Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   E5491_RS10350 Genome accession   NZ_CP039156
Coordinates   2016277..2016900 (-) Length   207 a.a.
NCBI ID   WP_001045135.1    Uniprot ID   -
Organism   Staphylococcus aureus strain WCUH29     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2011277..2021900
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E5491_RS10320 (E5491_10375) - 2011617..2012813 (-) 1197 WP_000238227.1 exonuclease SbcCD subunit D -
  E5491_RS10325 (E5491_10380) - 2013104..2013202 (-) 99 WP_001802255.1 hypothetical protein -
  E5491_RS10335 (E5491_10390) - 2013741..2014085 (-) 345 WP_000290301.1 YlbF/YmcA family competence regulator -
  E5491_RS10340 (E5491_10395) - 2014154..2015278 (-) 1125 WP_000992518.1 DUF445 domain-containing protein -
  E5491_RS10345 (E5491_10400) - 2015457..2015921 (-) 465 WP_000375864.1 helix-turn-helix transcriptional regulator -
  E5491_RS10350 (E5491_10405) vraR 2016277..2016900 (-) 624 WP_001045135.1 response regulator transcription factor Regulator
  E5491_RS10355 (E5491_10410) - 2016922..2018034 (-) 1113 WP_000437969.1 GAF domain-containing sensor histidine kinase -
  E5491_RS10360 (E5491_10415) - 2018197..2019018 (+) 822 WP_000669376.1 RluA family pseudouridine synthase -
  E5491_RS10365 (E5491_10420) fumC 2019471..2020856 (-) 1386 WP_000116228.1 class II fumarate hydratase -
  E5491_RS10370 (E5491_10425) - 2021052..2021447 (-) 396 WP_000901023.1 hypothetical protein -

Sequence

Protein


Download         Length: 207 a.a.        Molecular weight: 23909.59 Da        Isoelectric Point: 5.5759

>NTDB_id=316922 E5491_RS10350 WP_001045135.1 2016277..2016900(-) (vraR) [Staphylococcus aureus strain WCUH29]
MNKVILVDDHYIVRQGLRFLLSTIENIEVLQDFADGETFLEYLKEHEHPDIVLLDLVMPGMNGIEITEYIKAHYPEIKVL
VLTSYVDDEHVISAINKGADGYEMKDVEPQQLIETIRRVMNGEKMIHPKAQDVFETVSQKPHYTNKLSKREIEVLREMVK
GKTNKEIAETLFVSEKTIKTHVSHIFSKLQVSDRTQAAIYAMENKLI

Nucleotide


Download         Length: 624 bp        

>NTDB_id=316922 E5491_RS10350 WP_001045135.1 2016277..2016900(-) (vraR) [Staphylococcus aureus strain WCUH29]
ATGAACAAAGTAATATTAGTAGATGACCATTATATTGTGCGACAAGGATTGCGATTTTTATTATCCACGATTGAAAACAT
AGAAGTTTTACAAGACTTTGCAGATGGAGAAACATTTTTAGAATATTTAAAAGAGCATGAGCACCCTGATATTGTGCTAT
TAGATTTAGTGATGCCTGGCATGAATGGTATTGAAATTACGGAATATATTAAGGCACATTATCCGGAAATTAAAGTTTTG
GTATTAACAAGTTATGTTGATGATGAACATGTAATTTCAGCAATCAATAAAGGTGCTGATGGTTATGAAATGAAAGACGT
TGAGCCTCAGCAATTAATTGAAACTATTAGACGAGTTATGAACGGTGAAAAAATGATACATCCTAAGGCACAAGATGTAT
TCGAAACAGTTAGCCAAAAACCACACTACACGAATAAGTTGTCAAAGAGAGAAATTGAAGTGTTACGTGAAATGGTTAAA
GGTAAAACAAATAAAGAGATTGCAGAAACTTTATTTGTATCTGAAAAAACAATTAAAACACATGTCAGTCATATATTTAG
TAAATTACAAGTTAGCGATCGTACACAAGCAGCAATTTATGCAATGGAAAATAAGTTGATTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(146-201)

Response regulator receiver domain (Response_reg)

(4-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.58

100

0.406
  degU Bacillus subtilis subsp. subtilis str. 168

35.586

100

0.382
  letA Legionella pneumophila str. Paris

35.714

100

0.362
  letA Legionella pneumophila strain ERS1305867

35.714

100

0.362

Multiple sequence alignment