Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   D7D50_RS01000 Genome accession   NZ_CP032620
Coordinates   181792..182538 (-) Length   248 a.a.
NCBI ID   WP_120701239.1    Uniprot ID   -
Organism   Streptococcus koreensis strain KCOM 2890 (=JS71)     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 176792..187538
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D7D50_RS00975 (D7D50_00975) sufU 176827..177261 (-) 435 WP_023022211.1 Fe-S cluster assembly sulfur transfer protein SufU -
  D7D50_RS00980 (D7D50_00980) - 177248..178474 (-) 1227 WP_120701236.1 cysteine desulfurase -
  D7D50_RS00985 (D7D50_00985) sufD 178477..179739 (-) 1263 WP_120701237.1 Fe-S cluster assembly protein SufD -
  D7D50_RS00990 (D7D50_00990) sufC 179781..180551 (-) 771 WP_117745248.1 Fe-S cluster assembly ATPase SufC -
  D7D50_RS00995 (D7D50_00995) - 180638..181795 (-) 1158 WP_120701238.1 glycosyltransferase family 4 protein -
  D7D50_RS01000 (D7D50_01000) mecA 181792..182538 (-) 747 WP_120701239.1 adaptor protein MecA Regulator
  D7D50_RS01005 (D7D50_01005) - 182704..183540 (-) 837 WP_120701240.1 undecaprenyl-diphosphate phosphatase -
  D7D50_RS01015 (D7D50_01015) - 183850..185757 (-) 1908 WP_120701241.1 DUF2207 domain-containing protein -
  D7D50_RS01020 (D7D50_01020) - 185876..187438 (+) 1563 WP_023022203.1 ABC transporter substrate-binding protein/permease -

Sequence

Protein


Download         Length: 248 a.a.        Molecular weight: 28844.49 Da        Isoelectric Point: 4.0873

>NTDB_id=317113 D7D50_RS01000 WP_120701239.1 181792..182538(-) (mecA) [Streptococcus koreensis strain KCOM 2890 (=JS71)]
MKMKQISDSTIKITIQLEDLEERGMEMADFLVPQEKTEEFFYTILDELEMPESFLDSGMLSFRVTPKPDKLDVFVTKSKI
DQHLNFEDFSDLPDMEELSQMSPDEFIKTLEKTISEKSKGDGDAIRHLEAEELADENQLSEEDTSNHPVDTRYIYYILQF
SQLEEVIRFTKTVHYAVETSELYKMDGMYYLTILIDLEGCPQDYPGWLLATMREYAEDTDTTRAVLQEHGHLLLVSDAIH
ELQKVNLV

Nucleotide


Download         Length: 747 bp        

>NTDB_id=317113 D7D50_RS01000 WP_120701239.1 181792..182538(-) (mecA) [Streptococcus koreensis strain KCOM 2890 (=JS71)]
ATGAAGATGAAGCAAATCAGTGATTCAACCATTAAAATCACGATTCAATTAGAGGATTTAGAAGAACGGGGCATGGAAAT
GGCCGATTTTTTGGTGCCTCAAGAAAAAACAGAAGAATTTTTCTATACCATCTTAGATGAATTAGAAATGCCAGAAAGTT
TCTTAGACAGTGGTATGTTAAGTTTTCGAGTGACCCCTAAGCCAGATAAACTCGATGTTTTTGTGACCAAATCAAAAATT
GATCAGCATTTAAATTTTGAAGATTTTTCCGATTTGCCTGATATGGAAGAATTGTCGCAAATGTCTCCGGACGAATTTAT
CAAAACCTTGGAAAAAACCATCTCTGAAAAGAGTAAGGGAGACGGCGATGCGATCCGTCATTTAGAAGCTGAGGAATTGG
CTGACGAAAATCAGCTTTCAGAAGAAGATACATCAAATCATCCAGTAGATACACGGTATATTTATTATATCCTCCAGTTT
TCTCAGTTAGAAGAAGTGATTCGGTTTACAAAAACAGTTCATTATGCTGTTGAGACTTCTGAACTTTATAAAATGGACGG
GATGTACTATTTAACCATCCTGATCGATTTGGAAGGGTGTCCGCAGGATTATCCAGGTTGGCTTTTGGCAACCATGCGTG
AATATGCGGAAGATACAGATACTACTAGAGCTGTCCTTCAGGAACATGGCCATCTCTTGCTCGTCTCAGATGCTATTCAC
GAACTTCAAAAGGTTAATTTGGTATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

66.26

99.194

0.657
  mecA Streptococcus pneumoniae D39

66.26

99.194

0.657
  mecA Streptococcus pneumoniae R6

66.26

99.194

0.657
  mecA Streptococcus pneumoniae TIGR4

66.26

99.194

0.657
  mecA Streptococcus mutans UA159

50.8

100

0.512
  mecA Streptococcus thermophilus LMD-9

46.185

100

0.464
  mecA Streptococcus thermophilus LMG 18311

45.783

100

0.46

Multiple sequence alignment