Detailed information NTG0317472

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: CFM84_RS13140
• Genome accession: NZ_CP032637
• Coordinates: 2489462..2491654 (+)
• Length: 730 a.a.
• NCBI ID: WP_129533378.1
• Uniprot ID: -
• Organism: Lacticaseibacillus paracasei strain ZFM54
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 2484462..2496654

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CFM84_RS13115 (CFM84_13115)	-	2485170..2485349 (+)	180	WP_013246044.1	bacteriocin	-
CFM84_RS13120 (CFM84_13120)	-	2485657..2485839 (+)	183	WP_020751751.1	hypothetical protein	-
CFM84_RS13125 (CFM84_13125)	-	2486016..2486438 (+)	423	WP_032800967.1	hypothetical protein	-
CFM84_RS13130 (CFM84_13130)	-	2486740..2487546 (-)	807	WP_013246042.1	LytTR family DNA-binding domain-containing protein	-
CFM84_RS13135 (CFM84_13135)	-	2487551..2488849 (-)	1299	WP_013246041.1	GHKL domain-containing protein	-
CFM84_RS16010	-	2489019..2489174 (+)	156	WP_013246040.1	bacteriocin-like peptide, LSEI_2386 family	-
CFM84_RS13140 (CFM84_13140)	comA	2489462..2491654 (+)	2193	WP_129533378.1	peptide cleavage/export ABC transporter	Regulator
CFM84_RS13145 (CFM84_13145)	-	2491665..2493044 (+)	1380	WP_013246038.1	bacteriocin secretion accessory protein	-
CFM84_RS13150 (CFM84_13150)	-	2493218..2493568 (+)	351	WP_003567340.1	hypothetical protein	-
CFM84_RS13155 (CFM84_13155)	-	2493641..2493952 (+)	312	WP_013246036.1	hypothetical protein	-
CFM84_RS13160 (CFM84_13160)	-	2494258..2495613 (+)	1356	WP_013246035.1	threonine/serine exporter ThrE family protein	-
CFM84_RS13165 (CFM84_13165)	-	2495718..2496014 (+)	297	WP_013246034.1	bacteriocin immunity protein	-
CFM84_RS13170 (CFM84_13170)	-	2496207..2496491 (+)	285	WP_003580845.1	bacteriocin immunity protein	-

Sequence

Protein

• Length: 730 a.a.
• Molecular weight: 81302.51 Da
• Isoelectric Point: 7.0226

>NTDB_id=317472 CFM84_RS13140 WP_129533378.1 2489462..2491654(+) (comA) [Lacticaseibacillus paracasei strain ZFM54]
MIKYNLKLGQAQYYKRYYTPQVDERDCGVAALNMLLQFNGSDYSLAHLRQLAKTDQEGTTALGIVRAAQALHFETKAVKA
DMTLFDLDDVPYPFLVHVLKRGELLHYYVVFKATKDHILIGDPDPSVAMTWLPKDRFAKEWSGVAIFIAPEPQYQPRKED
KGSLFAFVPMLARQKGIIANIIVAAVLITLISIVGSYFLQSIIDTYIPNGMRTTLGMIATGLILAYVLQSVLTYGQNFLM
AVLGQRLSIDVILGYVRHLYELPMSFFSTRRTGEIVSRFSDANKIIDALANTIMTLFLDIWIVLILGIVLGIQNTTLFLV
SLIAVPCYLVIVFAFQRPFNRLNQETMESNAILSSSIIEDLNGIETIKSLTGEKVSYERVDREFVTYLKKSFNYTKADQL
QQAIKGLLKLVLNVVVLWIGASLVMANKMSLGQMLTFNALLAYFTNPLESIINLQPKLQMAKVVNNRLNEVYLVESEFKE
QRSLNDRHLIDGAINVTDVSFKYGFGQDVLKQINLEIPENAKYTIVGMSGSGKSTLAKLLVGFYPVDTGKGKITFNGVPI
SDVDLTTLRQYIEYVPQDPFIFSGSVIENLTLGSRSNITEADIEAACSVAEIAGDISNLPQIWQTKLSESGSILSGGQKQ
RLAIARALLSPAKVLIFDESTSSLDTITERKIVDRLLAMTDRTIIFVAHRLTIAAKTEQIVVMDHGAIVEQGNHAELSAK
QGYYARLVSE

