Detailed information NTG0318156

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: D7321_RS02895
• Genome accession: NZ_CP032680
• Coordinates: 618089..620248 (+)
• Length: 719 a.a.
• NCBI ID: WP_127835554.1
• Uniprot ID: A0A9W4E7V5
• Organism: Lactobacillus johnsonii strain ZLJ010
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 613089..625248

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D7321_RS02865 (D7321_02865)	-	613097..613324 (+)	228	WP_011161705.1	hypothetical protein	-
D7321_RS02870 (D7321_02870)	udk	613351..613986 (-)	636	WP_004895448.1	uridine kinase	-
D7321_RS02875 (D7321_02875)	-	614315..614470 (+)	156	WP_127835551.1	lactacin F inducer peptide precursor	-
D7321_RS02880 (D7321_02880)	-	614473..615780 (+)	1308	WP_127835552.1	GHKL domain-containing protein	-
D7321_RS02885 (D7321_02885)	-	615924..617081 (+)	1158	WP_127835553.1	RNA-guided endonuclease TnpB family protein	-
D7321_RS02890 (D7321_02890)	-	617279..618076 (+)	798	WP_014567245.1	LytTR family DNA-binding domain-containing protein	-
D7321_RS02895 (D7321_02895)	comA	618089..620248 (+)	2160	WP_127835554.1	peptide cleavage/export ABC transporter	Regulator
D7321_RS02900 (D7321_02900)	-	620259..620851 (+)	593	Protein_568	hypothetical protein	-
D7321_RS02905 (D7321_02905)	-	620896..621180 (+)	285	WP_127835555.1	bacteriocin immunity protein	-
D7321_RS02910 (D7321_02910)	-	621310..621543 (+)	234	WP_127835556.1	hypothetical protein	-
D7321_RS02915 (D7321_02915)	-	621587..621862 (+)	276	WP_127835557.1	hypothetical protein	-
D7321_RS02925 (D7321_02925)	-	622067..622297 (+)	231	WP_094497872.1	hypothetical protein	-
D7321_RS02930 (D7321_02930)	-	622421..622735 (+)	315	WP_004896933.1	bacteriocin immunity protein	-
D7321_RS02935 (D7321_02935)	-	622738..623022 (+)	285	WP_127835558.1	hypothetical protein	-

Sequence

Protein

• Length: 719 a.a.
• Molecular weight: 81109.33 Da
• Isoelectric Point: 7.1584

>NTDB_id=318156 D7321_RS02895 WP_127835554.1 618089..620248(+) (comA) [Lactobacillus johnsonii strain ZLJ010]
MLFKYKSVYVPQVDEMDCGVACLAMILKQYHSRISLAHLRHEARTNLEGTTALGLVKTAQKFNFKTEAVKADMSLFNEDS
IQYPFIVHVLKQGELLHYYVVLKNTKHYLVIADPDPSVGVIKMPKDRFAQEWTGIALFMVPNENFEPIKEKKNNLWSLFP
YMFKQKRLMINIILAALLMTIISICSSYFVQGIIDTYIPDGTYQTLSILAVGLLIAYIFNSIFSYGQNFLLNVLGQRLSI
DLNLQYIRHIFELPMEFFVTRRTGEITSRFSDASRIIDALASTVISLFLDLAIVIVMGIVLAAQNMTLFGITLLALPVYA
VVILGFTKKFEKLNDEQMESNAVLSSSVIEDIQGIETIKALNSEDTRYRRIDSQFVNYLKKSFKYSKAESLQTALKTFIQ
LSLNVIILWVGARVVIQGQMSIGQLMTFNALLSYFIDPLQNIINLQPRLQSASVAQNRLNEVYQVQSEFNADTSIQNSAA
LEGMIEYKHVHYRYGYGTDVLKNINLKIKPDEKLAIVGMSGSGKSTMVKLLVDFFSPSKGEVTLNGHATSEVNKHTLRSY
VNYVPQTPYIFSGTVKENLLLGCRPDISEEDVIKACQIAGIDQEIASLPLQFETKLDENAKILSGGQKQRLTIARALLSP
AKVFIFDEVTSGLDTITEKRVVDNLMKLKDKTIIFIAHRLAIAERADKVVVIDQGQIVEEGSHEELMEQHGFYYDLVKG

