Detailed information NTG0315503

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: D5R92_RS05500
• Genome accession: NZ_CP032401
• Coordinates: 1149353..1150555 (+)
• Length: 400 a.a.
• NCBI ID: WP_016356270.1
• Uniprot ID: -
• Organism: Streptococcus iniae strain GX005
• Function: require for competence development (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	1148026..1149201	1149353..1150555	flank	152

Gene organization within MGE regions

Location: 1148026..1150555

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D5R92_RS05495 (D5R92_05495)	-	1148026..1149201 (+)	1176	WP_003099060.1	IS256 family transposase	-
D5R92_RS05500 (D5R92_05500)	htrA	1149353..1150555 (+)	1203	WP_016356270.1	S1C family serine protease	Regulator

Sequence

Protein

• Length: 400 a.a.
• Molecular weight: 42479.20 Da
• Isoelectric Point: 6.7483

>NTDB_id=315503 D5R92_RS05500 WP_016356270.1 1149353..1150555(+) (htrA) [Streptococcus iniae strain GX005]
MSHFKNIYKLIWVLLAGFLGGFFAFIVINTFNQKTSTQETIISNPTKTSKVTYKNTTNTTKAVKVIQNAVVSVLNYQAVD
TNTSNPASQLFGQENDLKKDDGLSLFSEGSGVIYKKDDKSAYLVTNNHVIDGAKRIEILLADGSKVVGKLVGSDTYSDLA
VVKISADKIKSIGEFADSTKINVGEVAIAIGSPLGSEYANSVTEGIVSSLSRTVTLKNEEGQTVSTNALQTDAAINPGNS
GGPLINIEGQIIGINSSKISSGSNGGAVEGMGFAIPSNDVLKIINQLEGKGEVIRPALGISMVNLGDLSTNAISQLKIPK
DLTGGIVVASVKEGMPASGKLEQYDIITEINGKAVTTTSDLQSELYGHNIDDSIKITFYRGKDKKTDTIKLTKTTKDLEK

Nucleotide

• Length: 1203 bp

>NTDB_id=315503 D5R92_RS05500 WP_016356270.1 1149353..1150555(+) (htrA) [Streptococcus iniae strain GX005]
ATGTCACATTTTAAAAATATATACAAATTAATTTGGGTTCTTTTGGCAGGCTTTTTAGGTGGTTTTTTTGCATTTATAGT
TATTAATACCTTTAATCAAAAAACTTCTACACAAGAGACAATTATTTCAAATCCTACTAAAACAAGTAAAGTAACTTATA
AAAACACAACTAATACAACTAAAGCGGTAAAGGTTATCCAAAATGCTGTTGTATCTGTGCTCAATTATCAAGCAGTTGAT
ACAAATACGTCAAATCCTGCAAGTCAACTTTTTGGACAAGAAAATGATTTAAAAAAAGATGACGGGCTATCTCTTTTTAG
TGAAGGATCTGGTGTCATTTATAAAAAAGATGATAAATCTGCTTATTTAGTAACAAATAATCATGTTATTGATGGTGCTA
AACGAATTGAAATTCTACTAGCTGATGGTTCTAAAGTTGTTGGAAAATTAGTTGGTTCTGATACTTATTCAGATTTAGCT
GTTGTTAAAATTTCAGCTGATAAAATTAAATCTATTGGAGAATTTGCTGACTCTACAAAAATAAATGTTGGTGAAGTTGC
AATTGCTATTGGTAGCCCACTGGGATCTGAATATGCTAATTCCGTAACAGAAGGTATTGTTTCAAGTCTTAGCAGAACAG
TTACTCTAAAAAATGAAGAAGGACAGACCGTTTCAACAAATGCTCTACAAACAGATGCAGCAATTAATCCTGGTAATTCA
GGTGGTCCATTAATCAATATTGAAGGGCAAATTATTGGGATTAATTCAAGTAAAATTTCTTCAGGTTCAAATGGAGGAGC
TGTCGAAGGAATGGGATTTGCAATTCCTTCCAATGACGTTCTTAAAATTATTAATCAACTTGAAGGAAAAGGAGAAGTGA
TTCGTCCTGCCTTAGGCATTTCAATGGTTAATCTTGGTGATCTGTCAACAAATGCAATTAGCCAATTAAAGATTCCAAAG
GACTTAACAGGTGGTATTGTTGTCGCATCTGTCAAAGAAGGGATGCCTGCTTCAGGAAAACTTGAGCAATACGATATTAT
TACAGAAATTAATGGCAAAGCTGTCACTACAACAAGTGATCTTCAAAGTGAATTATATGGACATAATATTGACGACTCAA
TCAAAATAACTTTCTATAGAGGAAAAGATAAGAAAACAGATACCATCAAACTAACAAAGACAACTAAAGATTTAGAAAAA
TAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (109-254)

• Peptidase family M50 (Peptidase_M50) (11-396)

• PDZ domain (PDZ_2) (296-391)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	62.025	98.75	0.612
htrA	Streptococcus mitis NCTC 12261	54.208	100	0.548
htrA	Streptococcus pneumoniae Rx1	53.96	100	0.545
htrA	Streptococcus pneumoniae D39	53.96	100	0.545
htrA	Streptococcus pneumoniae R6	53.96	100	0.545
htrA	Streptococcus pneumoniae TIGR4	53.96	100	0.545
htrA	Streptococcus gordonii str. Challis substr. CH1	54.386	99.75	0.543