Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   D5R90_RS07745 Genome accession   NZ_CP032400
Coordinates   1568854..1569615 (+) Length   253 a.a.
NCBI ID   WP_003100848.1    Uniprot ID   A0A3L8GPI6
Organism   Streptococcus iniae strain YM011     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1563854..1574615
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D5R90_RS07725 (D5R90_07725) - 1564797..1564913 (-) 117 WP_016355825.1 putative metal homeostasis protein -
  D5R90_RS07730 (D5R90_07730) - 1565111..1565851 (-) 741 WP_003100842.1 amino acid ABC transporter ATP-binding protein -
  D5R90_RS07735 (D5R90_07735) - 1565844..1567412 (-) 1569 WP_003100845.1 ABC transporter substrate-binding protein/permease -
  D5R90_RS07740 (D5R90_07740) - 1567895..1568734 (+) 840 WP_003100846.1 undecaprenyl-diphosphate phosphatase -
  D5R90_RS07745 (D5R90_07745) mecA 1568854..1569615 (+) 762 WP_003100848.1 adaptor protein MecA Regulator
  D5R90_RS07750 (D5R90_07750) - 1569618..1570778 (+) 1161 WP_016355826.1 glycosyltransferase family 4 protein -
  D5R90_RS07755 (D5R90_07755) sufC 1570902..1571672 (+) 771 WP_003100850.1 Fe-S cluster assembly ATPase SufC -
  D5R90_RS07760 (D5R90_07760) sufD 1571743..1573005 (+) 1263 WP_003100851.1 Fe-S cluster assembly protein SufD -
  D5R90_RS07765 (D5R90_07765) - 1573024..1574250 (+) 1227 WP_003100852.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29300.80 Da        Isoelectric Point: 4.0647

>NTDB_id=315460 D5R90_RS07745 WP_003100848.1 1568854..1569615(+) (mecA) [Streptococcus iniae strain YM011]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYAVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSDI
NKDLNFEDLSDLGDISQMSPEDFFKSIEKAMMEKGDVNAHEKLEKIEEMMEEAINTSQENAEPTQTQVESEPQVLDYVHY
VLDFDNITEAVTFAKTLDFSIEASELYKDGGRYHMTILLDVQNQPSYYANIMYARLIEHASAGTRTRAYLQEHASQLIDD
NAIEQLQRIELVD

Nucleotide


Download         Length: 762 bp        

>NTDB_id=315460 D5R90_RS07745 WP_003100848.1 1568854..1569615(+) (mecA) [Streptococcus iniae strain YM011]
ATGGAGATGAAACAGATTAGCGAAACGACGCTAAAAATAACAATCAGCATGGATGATTTAGAAGAAAGAGGAATGGAGCT
TAAAGATTTTTTAATTCCTCAAGAAAAAACAGAAGAGTTTTTCTATGCGGTTATGGATGAGTTAGATTTACCAGATAATT
TTAAAGATAGTGGTATGTTAAGTTTTCGAGTGACACCACGTAAAGACAGACTAGATGTGTTTGTTACTAAATCTGATATT
AATAAAGACCTTAACTTTGAAGACTTATCTGATTTGGGTGATATTTCCCAAATGAGTCCAGAAGATTTCTTCAAAAGCAT
TGAAAAAGCAATGATGGAAAAGGGCGATGTTAATGCACATGAAAAACTTGAAAAAATCGAAGAAATGATGGAGGAAGCTA
TCAATACCAGTCAAGAAAATGCTGAGCCTACTCAGACACAGGTTGAAAGCGAACCGCAAGTTTTAGATTATGTGCATTAT
GTTTTAGACTTTGACAACATAACAGAGGCAGTGACTTTTGCCAAAACTCTTGATTTTTCGATTGAAGCTTCGGAATTGTA
TAAAGATGGTGGCCGCTACCATATGACTATTTTATTGGATGTTCAAAATCAACCGTCTTATTATGCCAACATTATGTATG
CTCGTCTTATTGAACATGCTAGTGCAGGTACACGTACAAGAGCTTATTTGCAGGAGCATGCGAGTCAATTAATTGATGAT
AATGCTATCGAACAACTACAAAGAATTGAATTGGTAGATTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-246)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3L8GPI6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

65.462

98.419

0.644
  mecA Streptococcus thermophilus LMD-9

60.887

98.024

0.597
  mecA Streptococcus thermophilus LMG 18311

60.081

98.024

0.589
  mecA Streptococcus pneumoniae Rx1

47.619

99.605

0.474
  mecA Streptococcus pneumoniae D39

47.619

99.605

0.474
  mecA Streptococcus pneumoniae R6

47.619

99.605

0.474
  mecA Streptococcus pneumoniae TIGR4

47.619

99.605

0.474

Multiple sequence alignment