Nucleotide

• Length: 2160 bp

>NTDB_id=318156 D7321_RS02895 WP_127835554.1 618089..620248(+) (comA) [Lactobacillus johnsonii strain ZLJ010]
ATGTTATTCAAATATAAATCTGTTTATGTACCTCAAGTAGATGAGATGGATTGCGGAGTTGCTTGTTTAGCGATGATCTT
AAAACAATATCATTCTCGTATATCTTTAGCTCATTTACGTCATGAAGCGCGTACTAATCTTGAAGGTACAACTGCGCTGG
GACTAGTTAAAACAGCACAGAAATTTAATTTTAAAACTGAAGCCGTAAAAGCTGATATGTCTCTTTTTAATGAGGATAGT
ATTCAATACCCTTTTATTGTGCATGTTCTTAAGCAAGGAGAATTACTTCATTATTACGTAGTTCTTAAAAATACTAAGCA
TTACTTAGTAATTGCCGACCCAGATCCTTCAGTTGGTGTGATAAAAATGCCTAAAGATAGGTTCGCTCAAGAATGGACAG
GGATTGCACTCTTTATGGTTCCCAATGAAAACTTTGAACCAATTAAAGAAAAGAAAAATAACCTATGGTCTCTCTTTCCA
TATATGTTTAAGCAAAAGCGGCTGATGATTAATATCATTTTAGCCGCTTTATTAATGACAATAATTAGTATTTGTAGTTC
ATACTTTGTGCAAGGAATAATCGATACTTATATTCCCGATGGAACTTATCAGACTCTTTCAATTTTAGCTGTTGGACTAT
TAATTGCTTATATTTTTAATTCAATCTTTTCTTATGGACAGAATTTTTTATTAAATGTTCTAGGTCAAAGATTAAGTATT
GATTTAAACCTCCAATATATAAGGCATATTTTTGAATTGCCAATGGAATTCTTTGTGACTAGAAGAACTGGTGAAATAAC
CTCACGTTTCTCTGATGCAAGTAGAATTATTGATGCTCTAGCAAGTACTGTTATTTCACTTTTCTTAGACTTAGCGATTG
TAATTGTAATGGGAATAGTGTTAGCTGCTCAAAATATGACTTTATTTGGAATCACATTATTAGCTTTACCAGTATATGCT
GTAGTAATTCTGGGATTTACTAAGAAATTTGAAAAGTTAAATGATGAACAAATGGAGAGCAATGCAGTACTAAGTTCTTC
AGTCATCGAAGATATTCAAGGTATTGAAACTATCAAAGCTCTCAATAGTGAAGATACAAGATATCGTAGAATCGATAGCC
AATTTGTAAATTATTTAAAGAAGTCATTTAAATATAGTAAGGCTGAGAGTTTGCAGACGGCGTTAAAGACATTTATTCAA
CTATCTCTTAATGTAATTATTTTATGGGTTGGCGCACGAGTAGTGATACAAGGACAGATGAGTATCGGTCAATTAATGAC
TTTTAATGCATTACTATCTTATTTCATTGACCCACTTCAAAATATTATTAACTTACAACCTCGTCTTCAATCAGCTAGTG
TTGCACAAAATAGATTGAACGAGGTTTATCAGGTGCAAAGTGAATTTAATGCAGATACTTCTATCCAGAACTCAGCTGCT
TTAGAAGGAATGATTGAATACAAGCATGTTCATTATCGATATGGTTATGGGACGGATGTTTTAAAAAACATTAATCTAAA
AATTAAGCCAGATGAAAAATTAGCAATTGTTGGCATGAGTGGATCAGGAAAATCGACAATGGTTAAGTTACTCGTTGATT
TCTTTTCACCAAGTAAGGGAGAAGTAACTTTAAATGGTCATGCAACTAGTGAAGTTAATAAACATACCTTACGCTCATAT
GTTAACTATGTTCCTCAAACGCCATATATCTTTTCTGGAACAGTTAAGGAGAATTTATTACTCGGCTGCAGACCGGATAT
TAGCGAAGAAGATGTAATTAAAGCCTGTCAGATTGCTGGAATTGATCAGGAGATAGCTAGTTTGCCACTACAATTCGAGA
CAAAGTTAGATGAGAATGCCAAGATTTTATCCGGTGGACAAAAGCAGAGATTAACTATTGCTAGAGCATTACTCTCGCCA
GCAAAAGTTTTTATCTTTGATGAAGTAACAAGTGGCTTAGATACAATTACAGAAAAAAGAGTAGTTGACAATCTTATGAA
ACTAAAAGACAAGACAATCATTTTTATTGCACACCGTCTAGCCATTGCAGAACGTGCAGATAAGGTGGTTGTAATTGACC
AGGGGCAGATTGTTGAAGAAGGAAGTCATGAAGAGCTTATGGAGCAACATGGTTTTTATTATGACTTAGTAAAGGGATAG

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (169-439)

• ABC transporter (ABC_tran) (501-651)

• Peptidase C39 family (Peptidase_C39) (7-143)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	56.601	99.026	0.56
comA	Streptococcus mitis SK321	56.32	99.026	0.558
comA	Streptococcus pneumoniae Rx1	56.32	99.026	0.558
comA	Streptococcus pneumoniae D39	56.32	99.026	0.558
comA	Streptococcus pneumoniae R6	56.32	99.026	0.558
comA	Streptococcus pneumoniae TIGR4	56.18	99.026	0.556
comA	Streptococcus gordonii str. Challis substr. CH1	55.478	99.026	0.549
comA/nlmT	Streptococcus mutans UA159	53.465	98.331	0.526