Detailed information NTG0317303

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: D7I46_RS06700
• Genome accession: NZ_CP032627
• Coordinates: 1434329..1436572 (-)
• Length: 747 a.a.
• NCBI ID: WP_120772198.1
• Uniprot ID: A0A387BIT3
• Organism: Lactococcus allomyrinae strain 1JSPR-7
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1429329..1441572

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D7I46_RS06670 (D7I46_06670)	atpA	1429770..1430800 (-)	1031	Protein_1321	F0F1 ATP synthase subunit alpha	-
D7I46_RS06675 (D7I46_06675)	-	1430815..1431342 (-)	528	WP_120772194.1	F0F1 ATP synthase subunit delta	-
D7I46_RS06680 (D7I46_06680)	atpF	1431410..1431916 (-)	507	WP_120772195.1	F0F1 ATP synthase subunit B	-
D7I46_RS06685 (D7I46_06685)	atpB	1431931..1432644 (-)	714	WP_120772196.1	F0F1 ATP synthase subunit A	-
D7I46_RS06690 (D7I46_06690)	-	1432690..1432896 (-)	207	WP_120772197.1	F0F1 ATP synthase subunit C	-
D7I46_RS06695 (D7I46_06695)	-	1433135..1433917 (-)	783	WP_120773311.1	alpha/beta hydrolase	-
D7I46_RS06700 (D7I46_06700)	comEC	1434329..1436572 (-)	2244	WP_120772198.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
D7I46_RS06705 (D7I46_06705)	comEA	1436553..1437209 (-)	657	WP_120772199.1	helix-hairpin-helix domain-containing protein	Machinery gene
D7I46_RS06710 (D7I46_06710)	-	1437321..1438712 (-)	1392	WP_120772200.1	ABC transporter permease	-
D7I46_RS06715 (D7I46_06715)	-	1438709..1439665 (-)	957	WP_120772201.1	ABC transporter ATP-binding protein	-
D7I46_RS06720 (D7I46_06720)	-	1439924..1440451 (-)	528	WP_120772202.1	hypothetical protein	-
D7I46_RS06725 (D7I46_06725)	-	1440452..1440652 (-)	201	WP_120772203.1	helix-turn-helix transcriptional regulator	-
D7I46_RS06730 (D7I46_06730)	-	1440771..1441178 (-)	408	WP_120772204.1	hypothetical protein	-

Sequence

Protein

• Length: 747 a.a.
• Molecular weight: 84570.48 Da
• Isoelectric Point: 9.6192

>NTDB_id=317303 D7I46_RS06700 WP_120772198.1 1434329..1436572(-) (comEC) [Lactococcus allomyrinae strain 1JSPR-7]
MLSVLTKFPLIFLAYLAVLLYYCIFDFNSLIALAFACSLGIALYRKYFLLFPILLVLTGFFFIVSIDNHQKMITQAQNVS
QIKIIPDSIQVNGDLLSFQGNEAGKKYQVYDTLQSEKEKKFYENLRQNCTISFTGNLEVPEHQRNFNGFDEQKYLATQGI
YREIIVTSISKIKTNRGLDLHVLRRSAIVWIQSHFPKPMSNYMTGLLFGYLDKDFEQMGDIYSSLGIIHLFALSGMQVNF
FIDGLRKILLRLGIRRDIVDILQVPFSIIYAFLTGLSVSILRALFQKNIKLTGLDNIALTTLILMFVSPKFLLTAGGQLT
LFYAFAISMLSHLFISKKESLTEKIHLTSKLKQVIIASSALSLLVLPVLIFNFYIFQPLSILLTIGFGMLFDLILLPLLL
TVFLLSLTGLTLNLNWMFKTLEALVQLVDCPFHYPLVLGKPNAIQLILLLSITALLLDFWMQKKLRWLLLCSLFIIFFTC
KNPSQPTITAVDVGQGDSIFLKDRFNKQTILIDTGGRLNIPEKSWQKAQTESNASKTLIPYLESEGVSQIDQLILTHTDD
DHVGDFLNLADKIKIKEVWVSPGELTCPDFVGKLKKAKIPIHLTQVGDEIPIFNSQLQVLSNGYTGKGDNNDSIVTYGNF
YGKKFLFTGDLEQDGEMKLLKNYPNLKVDILKAGHHGSKTSSNPKFIKQIQPQLAIISVGKNNHYGHPNQQTLDTFKKYK
VKSLRTDQNGAIKLTEIKGIWRISTVR

