Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   D7D50_RS00515 Genome accession   NZ_CP032620
Coordinates   79983..81854 (-) Length   623 a.a.
NCBI ID   WP_120701190.1    Uniprot ID   -
Organism   Streptococcus koreensis strain KCOM 2890 (=JS71)     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 74983..86854
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D7D50_RS00490 (D7D50_00490) - 75715..76083 (-) 369 WP_120701187.1 S1 RNA-binding domain-containing protein -
  D7D50_RS00495 (D7D50_00495) - 76080..77486 (-) 1407 WP_120701188.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  D7D50_RS00500 (D7D50_00500) - 77531..78163 (-) 633 WP_023022361.1 response regulator transcription factor -
  D7D50_RS00505 (D7D50_00505) - 78141..79160 (-) 1020 WP_120701189.1 sensor histidine kinase -
  D7D50_RS00510 (D7D50_00510) liaF 79157..79852 (-) 696 WP_117745175.1 cell wall-active antibiotics response protein LiaF -
  D7D50_RS00515 (D7D50_00515) stkP 79983..81854 (-) 1872 WP_120701190.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  D7D50_RS00520 (D7D50_00520) - 81851..82591 (-) 741 WP_023022352.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  D7D50_RS00525 (D7D50_00525) rsmB 82613..83926 (-) 1314 WP_023022350.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  D7D50_RS00530 (D7D50_00530) fmt 83916..84851 (-) 936 WP_117745178.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 623 a.a.        Molecular weight: 68447.59 Da        Isoelectric Point: 5.2801

>NTDB_id=317104 D7D50_RS00515 WP_120701190.1 79983..81854(-) (stkP) [Streptococcus koreensis strain KCOM 2890 (=JS71)]
MIQIGKIFAGRYKIIRQIGRGGMADVYLARDLILDGEEVAVKVLRTNYQTDPIAVARFQREAKAMADLDHPNIVRITDIG
EEEGQQYLAMEYVAGLDLKRYIKENAPLSNEEAVRLMGQILLAMRLAHTQGIIHRDLKPQNVLLTPDGNAKVSDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKASVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSIIEENKNVP
QALENVVIKATAKKLSDRYKSVAEMYVDLSSCLSYERRNEKKLVFDDASKADTKTLPKVNVVPKPTPLPTSDVRPVVHED
LPGASEDRTVPVSPKNKPRRRLRTRYKVLFVALALVLAAFAFLLYMSPANKTVPDVSGKTVAEARAIIEDQDLQVGDEKE
EYSDSVLEGYVIRTNPNAGAQKKENSKVDLVVSKGPSTFDMPDYTGMSRENAENDLKTNYKLSSKLISIEEVETNEVEPG
IVIEQSPVAGQKYDLTSNTKVVLKVSKESNSIDLPSYVGSDYEFAVSNLVEIYGVKEANIERKTTSHLPAGVEVLPGQIV
SQTPEAQSSIDIKKTRIVLTVYEPKTEPSSSTKASSSSSEGSTSTTVESHSNTESSATTEPEP

