Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   EGX73_RS01035 Genome accession   NZ_CP033740
Coordinates   132745..134052 (+) Length   435 a.a.
NCBI ID   WP_005470737.1    Uniprot ID   A0A6I4XEG1
Organism   Enterococcus sp. FDAARGOS_553     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 127745..139052
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGX73_RS01010 (EGX73_01015) - 127988..128791 (-) 804 WP_123866645.1 glucose PTS transporter subunit IIA -
  EGX73_RS01015 (EGX73_01020) - 128784..129860 (-) 1077 WP_123866646.1 PTS transporter subunit EIIC -
  EGX73_RS01020 (EGX73_01025) - 129985..130806 (+) 822 WP_003125834.1 MurR/RpiR family transcriptional regulator -
  EGX73_RS01025 (EGX73_01030) - 131089..131937 (-) 849 WP_117474433.1 hypothetical protein -
  EGX73_RS01030 (EGX73_01035) rlmH 131986..132465 (-) 480 WP_003125832.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  EGX73_RS01035 (EGX73_01040) htrA 132745..134052 (+) 1308 WP_005470737.1 S1C family serine protease Regulator
  EGX73_RS01040 (EGX73_01045) ytpR 134107..134718 (-) 612 WP_003125829.1 YtpR family tRNA-binding protein -
  EGX73_RS01045 (EGX73_01050) - 134930..135385 (-) 456 WP_005470736.1 universal stress protein -
  EGX73_RS01050 (EGX73_01055) - 135404..135718 (-) 315 WP_003125825.1 thioredoxin family protein -
  EGX73_RS01055 (EGX73_01060) pepA 135936..137012 (-) 1077 WP_003125824.1 glutamyl aminopeptidase -
  EGX73_RS01060 (EGX73_01065) - 137206..137550 (+) 345 WP_003125823.1 PepSY domain-containing protein -
  EGX73_RS01065 (EGX73_01070) - 137668..138711 (-) 1044 WP_029486526.1 hypothetical protein -

Sequence

Protein


Download         Length: 435 a.a.        Molecular weight: 44865.73 Da        Isoelectric Point: 4.3788

>NTDB_id=325305 EGX73_RS01035 WP_005470737.1 132745..134052(+) (htrA) [Enterococcus sp. FDAARGOS_553]
MVRKNVTPGRKPSSGLLKKLGIGILGGVVGGLLTFGGLYLAMGSSLTSPVTTATSGVQDNNGQTKVSNVKYDVNSDVTKA
VEKVQGAVVSIINLQQNNANGLEGLFGSGQQGGQGSGTENSGDDSSLEASSEGSGVIYKVDGDKAYIVTNNHVVEGQDGL
EVVLSDGTKVKAELVGTDAYTDLAVLRISSDKVDTVASFGDSDSLKVGEPAIAIGSPLGSSFANSVTQGIVSSLNRQVTN
QNESGEAVSINAIQTDAAINPGNSGGPLINVEGQVIGINSSKIASTSESTSSVSVEGMGFAIPSNDVVDIINQLEKDGKV
VRPALGIRTINLSSITSQQQEQILKVPSSVTDGVVVYSVNNATPAEQAGLKQYDVITKIDDTDISTTTDLQSALYKHKVG
DTITVTFYRGKEEKTAKVVLSVDTSINEQSTDSSN

Nucleotide


Download         Length: 1308 bp        

>NTDB_id=325305 EGX73_RS01035 WP_005470737.1 132745..134052(+) (htrA) [Enterococcus sp. FDAARGOS_553]
ATGGTACGAAAAAATGTGACACCAGGAAGAAAACCTTCTTCCGGCTTATTAAAAAAATTAGGTATTGGCATTCTTGGCGG
AGTAGTTGGTGGTTTGTTGACCTTCGGCGGACTTTATCTGGCGATGGGCTCTTCTTTGACTTCACCTGTAACGACCGCAA
CCAGCGGTGTTCAAGATAACAATGGACAAACGAAAGTCTCCAATGTTAAATATGACGTCAACAGCGATGTAACAAAAGCA
GTCGAAAAAGTGCAAGGAGCAGTCGTTTCGATCATCAACTTGCAACAAAATAATGCGAATGGCCTCGAAGGGTTATTTGG
CTCTGGTCAGCAAGGTGGTCAAGGATCAGGGACTGAGAATTCAGGCGATGACAGTTCACTAGAAGCTTCTTCTGAAGGAA
GTGGCGTGATTTATAAAGTAGATGGTGACAAAGCGTATATCGTTACGAATAACCACGTAGTAGAAGGACAAGATGGTTTG
GAAGTCGTTCTCTCTGATGGCACAAAAGTCAAAGCTGAATTAGTCGGAACAGACGCTTACACTGACCTTGCTGTTTTACG
CATCTCTTCTGATAAAGTAGACACGGTTGCTTCTTTCGGCGATTCTGATTCACTAAAAGTTGGCGAACCAGCAATTGCGA
TTGGTTCTCCATTAGGATCTAGCTTTGCAAATTCTGTAACGCAAGGGATTGTTTCTTCTCTGAATCGTCAAGTAACGAAT
CAAAATGAATCTGGTGAAGCAGTCAGCATCAATGCGATTCAAACAGATGCAGCGATCAACCCAGGAAACTCTGGTGGTCC
ACTGATCAACGTTGAAGGACAAGTGATCGGAATCAACTCTAGCAAGATCGCCAGCACTTCTGAATCAACATCAAGTGTCA
GCGTAGAAGGAATGGGCTTCGCGATCCCAAGTAACGACGTTGTCGATATTATCAACCAATTAGAAAAAGACGGCAAAGTT
GTTCGTCCAGCATTGGGTATTCGAACAATCAACTTAAGCTCAATCACTTCGCAACAACAAGAACAAATCTTGAAAGTACC
ATCTTCTGTCACTGACGGAGTAGTCGTATACTCAGTAAATAACGCGACACCAGCTGAACAAGCAGGATTGAAACAATACG
ATGTCATCACGAAAATCGATGATACCGACATCAGCACAACCACAGATCTACAATCTGCACTGTACAAGCACAAAGTCGGT
GATACGATCACAGTGACGTTCTACCGCGGCAAAGAAGAAAAAACAGCCAAAGTCGTTCTATCTGTAGATACTTCGATCAA
TGAACAATCGACTGACAGCAGCAACTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(323-419)

Peptidase family M50 (Peptidase_M50)

(263-421)

Trypsin-like peptidase domain (Trypsin_2)

(133-278)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6I4XEG1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

55.528

91.494

0.508
  htrA Streptococcus gordonii str. Challis substr. CH1

50.827

97.241

0.494
  htrA Streptococcus mitis NCTC 12261

54.377

86.667

0.471
  htrA Streptococcus pneumoniae TIGR4

55.682

80.92

0.451
  htrA Streptococcus pneumoniae Rx1

55.682

80.92

0.451
  htrA Streptococcus pneumoniae D39

55.682

80.92

0.451
  htrA Streptococcus pneumoniae R6

55.682

80.92

0.451

Multiple sequence alignment