Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   D8N35_RS16075 Genome accession   NZ_CP032739
Coordinates   3272502..3273806 (+) Length   434 a.a.
NCBI ID   WP_121262003.1    Uniprot ID   -
Organism   Enterococcus casseliflavus strain EC-369     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3267502..3278806
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D8N35_RS16035 (D8N35_16035) - 3267503..3267766 (-) 264 WP_086316420.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
  D8N35_RS16040 (D8N35_16040) - 3268052..3268171 (-) 120 WP_231435831.1 hypothetical protein -
  D8N35_RS16045 (D8N35_16045) - 3268559..3268657 (-) 99 WP_121261997.1 type I toxin-antitoxin system Fst family toxin -
  D8N35_RS16050 (D8N35_16050) map 3268745..3269503 (-) 759 WP_121261999.1 type I methionyl aminopeptidase -
  D8N35_RS16055 (D8N35_16055) truA 3269546..3270283 (-) 738 WP_121262001.1 tRNA pseudouridine(38-40) synthase TruA -
  D8N35_RS18615 - 3270348..3270494 (-) 147 WP_205589238.1 hypothetical protein -
  D8N35_RS18330 - 3270540..3271439 (-) 900 WP_205589239.1 EVE domain-containing protein -
  D8N35_RS16070 (D8N35_16070) rlmH 3271649..3272128 (-) 480 WP_008379108.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  D8N35_RS16075 (D8N35_16075) htrA 3272502..3273806 (+) 1305 WP_121262003.1 S1C family serine protease Regulator
  D8N35_RS16080 (D8N35_16080) ytpR 3273875..3274489 (-) 615 WP_121262005.1 YtpR family tRNA-binding protein -
  D8N35_RS16085 (D8N35_16085) - 3275041..3275502 (-) 462 WP_121262007.1 universal stress protein -
  D8N35_RS16090 (D8N35_16090) - 3275515..3275835 (-) 321 WP_026008043.1 thioredoxin family protein -
  D8N35_RS16095 (D8N35_16095) pepA 3275965..3277041 (-) 1077 WP_121262334.1 glutamyl aminopeptidase -
  D8N35_RS16105 (D8N35_16105) - 3277334..3277678 (+) 345 WP_005234590.1 peptidase -
  D8N35_RS16110 (D8N35_16110) - 3277739..3278773 (-) 1035 WP_121262009.1 hypothetical protein -

Sequence

Protein


Download         Length: 434 a.a.        Molecular weight: 44872.38 Da        Isoelectric Point: 4.0740

>NTDB_id=318429 D8N35_RS16075 WP_121262003.1 3272502..3273806(+) (htrA) [Enterococcus casseliflavus strain EC-369]
MARKYVTPGKKTSPGLLKRLGIGILGGMVGGLLTFGGLYLAMGSSLTSTPETTTNSGVQDSNGQTQVSNVKLDVTSDVTE
AVEKVQDSVVSIINLQQSQSNDWNSLFGQHGGQSEGDSQSDDDSALEASSEGSGVIYKIDGDDAYVVTNNHVVEGQDGLE
VVLADGTKVKAELVGTDAYTDLAVLKISSEHVKTAATFGDSSALKVGEPAIAIGSPLGSDYANSVTQGIVSSLNRQVTSQ
NESGGTISINAIQTDAAINPGNSGGPLINVDGQVIGINSSKIASTSGSASGVSVEGMGFAIPSNDVVEIINQLEADGKVV
RPALGIQTIDLGSITSQQQEQILKVPSSVTSGVVIYSVNNATPAEQAGLQQYDVITKIDDTEVSTTTDLQSALYKHKVGD
TITVTFYRGDEEKTAEVKLSVDTSINEQSTDSSN

Nucleotide


Download         Length: 1305 bp        

>NTDB_id=318429 D8N35_RS16075 WP_121262003.1 3272502..3273806(+) (htrA) [Enterococcus casseliflavus strain EC-369]
ATGGCAAGAAAATATGTCACACCAGGCAAGAAAACTTCTCCTGGTTTATTAAAACGATTAGGTATTGGGATTTTAGGCGG
TATGGTCGGCGGTTTATTGACCTTCGGCGGTCTGTATCTGGCAATGGGTTCCTCTTTGACTTCAACACCAGAAACCACGA
CCAACAGCGGGGTCCAAGATTCTAACGGACAAACCCAAGTATCCAATGTAAAACTTGATGTGACTAGCGATGTCACTGAG
GCAGTTGAAAAAGTACAAGATTCTGTCGTTTCCATCATTAATCTACAACAAAGTCAAAGCAACGATTGGAACAGCCTCTT
TGGTCAGCACGGCGGACAAAGTGAAGGCGATAGCCAAAGCGACGACGACAGTGCTTTAGAAGCTTCTTCTGAAGGGAGTG
GGGTCATCTACAAAATCGATGGCGACGATGCCTATGTTGTAACCAACAACCACGTCGTAGAAGGTCAAGACGGTTTAGAA
GTTGTTTTAGCAGACGGTACGAAAGTCAAAGCTGAATTGGTCGGTACTGACGCTTACACAGACTTGGCTGTATTGAAAAT
CTCTTCAGAGCATGTGAAGACTGCCGCAACATTTGGTGATTCAAGTGCCTTGAAAGTCGGCGAACCAGCAATCGCAATCG
GCTCTCCTCTCGGCTCTGACTACGCAAACTCTGTGACACAAGGGATCGTTTCTTCCTTGAATCGTCAAGTAACAAGCCAA
AACGAATCTGGTGGTACGATCAGCATCAATGCGATCCAAACGGATGCTGCGATCAACCCAGGGAACTCAGGTGGTCCACT
GATCAACGTTGATGGTCAAGTGATTGGGATCAACTCAAGTAAAATCGCCAGCACCTCTGGCTCCGCTTCAGGTGTTAGTG
TCGAAGGGATGGGCTTTGCGATCCCAAGTAACGATGTCGTTGAAATCATCAATCAACTAGAAGCAGACGGCAAAGTGGTT
CGCCCTGCACTAGGTATCCAAACGATCGATTTAGGTTCCATCACATCACAACAACAAGAACAAATCTTGAAAGTTCCTTC
ATCCGTAACTTCTGGCGTTGTGATCTACTCAGTCAACAATGCAACACCAGCAGAACAAGCAGGATTGCAACAATATGACG
TTATTACGAAGATCGATGATACAGAAGTCAGCACAACAACGGATCTACAATCTGCGTTGTACAAACACAAAGTCGGTGAC
ACGATCACTGTAACCTTCTATCGTGGCGATGAAGAAAAAACGGCAGAAGTAAAACTTTCCGTTGATACGTCGATCAACGA
ACAATCAACAGACAGCAGCAACTAA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(19-420)

Trypsin-like peptidase domain (Trypsin_2)

(132-277)

PDZ domain (PDZ_2)

(322-419)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

56.171

91.475

0.514
  htrA Streptococcus gordonii str. Challis substr. CH1

51.074

96.544

0.493
  htrA Streptococcus mitis NCTC 12261

55.432

82.719

0.459
  htrA Streptococcus pneumoniae TIGR4

57.018

78.802

0.449
  htrA Streptococcus pneumoniae Rx1

57.018

78.802

0.449
  htrA Streptococcus pneumoniae D39

57.018

78.802

0.449
  htrA Streptococcus pneumoniae R6

57.018

78.802

0.449

Multiple sequence alignment