Nucleotide

• Length: 2244 bp

>NTDB_id=317303 D7I46_RS06700 WP_120772198.1 1434329..1436572(-) (comEC) [Lactococcus allomyrinae strain 1JSPR-7]
ATTCTATCTGTGTTGACTAAGTTTCCTTTGATATTTTTAGCATATTTAGCAGTTTTGCTTTATTATTGCATTTTTGATTT
TAATTCATTAATAGCACTAGCCTTTGCCTGTTCGCTGGGTATAGCATTGTATAGAAAATATTTCCTGCTTTTTCCAATTT
TATTGGTGCTGACAGGTTTTTTCTTCATTGTCAGCATTGACAACCATCAAAAAATGATAACTCAAGCTCAAAACGTTTCC
CAAATCAAGATTATTCCTGACAGTATTCAAGTAAATGGTGATTTGCTCAGTTTTCAGGGAAATGAAGCTGGTAAAAAATA
TCAAGTTTATGACACACTCCAATCAGAAAAAGAGAAAAAATTTTATGAGAATCTAAGACAAAATTGCACAATAAGTTTCA
CAGGAAACCTTGAAGTTCCAGAGCATCAAAGAAATTTTAATGGTTTTGATGAACAAAAATATCTTGCAACACAAGGAATT
TACAGAGAAATCATCGTTACATCTATCTCGAAAATCAAAACAAATCGAGGGCTTGACTTACACGTACTACGAAGAAGCGC
AATTGTTTGGATACAAAGTCATTTCCCCAAACCTATGTCAAACTATATGACAGGACTGCTTTTTGGGTATCTTGATAAAG
ATTTTGAGCAAATGGGTGATATTTATAGTTCACTTGGGATTATCCATTTATTTGCATTGTCAGGGATGCAAGTTAATTTT
TTTATTGATGGCTTGCGAAAAATATTGCTACGTTTGGGAATACGACGAGATATTGTGGATATCCTCCAAGTTCCTTTTTC
AATTATCTATGCTTTTTTGACAGGTTTATCAGTATCAATTCTTCGCGCACTTTTTCAAAAAAATATTAAATTGACAGGTT
TAGACAATATTGCTCTAACCACACTTATTTTAATGTTTGTAAGTCCCAAATTTTTACTGACAGCAGGTGGTCAGCTCACT
CTATTTTACGCATTTGCTATCAGTATGCTATCACATTTATTCATAAGCAAAAAGGAATCACTGACAGAAAAAATTCATTT
GACTTCAAAGCTTAAACAAGTGATTATCGCATCATCAGCACTGAGCTTACTAGTACTCCCTGTACTCATTTTCAATTTTT
ATATTTTCCAGCCCCTCTCTATTTTACTAACCATTGGCTTTGGGATGCTATTTGATTTGATACTCCTTCCGCTGTTACTT
ACAGTTTTTTTACTATCACTGACAGGATTAACGCTCAACCTAAACTGGATGTTTAAAACACTTGAAGCACTTGTTCAGCT
TGTAGACTGCCCTTTTCATTATCCACTTGTTTTGGGCAAGCCCAATGCAATACAACTCATACTTTTGTTGAGCATAACAG
CTCTGTTGCTCGATTTTTGGATGCAGAAAAAGCTGCGCTGGCTCCTATTATGCAGTCTGTTTATTATATTTTTCACCTGC
AAGAATCCAAGCCAGCCAACCATTACCGCAGTCGATGTCGGACAAGGAGATAGCATCTTTTTAAAGGATCGCTTTAATAA
ACAGACGATTTTGATTGATACAGGAGGAAGACTCAATATTCCAGAAAAAAGTTGGCAAAAAGCTCAAACAGAGTCAAATG
CATCTAAAACGCTCATCCCATATCTAGAATCCGAGGGAGTGAGTCAGATTGATCAGCTCATACTCACGCACACAGATGAC
GACCATGTCGGTGATTTTTTAAATCTTGCTGATAAAATAAAAATTAAAGAAGTATGGGTTAGTCCAGGAGAATTAACTTG
TCCAGACTTTGTAGGTAAATTAAAAAAAGCGAAAATTCCTATCCATCTCACTCAAGTTGGTGATGAAATTCCCATCTTTA
ACAGTCAACTTCAAGTTCTGTCCAACGGTTATACAGGAAAAGGGGACAACAATGATTCCATAGTGACCTATGGTAACTTT
TATGGGAAAAAGTTTTTATTCACAGGTGACTTAGAGCAAGATGGTGAAATGAAATTATTAAAAAACTATCCAAATTTAAA
AGTTGATATTTTAAAAGCAGGTCATCACGGGAGTAAAACGAGTTCAAATCCAAAGTTTATTAAACAAATTCAACCACAAT
TAGCGATCATATCAGTAGGAAAAAACAATCATTACGGACATCCCAATCAACAGACACTAGATACTTTCAAAAAATATAAA
GTAAAAAGTCTAAGAACAGATCAAAATGGTGCGATAAAACTCACTGAAATCAAAGGAATCTGGCGAATTTCGACAGTAAG
ATAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (206-461)

• Domain of unknown function (DUF4131) (DUF4131) (14-171)

• Metallo-beta-lactamase superfamily (Lactamase_B) (493-700)

3D structure

• AlphaFold DB: A0A387BIT3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Lactococcus lactis subsp. cremoris KW2	66.533	100	0.665
comEC/celB	Streptococcus pneumoniae TIGR4	46.184	100	0.47
comEC/celB	Streptococcus mitis NCTC 12261	45.982	100	0.467
comEC/celB	Streptococcus mitis SK321	46.286	100	0.467
comEC/celB	Streptococcus pneumoniae Rx1	45.395	100	0.462
comEC/celB	Streptococcus pneumoniae D39	45.395	100	0.462
comEC/celB	Streptococcus pneumoniae R6	45.395	100	0.462