Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   LLW34_RS11945 Genome accession   NZ_CP032430
Coordinates   2287693..2288916 (+) Length   407 a.a.
NCBI ID   WP_021211225.1    Uniprot ID   A0A896TDA0
Organism   Lactococcus cremoris strain W34     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2282693..2293916
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLW34_RS11920 (LLW34_2328) - 2283807..2284610 (-) 804 WP_205288153.1 phosphatidate cytidylyltransferase -
  LLW34_RS11925 (LLW34_2329) - 2284610..2285344 (-) 735 WP_205288154.1 isoprenyl transferase -
  LLW34_RS11930 (LLW34_2330) yajC 2285694..2286026 (-) 333 WP_011677192.1 preprotein translocase subunit YajC -
  LLW34_RS11935 (LLW34_2331) - 2286121..2286813 (-) 693 Protein_2324 DNA alkylation repair protein -
  LLW34_RS11940 (LLW34_2332) rlmH 2286838..2287317 (-) 480 WP_011677194.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  LLW34_RS11945 (LLW34_2333) htrA 2287693..2288916 (+) 1224 WP_021211225.1 S1C family serine protease Regulator
  LLW34_RS11950 (LLW34_2334) - 2289038..2290036 (+) 999 WP_014573349.1 glycosyltransferase family 4 protein -
  LLW34_RS11955 (LLW34_2335) - 2290174..2291514 (+) 1341 WP_021211227.1 glycosyltransferase family 4 protein -
  LLW34_RS11960 (LLW34_2336) - 2291622..2291846 (+) 225 WP_011677198.1 YkuJ family protein -
  LLW34_RS11965 (LLW34_2337) - 2291990..2292994 (+) 1005 WP_205288155.1 hypothetical protein -
  LLW34_RS11970 (LLW34_2338) - 2293051..2293803 (-) 753 WP_021211229.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 41496.98 Da        Isoelectric Point: 5.7726

>NTDB_id=315840 LLW34_RS11945 WP_021211225.1 2287693..2288916(+) (htrA) [Lactococcus cremoris strain W34]
MAKANIGKLLLTGVVGGAIALGGSAIYQSTTNQLGNANRSNTTSTKVSNVSVNVNTDVTSAIKKVSNSVVSVMNYQKQNS
QSDFSSIFGGNSGSSSANDGLQLSSEGSGVIYKKSGGDAYVVTNYHVIAGNSSLDVLLSGGQKVKATVVGYDEYTDLAVL
KISSDHVKDVATFADSSKLTIGEPAIAVGSPLGSQFANTATEGILSATSRQVTLTQENGQTTSINAIQTDAAINPGNSGG
ALINIEGQVIGITQSKITTTEDGSTSVEGLGFAIPSNDVVNIINKLETDGKISRPALGIRMVDLSQLSTNDSSQLKLPSS
VTGGVVVYSVQAGLPAATAGLKAGDVITKVGDTAVTSSTDLQSALYSHNINDTVKVTYYRDGKSATANVKLSKSTSALET
NSSSSSN

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=315840 LLW34_RS11945 WP_021211225.1 2287693..2288916(+) (htrA) [Lactococcus cremoris strain W34]
ATGGCAAAAGCTAATATAGGAAAATTGCTATTAACCGGTGTTGTGGGTGGAGCTATCGCACTCGGAGGAAGCGCAATTTA
TCAAAGCACTACAAACCAACTAGGAAATGCTAACCGCTCAAATACAACTAGCACAAAGGTTAGTAATGTTTCGGTAAATG
TCAATACCGATGTCACCTCTGCAATTAAAAAAGTTTCAAATTCTGTCGTTTCTGTTATGAATTATCAAAAACAGAATTCA
CAAAGTGATTTTAGTTCAATTTTTGGTGGAAATAGCGGCTCAAGTTCAGCTAATGACGGCTTGCAACTTTCCAGTGAGGG
TTCTGGTGTTATTTATAAAAAATCTGGTGGAGATGCTTACGTGGTCACTAACTATCACGTTATTGCTGGAAATAGTTCCC
TCGATGTTTTACTTTCTGGTGGGCAAAAAGTTAAAGCCACAGTTGTTGGTTATGATGAATACACTGACCTTGCCGTTCTT
AAAATCAGCTCTGACCATGTTAAAGACGTGGCAACTTTCGCTGATTCAAGCAAGTTAACTATTGGTGAACCAGCTATTGC
AGTCGGCTCACCTTTAGGTAGCCAGTTTGCTAATACTGCAACCGAAGGAATTCTGTCTGCAACAAGTCGTCAAGTCACTT
TGACTCAAGAAAATGGTCAAACAACAAGTATCAATGCGATTCAAACGGATGCTGCCATTAACCCGGGTAACTCAGGTGGA
GCCTTGATTAATATTGAAGGTCAAGTGATTGGTATTACTCAAAGTAAAATCACAACGACCGAAGATGGTTCTACCTCTGT
GGAAGGTTTAGGTTTTGCTATCCCATCTAATGATGTGGTAAACATCATTAATAAACTTGAAACTGATGGTAAGATTTCAC
GTCCTGCCTTAGGTATTCGTATGGTTGACCTATCTCAATTATCAACAAATGATAGTTCTCAACTGAAATTACCTAGCAGC
GTAACTGGTGGAGTGGTTGTCTACTCTGTTCAAGCGGGTCTTCCTGCTGCCACAGCTGGTCTGAAAGCTGGCGATGTGAT
AACGAAGGTGGGAGATACCGCCGTTACTTCATCAACAGACTTACAAAGTGCTCTTTACTCACACAATATTAATGATACTG
TGAAAGTCACCTACTACCGTGATGGTAAATCAGCCACAGCAAATGTTAAACTCTCTAAATCAACAAGCGCTTTAGAAACA
AATAGTTCATCTTCTTCTAATTAA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(237-395)

Trypsin-like peptidase domain (Trypsin_2)

(107-252)

PDZ domain (PDZ_2)

(295-391)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

54.872

95.823

0.526
  htrA Streptococcus mitis NCTC 12261

55.614

94.103

0.523
  htrA Streptococcus pneumoniae Rx1

57.849

84.521

0.489
  htrA Streptococcus pneumoniae D39

57.849

84.521

0.489
  htrA Streptococcus pneumoniae R6

57.849

84.521

0.489
  htrA Streptococcus pneumoniae TIGR4

57.849

84.521

0.489
  htrA Streptococcus mutans UA159

53.117

90.663

0.482

Multiple sequence alignment