Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   D7D53_RS01050 Genome accession   NZ_CP032621
Coordinates   232234..234147 (+) Length   637 a.a.
NCBI ID   WP_120769856.1    Uniprot ID   A0A387AYM9
Organism   Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 227234..239147
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D7D53_RS01035 (D7D53_01035) fmt 229241..230176 (+) 936 WP_120769854.1 methionyl-tRNA formyltransferase -
  D7D53_RS01040 (D7D53_01040) rsmB 230169..231482 (+) 1314 WP_162927857.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  D7D53_RS01045 (D7D53_01045) - 231497..232237 (+) 741 WP_042751602.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  D7D53_RS01050 (D7D53_01050) stkP 232234..234147 (+) 1914 WP_120769856.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  D7D53_RS01055 (D7D53_01055) - 234236..234994 (+) 759 WP_120769857.1 threonine/serine exporter family protein -
  D7D53_RS01060 (D7D53_01060) - 234996..235445 (+) 450 WP_033682214.1 threonine/serine exporter family protein -
  D7D53_RS01065 (D7D53_01065) - 235559..236731 (+) 1173 WP_162927858.1 hydroxymethylglutaryl-CoA synthase -
  D7D53_RS01070 (D7D53_01070) - 236731..238005 (+) 1275 WP_120769859.1 hydroxymethylglutaryl-CoA reductase, degradative -

Sequence

Protein


Download         Length: 637 a.a.        Molecular weight: 69769.46 Da        Isoelectric Point: 9.4741

>NTDB_id=317174 D7D53_RS01050 WP_120769856.1 232234..234147(+) (stkP) [Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)]
MIQIGKIFAGRYRILKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEEGQQYLAMEYVAGLDLKRYIKEHHPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVVIKATAKKLTDRYKSVAEMYVDLSSSLSYNRRNEPKLVFDDATKADTKTLPKVPQSTLTSIPKAPVQEGRPQPK
PQTHQTEKTVPSPKPTKRRRMKARYPILLATFLLVVASLVWILYRTPATIAVPKVAGQTVAEAKEALKKANFEVGEEKTE
ASDKVEEGRVIRTDPDAGTGRKEGTKINLIVSSGQQSFQLGNYLGRKSSDVVAELKGKKVPENLIKIEEEESNEIEAGTI
MKQSLPEGTTYDLSKATQIVLTVAKKVNSISMPRYIGSTREFAVNNLTEIYGVKKANIEVVEVSTAPEGTAEETVVEQSP
KPGGKIDLASTRIKISIYKPKTPPSSSSSTSVQRGNQGSPTTPNQGNQQGGQQGNQQGTVPTPTQPNSEGNHENSRD