Nucleotide

• Length: 2193 bp

>NTDB_id=317472 CFM84_RS13140 WP_129533378.1 2489462..2491654(+) (comA) [Lacticaseibacillus paracasei strain ZFM54]
ATGATCAAATACAACCTAAAGCTCGGCCAAGCACAGTATTACAAGCGTTACTACACGCCTCAGGTGGATGAGCGCGATTG
CGGGGTTGCGGCGCTTAATATGCTGCTGCAATTTAATGGCTCGGATTATTCGCTAGCGCATCTGCGACAGTTAGCGAAGA
CGGATCAGGAAGGAACAACAGCGTTAGGGATTGTCCGCGCTGCTCAGGCGCTTCATTTTGAAACCAAGGCTGTCAAGGCG
GATATGACGCTGTTTGATCTTGATGATGTTCCTTATCCGTTTCTTGTCCATGTTTTGAAGCGTGGCGAGTTGCTTCATTA
TTATGTCGTGTTTAAGGCGACAAAGGATCATATATTGATTGGCGATCCTGATCCATCAGTAGCGATGACCTGGCTTCCCA
AAGATCGCTTTGCGAAGGAGTGGTCGGGGGTCGCTATTTTTATTGCACCAGAACCGCAATATCAACCACGCAAAGAGGAC
AAAGGCAGTCTCTTTGCGTTTGTGCCGATGCTAGCGCGACAAAAAGGGATCATTGCCAATATTATTGTCGCCGCTGTGTT
GATCACGTTGATTAGTATTGTCGGGTCTTATTTTCTTCAGTCGATTATTGATACTTATATTCCAAACGGGATGCGCACAA
CTTTGGGAATGATTGCCACTGGTCTCATCCTTGCTTATGTCCTGCAGTCGGTTTTAACCTATGGGCAAAATTTTTTGATG
GCTGTTTTAGGACAGCGTTTGTCGATTGATGTCATTTTGGGTTACGTTAGGCATCTTTATGAATTACCGATGTCCTTCTT
TTCCACGCGTCGGACTGGGGAAATTGTGTCGCGGTTTTCCGATGCTAATAAGATTATTGATGCGCTGGCAAACACGATTA
TGACCTTGTTTCTTGATATTTGGATTGTCTTAATTTTAGGGATCGTGTTAGGCATTCAAAACACCACCTTATTCTTGGTG
TCTTTAATTGCTGTGCCTTGTTATTTGGTGATTGTGTTCGCTTTTCAGCGGCCATTTAATCGACTGAATCAAGAGACGAT
GGAAAGCAATGCCATTTTGAGTTCATCCATTATCGAGGATTTGAACGGGATTGAGACGATTAAATCACTGACCGGTGAGA
AAGTCAGTTATGAACGGGTTGACCGTGAATTCGTCACTTATTTGAAAAAGTCGTTCAATTATACAAAAGCTGATCAACTG
CAGCAGGCGATCAAGGGACTGCTGAAGTTGGTTTTGAATGTGGTCGTGCTGTGGATTGGTGCGAGTTTGGTGATGGCTAA
CAAGATGAGTCTAGGACAGATGCTGACGTTCAATGCGTTGTTGGCATATTTCACTAATCCGTTAGAAAGCATCATTAATT
TGCAACCAAAATTGCAAATGGCCAAAGTCGTGAATAACCGGCTGAATGAAGTGTATTTGGTTGAATCGGAGTTTAAAGAA
CAGCGAAGTTTGAATGATCGGCATTTAATTGATGGCGCTATCAATGTGACCGATGTGTCCTTTAAGTATGGTTTTGGGCA
AGATGTTTTGAAGCAAATCAATCTTGAAATCCCGGAGAATGCCAAATACACCATTGTCGGCATGAGTGGATCAGGGAAAT
CGACCTTAGCCAAGTTGCTAGTAGGTTTCTATCCAGTGGACACTGGCAAAGGGAAAATCACATTTAATGGGGTTCCAATC
AGTGATGTTGATCTAACAACGTTACGACAATATATCGAGTATGTACCACAAGATCCGTTTATTTTTTCTGGCTCAGTCAT
TGAAAACTTAACGTTGGGTAGCCGTTCGAATATCACTGAAGCCGATATTGAAGCTGCCTGTTCAGTGGCAGAAATTGCCG
GAGATATTTCGAATTTGCCGCAGATATGGCAGACCAAACTTTCTGAAAGCGGCAGTATTTTATCGGGTGGACAAAAGCAG
CGACTAGCAATTGCCCGAGCGTTATTATCACCGGCAAAAGTGTTGATTTTTGATGAATCGACCAGCAGTTTAGATACGAT
CACCGAGCGAAAAATTGTTGATCGGTTGTTAGCGATGACTGATCGAACCATTATTTTTGTGGCTCATCGGCTGACCATTG
CTGCTAAAACGGAACAGATTGTGGTCATGGATCATGGTGCGATTGTTGAACAAGGAAATCATGCTGAGTTATCGGCCAAA
CAAGGCTATTATGCTCGGTTGGTAAGTGAGTGA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (510-662)

• Peptidase C39 family (Peptidase_C39) (16-152)

• ABC transporter transmembrane region (ABC_membrane) (180-448)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	58.496	98.356	0.575
comA	Streptococcus pneumoniae Rx1	57.939	98.356	0.57
comA	Streptococcus pneumoniae D39	57.939	98.356	0.57
comA	Streptococcus pneumoniae R6	57.939	98.356	0.57
comA	Streptococcus mitis SK321	57.799	98.356	0.568
comA	Streptococcus pneumoniae TIGR4	57.521	98.356	0.566
comA	Streptococcus gordonii str. Challis substr. CH1	56.825	98.356	0.559
comA/nlmT	Streptococcus mutans UA159	54.571	98.904	0.54