Detailed information NTG0315472

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: D5R92_RS00090
• Genome accession: NZ_CP032401
• Coordinates: 17470..18315 (+)
• Length: 281 a.a.
• NCBI ID: WP_003099573.1
• Uniprot ID: A0A1J0MYY1
• Organism: Streptococcus iniae strain GX005
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 12470..23315

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D5R92_RS00065 (D5R92_00065)	-	12592..13914 (+)	1323	WP_225111305.1	PTS sugar transporter subunit IIC	-
D5R92_RS00070 (D5R92_00070)	-	13911..14750 (+)	840	WP_003099563.1	alpha/beta hydrolase	-
D5R92_RS00075 (D5R92_00075)	ylqF	15220..16074 (+)	855	WP_003099566.1	ribosome biogenesis GTPase YlqF	-
D5R92_RS00080 (D5R92_00080)	-	16058..16843 (+)	786	WP_003099568.1	ribonuclease HII	-
D5R92_RS00085 (D5R92_00085)	-	16856..17404 (+)	549	WP_003099570.1	sugar O-acetyltransferase	-
D5R92_RS00090 (D5R92_00090)	dprA	17470..18315 (+)	846	WP_003099573.1	DNA-processing protein DprA	Machinery gene
D5R92_RS00095 (D5R92_00095)	topA	18412..20547 (+)	2136	WP_003099575.1	type I DNA topoisomerase	-
D5R92_RS00100 (D5R92_00100)	-	20641..21525 (-)	885	WP_003099578.1	LysR family transcriptional regulator	-
D5R92_RS00105 (D5R92_00105)	-	21691..22749 (+)	1059	WP_003099589.1	PTS transporter subunit IIC	-

Sequence

Protein

• Length: 281 a.a.
• Molecular weight: 31550.74 Da
• Isoelectric Point: 9.9826

>NTDB_id=315472 D5R92_RS00090 WP_003099573.1 17470..18315(+) (dprA) [Streptococcus iniae strain GX005]
MNNFELYKLKKAGLKNHHILNIIHYSQQTKKSLSLRNMAVVSGTSKPCLFLENYKLLNIKELRVEFKKYPSFSILDKTYP
LALKEIDNPPVLLFYQGNLELLNRHKLAVVGSRKSSAVGNKSVESLIKQLNNQFVIVSGLARGIDTVAHFSSIKQGGETI
AVIGSGLDIYYPKENRRLQEFIAEKHLLLSEYCPKEAPLAHHFPERNRIIAGLSMGVLVAEAKWRSGSLITCRFALDYGR
DIFVVPGAILDKQSQGGNHLIQEGAKLVTKGLDIISEYQFL

Nucleotide

• Length: 846 bp

>NTDB_id=315472 D5R92_RS00090 WP_003099573.1 17470..18315(+) (dprA) [Streptococcus iniae strain GX005]
ATGAATAACTTTGAACTGTATAAATTAAAGAAAGCTGGCCTAAAAAATCATCATATTCTAAATATCATTCATTATAGCCA
GCAAACTAAGAAATCTCTATCACTTAGAAATATGGCTGTTGTTTCAGGAACAAGTAAACCATGTCTGTTTTTAGAAAATT
ACAAGCTGTTAAATATAAAAGAGTTACGAGTAGAATTTAAGAAGTATCCCAGCTTTTCAATTTTAGACAAGACCTATCCC
CTTGCTTTAAAAGAAATTGATAATCCGCCAGTATTATTATTTTATCAAGGAAATTTAGAGCTTTTAAATCGGCATAAATT
AGCAGTGGTAGGGTCAAGGAAATCCTCAGCAGTTGGAAACAAATCTGTTGAATCTCTCATCAAGCAACTTAATAATCAGT
TTGTTATTGTTAGTGGGTTGGCTAGAGGAATTGATACTGTAGCTCATTTTTCGAGCATCAAACAAGGTGGAGAGACTATT
GCTGTTATTGGATCAGGGTTAGACATTTATTATCCTAAGGAAAATAGAAGATTACAGGAGTTTATTGCTGAAAAGCATTT
ATTATTAAGTGAATATTGCCCTAAGGAAGCACCTTTAGCACATCATTTTCCAGAACGAAATCGCATAATTGCAGGCTTAT
CTATGGGAGTTTTAGTGGCAGAAGCCAAATGGCGTTCTGGTAGTCTAATCACTTGTCGCTTTGCACTTGATTACGGTAGG
GATATTTTTGTTGTTCCAGGCGCCATCCTTGACAAACAGTCGCAGGGAGGGAATCACCTCATTCAAGAGGGAGCGAAGCT
TGTTACAAAAGGACTTGACATCATTTCTGAATACCAATTTTTATAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (73-269)

3D structure

• AlphaFold DB: A0A1J0MYY1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	66.786	99.644	0.665
dprA/cilB/dalA	Streptococcus mitis SK321	57.5	99.644	0.573
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	57.143	99.644	0.569
dprA/cilB/dalA	Streptococcus pneumoniae D39	57.143	99.644	0.569
dprA/cilB/dalA	Streptococcus pneumoniae R6	57.143	99.644	0.569
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	57.143	99.644	0.569
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	56.786	99.644	0.566
dprA	Lactococcus lactis subsp. cremoris KW2	54.643	99.644	0.544