMAGLSNLPSDVISKL
KIPSNVTNGIVVASIQSGMPAQGKLKKYDVITKVDDKEVASPSDLQSLLYGHQVGDSITVTFYRGENKQTVTIKLTKTSK
DLAKQRANN

Nucleotide

• Length: 1230 bp

>NTDB_id=325848 EGX70_RS08090 WP_000728357.1 1546938..1548167(-) (htrA) [Streptococcus sp. FDAARGOS_522]
GTGAAAAAAAAATTAGTCTCATCACTTCTAAAGTGTTCTCTAATCATTATTGTTAGCTTTGCTGGTGGAGCATTTGCTAG
TTTTGTCATGAATCATAATGACAATATTCCAAATGGTGGTGTCACTAAAACTAGTAAAGTAAATTATAATAACATAACGC
CTACAACAAAAGCTGTTAAAAAGGTACAAAATAGTGTTGTTTCTGTTATCAATTATAAACAACAAGAGAGTCGTTCTGAC
CTATCAGACTTCTATAGTCATTTTTTTGGTAATCAGGGAGGCAACACTGATAAGGGCTTACAAGTTTACGGTGAAGGCTC
TGGAGTCATCTATAAAAAAGATGGTAAAAATGCCTATGTTGTCACTAATAACCACGTCATTGATGGGGCTAAACAAATTG
AAATTCAACTAGCCGATGGCTCAAAAGCAGTTGGGAAACTTGTTGGGTCAGATACCTACTCTGATTTAGCCGTCGTCAAA
ATTCCATCAGATAAAGTTTCAAATATTGCAGAATTTGCTGATTCATCAAAACTCAACATTGGTGAAACTGCTATAGCGAT
CGGAAGCCCTCTTGGAACTGAGTATGCAAATTCTGTAACTCAAGGTATTGTATCTAGTTTAAAAAGAACTGTAACAATGA
CTAATGAAGAAGGACAAACAGTTTCTACAAATGCTATCCAGACTGATGCTGCTATCAATCCTGGTAATTCAGGTGGAGCA
CTTATCAATATTGAAGGACAGGTTATTGGAATTAATTCTAGTAAAATTTCTTCTACATCAAATCAAACCTCAGGACAATC
GTCAGGAAATAGCGTTGAAGGTATGGGATTTGCCATTCCTTCAAATGATGTTGTTAAGATTATCAATCAACTTGAGAGTA
ACGGACAAGTAGAGAGACCTGCTCTAGGTATTTCTATGGCTGGATTAAGTAATTTACCATCCGATGTTATTAGTAAACTG
AAAATCCCAAGTAATGTTACTAATGGTATTGTAGTAGCATCTATCCAATCTGGCATGCCAGCTCAAGGCAAACTAAAGAA
ATACGATGTCATTACTAAAGTTGACGATAAAGAAGTAGCATCTCCAAGTGATTTACAAAGTTTACTCTATGGCCACCAGG
TAGGAGATTCCATAACAGTAACCTTTTATCGTGGTGAAAATAAACAAACAGTCACTATAAAACTTACTAAAACTAGTAAA
GATTTAGCTAAACAACGAGCAAATAACTAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (106-251)

• PDZ domain (PDZ_2) (300-395)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	63.359	96.088	0.609
htrA	Streptococcus gordonii str. Challis substr. CH1	57.357	98.044	0.562
htrA	Streptococcus mitis NCTC 12261	56.533	97.311	0.55
htrA	Streptococcus pneumoniae TIGR4	55.037	99.511	0.548
htrA	Streptococcus pneumoniae Rx1	55.037	99.511	0.548
htrA	Streptococcus pneumoniae D39	55.037	99.511	0.548
htrA	Streptococcus pneumoniae R6	55.037	99.511	0.548