Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   D7D53_RS05180 Genome accession   NZ_CP032621
Coordinates   1040271..1041008 (-) Length   245 a.a.
NCBI ID   WP_120770335.1    Uniprot ID   A0A387B3T0
Organism   Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1035271..1046008
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D7D53_RS05165 (D7D53_05165) msrB 1036925..1037863 (-) 939 WP_120770332.1 peptide-methionine (R)-S-oxide reductase MsrB -
  D7D53_RS05170 (D7D53_05170) thrB 1037962..1038831 (-) 870 WP_120770333.1 homoserine kinase -
  D7D53_RS05175 (D7D53_05175) - 1038833..1040119 (-) 1287 WP_120770334.1 homoserine dehydrogenase -
  D7D53_RS05180 (D7D53_05180) mecA 1040271..1041008 (-) 738 WP_120770335.1 adaptor protein MecA Regulator
  D7D53_RS05185 (D7D53_05185) - 1041216..1041520 (+) 305 Protein_999 helix-turn-helix domain-containing protein -
  D7D53_RS05190 (D7D53_05190) - 1041557..1042282 (+) 726 WP_120770856.1 hypothetical protein -
  D7D53_RS05195 (D7D53_05195) - 1042330..1045098 (-) 2769 WP_162927873.1 MBL fold metallo-hydrolase -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28452.26 Da        Isoelectric Point: 4.0199

>NTDB_id=317192 D7D53_RS05180 WP_120770335.1 1040271..1041008(-) (mecA) [Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)]
MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFEDLSDLPDMEELAQMSPDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQVEQEAESKKEPYIYYILSFA
KLADLVSFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDSDISRSVLQEYGQVLMNHDAVLN
LQKIG

Nucleotide


Download         Length: 738 bp        

>NTDB_id=317192 D7D53_RS05180 WP_120770335.1 1040271..1041008(-) (mecA) [Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)]
ATGAAAATGAAACAAATCAGTGATACAACTTTAAAAATCACGATGTCTTTAGAGGATTTGATGGATCGAGGAATGGAGAT
TGCTGACTTTCTCGTTCCTCAAGAAAAAACAGAAGAGTTCTTTTATGCTATCTTGGATGAGTTAGAGATGCCTGATAGCT
TTCTAGATACAGGTATGTTGAGCTTTCGTGTGACTCCAAAACCTGATAAGGTAGATGTCTTTGTAACCAAATCAAAGATT
GACCAAAATCTAGATTTTGAAGACTTATCGGATTTACCAGATATGGAAGAATTGGCTCAAATGTCGCCTGATGAATTTAT
CAAAACCTTGGAAAAAAGCATCGCAGACAAAACCAAGGATGATATTGAAGCCATTCAATCTCTAGAGCAAGTAGAAGCCA
AGGAAGAAGAGCAGGAGCAGGTTGAACAAGAAGCTGAAAGCAAGAAAGAGCCTTACATCTACTACATCCTTTCTTTTGCT
AAGTTGGCTGACTTGGTGTCTTTTGCCAAAACAGTGACTTTTGAGATGGAAACTTCTGAACTCTACAAGATGAACGAGCG
CTATTATTTGACCATTTTAGTAGATATTGAAAATCATCCAAGTCCATATCCAGCTTGGCTGTTGGCTCGTATGCGCGAGT
TTGCGGACGATAGTGACATCAGTCGCTCAGTCTTGCAAGAGTATGGCCAAGTCTTGATGAATCACGATGCAGTGCTTAAT
CTGCAAAAAATCGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A387B3T0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

98.367

100

0.984
  mecA Streptococcus pneumoniae D39

98.367

100

0.984
  mecA Streptococcus pneumoniae R6

98.367

100

0.984
  mecA Streptococcus pneumoniae TIGR4

97.959

100

0.98
  mecA Streptococcus mutans UA159

48.163

100

0.482
  mecA Streptococcus thermophilus LMD-9

46.586

100

0.473
  mecA Streptococcus thermophilus LMG 18311

46.185

100

0.469

Multiple sequence alignment