Detailed information NTG0316923

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: PA34_RS26760
• Genome accession: NZ_CP032552
• Coordinates: 5553664..5555001 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain PA34
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5548664..5560001

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PA34_RS26735 (PA34_026735)	pgeF	5548807..5549535 (-)	729	WP_003094684.1	peptidoglycan editing factor PgeF	-
PA34_RS26740 (PA34_026740)	rluD	5549532..5550494 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
PA34_RS26745 (PA34_026745)	-	5550640..5551665 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
PA34_RS26750 (PA34_026750)	-	5551822..5552067 (+)	246	WP_003102591.1	PP0621 family protein	-
PA34_RS26755 (PA34_026755)	pilS	5552057..5553649 (+)	1593	WP_033989041.1	two-component system sensor histidine kinase PilS	Regulator
PA34_RS26760 (PA34_026760)	pilR	5553664..5555001 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
PA34_RS26765 (PA34_026765)	thiO	5555047..5556141 (-)	1095	WP_003141551.1	glycine oxidase ThiO	-
PA34_RS26770 (PA34_026770)	-	5556281..5556781 (+)	501	WP_016562346.1	GspH/FimT family pseudopilin	-
PA34_RS26775 (PA34_026775)	-	5556904..5557392 (+)	489	WP_003141552.1	GspH/FimT family pseudopilin	-
PA34_RS26780 (PA34_026780)	pilV	5557402..5557926 (+)	525	WP_003116261.1	type IV pilus modification protein PilV	Machinery gene
PA34_RS26785 (PA34_026785)	-	5557935..5558750 (+)	816	WP_016254061.1	prepilin-type N-terminal cleavage/methylation domain-containing protein	-
PA34_RS26790 (PA34_026790)	-	5558747..5559352 (+)	606	WP_003116263.1	pilus assembly protein	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=316923 PA34_RS26760 WP_003094694.1 5553664..5555001(+) (pilR) [Pseudomonas aeruginosa strain PA34]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=316923 PA34_RS26760 WP_003094694.1 5553664..5555001(+) (pilR) [Pseudomonas aeruginosa strain PA34]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGCAGCGGCAAGGAACTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCACCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTATACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATCGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCACTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384