Nucleotide


Download         Length: 1914 bp        

>NTDB_id=317174 D7D53_RS01050 WP_120769856.1 232234..234147(+) (stkP) [Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)]
ATGATCCAAATCGGCAAGATTTTTGCCGGGCGGTATCGGATTCTCAAACAGATTGGTCGAGGAGGCATGGCAGATGTTTA
CTTGGCTAAAGATTTGATTCTAGACGGGGAAGAAGTGGCAGTTAAGGTCCTGAGGACCAACTACCAAACAGATCCTATTG
CAGTGGCTCGTTTTCAGCGGGAAGCGAGAGCCATGGCAGATCTGGACCATCCTCATATCGTTCGGATTACAGATATCGGT
GAAGAAGAGGGACAACAGTATCTCGCAATGGAATATGTTGCTGGATTAGACCTCAAACGCTATATCAAGGAACATCACCC
TCTTTCAAATGAAGAAGCGGTTCGAATCATGGGACAAATCCTCTTGGCTATGCGTTTAGCCCATACTCGAGGAATTGTTC
ACAGGGATTTGAAACCGCAAAATATCCTTTTGACCCCAGATGGGACTGCCAAAGTTACAGACTTTGGGATTGCGGTAGCC
TTTGCTGAGACAAGTCTGACCCAGACCAACTCAATGCTAGGTTCCGTTCATTATTTATCGCCAGAGCAGGCGCGTGGCTC
TAAAGCGACTGTACAGAGTGATATCTATGCCATGGGGATTATTTTCTATGAGATGTTGACTGGCCATATCCCTTACGATG
GGGATAGTGCAGTGACCATCGCCCTCCAGCATTTCCAGAAACCACTGCCATCGGTTATAGCTGAAAATCCATCTGTACCT
CAGGCTTTAGAAAATGTTGTTATCAAGGCAACTGCTAAGAAATTGACAGATCGCTACAAATCAGTCGCTGAGATGTATGT
GGACTTGTCGAGTAGTTTGTCTTATAATCGTCGTAATGAACCAAAGCTGGTCTTTGACGATGCGACTAAGGCGGATACCA
AGACTCTTCCTAAAGTTCCACAAAGTACCTTGACTTCTATTCCTAAAGCTCCGGTACAAGAGGGAAGACCTCAGCCTAAG
CCCCAAACTCATCAGACAGAAAAAACAGTACCTAGTCCAAAGCCAACTAAACGGCGTCGCATGAAAGCACGTTATCCAAT
TTTATTGGCGACCTTCTTGTTGGTTGTGGCATCCTTAGTATGGATTTTATATAGAACGCCTGCTACCATTGCCGTTCCAA
AGGTGGCAGGTCAGACGGTTGCTGAGGCTAAAGAAGCGCTTAAGAAAGCCAATTTTGAGGTTGGTGAAGAAAAAACAGAG
GCTAGTGATAAGGTTGAAGAAGGTCGTGTTATTCGTACCGATCCTGACGCTGGAACTGGTCGAAAAGAAGGAACAAAAAT
TAATTTGATTGTGTCTTCTGGTCAGCAATCCTTCCAACTTGGAAATTATCTTGGACGAAAATCTAGTGATGTAGTGGCAG
AATTGAAAGGCAAGAAGGTTCCAGAAAATCTAATTAAGATTGAGGAAGAAGAATCCAACGAAATCGAAGCCGGCACAATC
ATGAAACAAAGTTTACCGGAGGGAACAACCTACGATCTTAGCAAGGCAACTCAAATAGTTTTGACAGTTGCTAAAAAAGT
AAATTCGATTTCAATGCCAAGATATATTGGTTCAACTCGAGAATTTGCAGTTAATAATCTTACAGAGATATATGGAGTTA
AAAAAGCTAATATCGAAGTTGTAGAAGTGTCTACTGCTCCTGAAGGAACAGCTGAGGAGACTGTTGTAGAGCAAAGTCCA
AAACCGGGTGGAAAAATTGATTTAGCCAGCACACGTATTAAAATTTCGATTTATAAACCCAAAACACCACCATCAAGTTC
CTCTTCAACGTCAGTTCAACGTGGTAACCAAGGTTCACCTACTACTCCAAATCAAGGGAATCAACAAGGTGGTCAGCAAG
GAAATCAACAAGGAACGGTTCCTACTCCGACTCAACCAAATAGTGAAGGAAACCACGAAAATTCTCGTGATTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-227)

PASTA domain (PASTA)

(511-579)

PASTA domain (PASTA)

(371-432)

PASTA domain (PASTA)

(442-505)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A387AYM9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

78.803

91.837

0.724
  stkP Streptococcus pneumoniae D39

78.462

91.837

0.721
  stkP Streptococcus pneumoniae R6

78.462

91.837

0.721
  stkP Streptococcus pneumoniae Rx1

78.291

91.837

0.719
  pknB Streptococcus mutans UA159

55.786

90.895

0.507
  stkP/pknB Streptococcus salivarius strain HSISS4

54.054

92.936

0.502

Multiple sequence alignment