Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   HAPS_RS07640 Genome accession   NC_011852
Coordinates   1553440..1554567 (-) Length   375 a.a.
NCBI ID   WP_015939837.1    Uniprot ID   B8F725
Organism   Glaesserella parasuis SH0165     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1548440..1559567
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HAPS_RS07620 (HAPS_1569) - 1549869..1550669 (-) 801 WP_015939835.1 ChaN family lipoprotein -
  HAPS_RS07625 (HAPS_1570) - 1550777..1551565 (-) 789 WP_010787335.1 heme ABC transporter ATP-binding protein -
  HAPS_RS07630 (HAPS_1571) - 1551565..1552551 (-) 987 WP_015939836.1 FecCD family ABC transporter permease -
  HAPS_RS07635 (HAPS_1572) - 1552551..1553387 (-) 837 WP_010787337.1 heme/hemin ABC transporter substrate-binding protein -
  HAPS_RS07640 (HAPS_1573) dprA 1553440..1554567 (-) 1128 WP_015939837.1 DNA-processing protein DprA Machinery gene
  HAPS_RS07645 (HAPS_1574) def 1554902..1555414 (+) 513 WP_005712670.1 peptide deformylase -
  HAPS_RS07650 (HAPS_1575) rfaD 1555426..1556352 (+) 927 WP_015939838.1 ADP-glyceromanno-heptose 6-epimerase -
  HAPS_RS12045 (HAPS_1576) - 1556444..1556587 (+) 144 WP_010787341.1 hypothetical protein -
  HAPS_RS11280 (HAPS_1577) - 1556568..1556852 (+) 285 WP_049753196.1 hypothetical protein -
  HAPS_RS11895 (HAPS_1578) - 1557656..1557814 (-) 159 WP_010787342.1 hypothetical protein -
  HAPS_RS07660 (HAPS_1579) - 1558035..1558427 (-) 393 WP_005713048.1 helix-turn-helix domain-containing protein -
  HAPS_RS07665 (HAPS_1580) - 1558455..1558724 (-) 270 WP_010787344.1 type II toxin-antitoxin system RelE family toxin -

Sequence

Protein


Download         Length: 375 a.a.        Molecular weight: 41737.82 Da        Isoelectric Point: 5.5989

>NTDB_id=32575 HAPS_RS07640 WP_015939837.1 1553440..1554567(-) (dprA) [Glaesserella parasuis SH0165]
MTHLTKLLALLQVPQLGAQRIGRLLSEVDFGEFCQYDKIALKQMGWNERQIQRWFNPEHKWIDQALQWAEQDQQRILTLF
DEDYPFLLKQISTAPPVLFVRGNVESLSLPQIAIVGSRDYSHYGEHWAGHFSAELVKHQLAVTSGLAIGIDGFCHQRAVN
ENGITIAVLGSGLDQVYPARHKKLAEQIVATSGALVSEFFPSQPPIAENFPRRNRIISGLSLGTLVIEATVNSGSLITAR
YALEQGREVFALPNSVQNPYSEGCHKLIKEGALLVENIDDILEAIAWQRQSVHIQPSLFDTKPKQAVKSEPKFAKNLPEL
TACQQQLFEQISLEPISIDDLAKATDMAVETALIELLNLELLGVVKQVSGGYVIT

Nucleotide


Download         Length: 1128 bp        

>NTDB_id=32575 HAPS_RS07640 WP_015939837.1 1553440..1554567(-) (dprA) [Glaesserella parasuis SH0165]
ATGACACATCTCACAAAATTATTAGCCCTGTTACAAGTGCCACAGCTTGGTGCACAACGTATCGGGCGGTTACTCTCGGA
AGTGGACTTTGGCGAATTTTGTCAATACGACAAAATCGCATTAAAGCAAATGGGCTGGAATGAACGGCAAATTCAGCGTT
GGTTTAATCCTGAGCATAAATGGATTGATCAGGCGTTGCAATGGGCGGAACAGGATCAGCAACGGATTTTAACTTTATTT
GACGAAGATTATCCTTTTTTACTGAAGCAGATCAGTACTGCTCCTCCAGTGCTTTTTGTGCGGGGGAATGTTGAAAGTTT
ATCGTTACCGCAGATAGCCATCGTTGGCAGTCGAGATTATTCCCACTATGGTGAACACTGGGCTGGGCATTTTTCGGCGG
AATTAGTGAAACATCAACTTGCTGTCACTAGTGGTTTAGCCATAGGCATAGACGGATTTTGTCATCAGCGTGCGGTCAAT
GAAAACGGGATTACTATTGCGGTTTTAGGCAGTGGTTTAGACCAAGTTTACCCTGCTCGCCATAAAAAACTTGCTGAACA
AATCGTTGCAACAAGCGGTGCGTTAGTGTCGGAATTTTTCCCTAGCCAGCCACCGATTGCTGAGAATTTTCCTAGACGAA
ATCGTATTATCAGCGGATTATCGCTCGGAACATTGGTTATTGAAGCAACAGTGAATAGTGGCTCGCTCATCACTGCTCGT
TATGCGTTAGAGCAAGGACGAGAAGTTTTTGCATTGCCGAACTCAGTACAAAACCCGTATAGCGAAGGGTGCCATAAATT
GATTAAAGAAGGGGCATTACTGGTTGAAAATATTGACGACATTTTAGAAGCGATTGCGTGGCAACGGCAATCAGTGCATA
TTCAACCAAGTCTATTTGATACGAAACCTAAACAAGCGGTGAAATCCGAACCCAAATTTGCAAAAAATCTACCTGAACTG
ACCGCTTGTCAGCAACAATTGTTTGAACAGATTAGCCTTGAGCCGATCAGCATTGATGATCTTGCCAAAGCGACGGATAT
GGCGGTAGAAACCGCATTGATTGAGCTGCTGAATTTGGAGTTGTTGGGTGTTGTGAAGCAGGTGAGTGGGGGGTATGTAA
TCACTTGA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(69-276)

DprA winged helix domain (DprA_WH)

(313-371)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B8F725

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Glaesserella parasuis strain SC1401

97.867

100

0.979
  dprA Haemophilus influenzae Rd KW20

53.235

90.667

0.483
  dprA Vibrio campbellii strain DS40M4

47.453

99.467

0.472
  dprA Vibrio cholerae strain A1552

44.415

100

0.445
  dprA Legionella pneumophila strain ERS1305867

39.153

100

0.395
  dprA Neisseria gonorrhoeae MS11

43.631

83.733

0.365

Multiple sequence alignment