Nucleotide


Download         Length: 1872 bp        

>NTDB_id=317104 D7D50_RS00515 WP_120701190.1 79983..81854(-) (stkP) [Streptococcus koreensis strain KCOM 2890 (=JS71)]
ATGATTCAAATCGGCAAAATTTTTGCCGGACGATATAAGATAATCCGCCAAATCGGGCGTGGAGGGATGGCAGATGTCTA
TCTCGCTCGGGATTTAATCTTAGATGGTGAAGAAGTTGCAGTTAAAGTACTGAGGACCAATTACCAAACAGATCCAATTG
CAGTTGCTCGCTTCCAACGAGAGGCTAAAGCGATGGCAGATTTGGATCATCCAAATATCGTTCGGATCACGGATATCGGT
GAAGAGGAAGGCCAACAATACTTGGCGATGGAATATGTCGCTGGCTTAGACTTGAAACGTTATATCAAGGAAAATGCTCC
TCTTTCAAATGAAGAAGCCGTTCGCTTGATGGGGCAAATTCTTCTTGCTATGCGCTTGGCGCACACGCAAGGGATTATTC
ACCGTGACTTAAAGCCTCAAAACGTTCTTTTAACACCAGATGGAAATGCCAAGGTCTCTGACTTTGGGATTGCGGTAGCC
TTTGCAGAAACGAGTCTCACTCAGACAAACTCTATGTTGGGATCGGTTCATTATTTGTCTCCTGAACAAGCTAGAGGATC
GAAAGCTTCTGTTCAAAGCGATATTTATGCAATGGGGATTATATTCTACGAAATGCTGACGGGACATATCCCTTATGATG
GGGATAGTGCAGTGACGATCGCGCTACAACATTTCCAAAAACCACTTCCGTCCATCATCGAAGAGAATAAAAATGTTCCA
CAGGCCTTGGAAAATGTGGTTATTAAAGCAACAGCAAAGAAACTATCCGATCGCTATAAGTCGGTAGCTGAAATGTATGT
TGACCTCTCTAGTTGCTTATCTTATGAGCGTCGTAACGAGAAAAAATTGGTCTTTGATGATGCTTCAAAAGCAGATACCA
AAACCCTACCAAAGGTAAACGTGGTTCCAAAACCAACGCCACTTCCAACATCAGATGTTCGTCCGGTTGTTCATGAGGAC
CTACCAGGGGCTTCAGAGGATAGAACGGTTCCAGTTTCTCCAAAAAATAAGCCACGTCGTCGTTTGAGGACACGCTACAA
AGTCTTGTTTGTTGCTTTAGCTTTGGTACTAGCTGCCTTTGCCTTTCTTCTTTATATGAGTCCAGCCAACAAAACAGTTC
CGGATGTATCTGGAAAAACTGTTGCAGAAGCTCGTGCTATCATTGAAGATCAGGATCTTCAAGTTGGAGACGAAAAAGAA
GAATACAGTGATTCTGTACTTGAAGGCTATGTGATTCGTACCAATCCAAATGCAGGAGCTCAGAAAAAAGAAAACAGCAA
GGTTGATTTGGTTGTCTCGAAAGGACCAAGCACCTTTGATATGCCAGACTATACTGGTATGTCTAGAGAAAATGCAGAAA
ATGATCTGAAAACCAACTATAAGCTTTCTAGCAAACTCATTTCGATTGAAGAAGTCGAGACCAATGAAGTAGAACCAGGA
ATCGTTATTGAGCAATCTCCTGTCGCTGGTCAAAAATATGATTTGACTTCTAATACGAAGGTTGTTCTGAAAGTATCTAA
GGAAAGTAATTCTATCGATTTACCAAGTTATGTCGGTTCTGATTATGAGTTTGCTGTCTCTAATCTCGTTGAAATCTACG
GGGTGAAGGAAGCAAATATTGAACGGAAGACCACATCGCATCTTCCAGCTGGAGTAGAAGTCTTACCAGGTCAAATTGTG
AGTCAGACTCCGGAAGCTCAATCAAGCATCGATATTAAGAAGACTCGCATTGTCTTGACCGTGTACGAACCGAAGACGGA
ACCATCAAGTAGTACGAAAGCTTCAAGCAGTTCATCAGAAGGTTCAACCTCTACAACAGTGGAATCACATTCCAATACGG
AATCCTCAGCTACCACTGAACCAGAACCTTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-255)

PASTA domain (PASTA)

(440-507)

PASTA domain (PASTA)

(372-434)

PASTA domain (PASTA)

(514-582)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

63.032

94.222

0.594
  stkP Streptococcus pneumoniae D39

62.862

94.222

0.592
  stkP Streptococcus pneumoniae R6

62.862

94.222

0.592
  stkP Streptococcus pneumoniae Rx1

62.692

94.222

0.591
  pknB Streptococcus mutans UA159

58.118

86.998

0.506
  stkP/pknB Streptococcus salivarius strain HSISS4

51.057

98.716

0.504

Multiple sequence alignment