Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   D7D50_RS06195 Genome accession   NZ_CP032620
Coordinates   1228400..1229101 (+) Length   233 a.a.
NCBI ID   WP_117744500.1    Uniprot ID   -
Organism   Streptococcus koreensis strain KCOM 2890 (=JS71)     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1223400..1234101
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D7D50_RS06180 (D7D50_06180) - 1223956..1225278 (+) 1323 WP_120701746.1 glycosyltransferase family 4 protein -
  D7D50_RS06185 (D7D50_06185) thrS 1226085..1228028 (+) 1944 WP_120701747.1 threonine--tRNA ligase -
  D7D50_RS06195 (D7D50_06195) micA 1228400..1229101 (+) 702 WP_117744500.1 response regulator YycF Regulator
  D7D50_RS06200 (D7D50_06200) micB 1229094..1230440 (+) 1347 WP_117744499.1 cell wall metabolism sensor histidine kinase VicK Regulator
  D7D50_RS06205 (D7D50_06205) vicX 1230449..1231258 (+) 810 WP_048689535.1 MBL fold metallo-hydrolase Regulator
  D7D50_RS06210 (D7D50_06210) - 1231342..1231704 (+) 363 WP_023023915.1 YbaN family protein -
  D7D50_RS06215 (D7D50_06215) rnc 1231863..1232564 (+) 702 WP_117744497.1 ribonuclease III -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26654.62 Da        Isoelectric Point: 4.7260

>NTDB_id=317144 D7D50_RS06195 WP_117744500.1 1228400..1229101(+) (micA) [Streptococcus koreensis strain KCOM 2890 (=JS71)]
MKKILVVDDEKPISDIIKFNMAKEGYEVLTAFDGKEALAVFEAENPDILILDLMLPEIDGLEVARTIRKTSNVPIIVLSA
KDTEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRTELTVESQTESISDSDIVIGDLKIIPDAFLAQKKGKELELTH
REFELLYHLATHVGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDIPGRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=317144 D7D50_RS06195 WP_117744500.1 1228400..1229101(+) (micA) [Streptococcus koreensis strain KCOM 2890 (=JS71)]
ATGAAGAAAATTCTTGTTGTAGATGATGAAAAGCCGATTTCGGATATTATAAAATTCAATATGGCGAAAGAAGGTTATGA
AGTCTTGACTGCCTTCGATGGGAAAGAAGCACTGGCTGTTTTCGAAGCTGAGAACCCAGATATTTTGATTCTGGACCTCA
TGCTTCCTGAAATTGATGGTTTGGAAGTAGCGCGTACCATTCGAAAGACCAGTAATGTACCGATTATTGTCCTATCTGCT
AAAGATACCGAATTTGATAAGGTCATCGGTCTTGAAATTGGTGCGGATGACTATGTGACTAAGCCATTCTCCAATCGTGA
GCTTCAAGCTCGCGTAAAAGCTTTGTTGCGTCGGACAGAACTAACGGTAGAATCACAGACAGAGTCTATATCAGATTCAG
ATATTGTGATTGGTGATTTGAAAATCATTCCGGATGCCTTCCTTGCTCAGAAAAAAGGCAAAGAGCTCGAGCTGACCCAT
CGCGAATTTGAGTTGCTCTATCACTTGGCGACCCATGTAGGGCAAGTCATGACCCGTGAGCATTTACTGGAAACAGTCTG
GGGCTACGATTATTTTGGAGATGTTCGGACAGTGGACGTAACGATTCGACGTTTGCGTGAAAAAATCGAAGATATTCCAG
GTCGTCCGGAGTATATTTTAACGCGCCGCGGTGTCGGTTACTATATGAGAAACAATGATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

80.687

100

0.807
  vicR Streptococcus mutans UA159

77.966

100

0.79
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.589

99.142

0.442
  covR Streptococcus salivarius strain HSISS4

41.048

98.283

0.403

Multiple sequence alignment