Detailed information NTG0031404

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: SEZ_RS09510
• Genome accession: NC_011134
• Coordinates: 2022054..2023277 (+)
• Length: 407 a.a.
• NCBI ID: WP_012516520.1
• Uniprot ID: A0AAW3GJZ4
• Organism: Streptococcus equi subsp. zooepidemicus MGCS10565
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2017054..2028277

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SEZ_RS09485 (Sez_1958)	-	2017748..2020333 (+)	2586	WP_012516518.1	YfhO family protein	-
SEZ_RS09505 (Sez_1959)	rlmH	2021365..2021844 (-)	480	WP_012516519.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
SEZ_RS09510 (Sez_1960)	htrA	2022054..2023277 (+)	1224	WP_012516520.1	trypsin-like peptidase domain-containing protein	Regulator
SEZ_RS09515 (Sez_1961)	spo0J	2023397..2024170 (+)	774	WP_012516521.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 407 a.a.
• Molecular weight: 42434.01 Da
• Isoelectric Point: 5.4809

>NTDB_id=31404 SEZ_RS09510 WP_012516520.1 2022054..2023277(+) (htrA) [Streptococcus equi subsp. zooepidemicus MGCS10565]
MLKSKNILKPLWVLAIGFLGGLLAALVVNGFSQNSLTSSNAKGATTTSNVSFNNTTDTTKAVKVVQDAVVSVINYQKAAS
PAISNPYINLFGEENDTSAVQKEDELSIHSEGSGVVYKKEGNTAYLVTNNHVIEGAQRIEILTADGSKIVGELVGADTYS
DLAVVKVAADKIKTIAKFADSTKINVGEVAIAIGSPLGTKYANSVTEGIVSSLSRTVTSRNEAGETISTNAIQTDAAINP
GNSGGPLINIEGQVIGINSSKISSTPTGSGGAIEGIGFAIPSSDVVTIINQLESNGAVIRPALGITMVNLSNLSTNALIQ
LNIPTSVTSGVVVASTQDGMPALGKLEQYDVITEVDGKEVSSISDLQSVLYSHEINDTIKVTFYRGTAKKKVDIKLTKTT
KDLTKKQ

Nucleotide

• Length: 1224 bp

>NTDB_id=31404 SEZ_RS09510 WP_012516520.1 2022054..2023277(+) (htrA) [Streptococcus equi subsp. zooepidemicus MGCS10565]
GTGTTAAAATCAAAAAATATATTGAAGCCCTTATGGGTTTTAGCCATTGGATTTTTAGGGGGCTTATTAGCTGCCTTAGT
TGTTAATGGATTTAGTCAGAATTCTCTAACATCTTCAAATGCAAAGGGAGCAACGACAACAAGCAACGTCAGCTTTAATA
ATACAACTGATACAACAAAGGCTGTTAAGGTGGTTCAAGATGCTGTAGTGTCTGTTATTAACTATCAAAAGGCTGCTTCG
CCTGCCATTTCAAATCCTTACATCAATCTTTTCGGAGAAGAAAATGATACCTCAGCAGTACAAAAAGAGGACGAGCTAAG
CATACACAGTGAAGGCTCGGGTGTTGTCTACAAAAAAGAAGGAAATACTGCTTATCTTGTAACCAACAATCATGTTATTG
AGGGAGCTCAACGAATTGAAATTTTAACAGCAGACGGCTCTAAGATCGTTGGAGAACTAGTTGGTGCAGACACTTATTCT
GACCTAGCTGTTGTCAAAGTTGCTGCTGATAAAATCAAAACAATAGCCAAATTTGCAGATTCAACCAAAATTAATGTTGG
AGAGGTAGCCATTGCAATTGGTAGTCCTCTTGGAACAAAATATGCCAACTCAGTGACAGAAGGGATTGTTTCAAGTCTAA
GCCGTACAGTCACTTCAAGAAATGAGGCAGGCGAGACCATCTCAACAAATGCTATCCAAACTGATGCTGCTATCAATCCA
GGTAATTCAGGTGGACCACTCATCAATATTGAAGGCCAGGTTATTGGTATCAACTCAAGTAAAATATCCTCAACACCTAC
TGGTAGCGGCGGAGCCATTGAGGGAATTGGCTTTGCTATTCCATCAAGCGATGTTGTCACCATTATTAACCAACTAGAGT
CTAACGGAGCTGTTATCAGACCAGCCTTAGGCATTACAATGGTAAACTTAAGTAATCTATCAACCAATGCATTGATTCAA
TTGAATATTCCAACAAGCGTTACCAGCGGTGTTGTCGTAGCCTCTACTCAAGATGGCATGCCTGCTCTTGGTAAATTGGA
GCAGTATGATGTCATTACTGAGGTTGACGGTAAAGAAGTCAGCTCAATTAGTGACCTACAAAGTGTCTTATATAGTCATG
AGATTAACGACACCATTAAGGTAACCTTCTACAGAGGAACTGCTAAGAAGAAAGTTGACATCAAATTAACAAAAACAACT
AAGGATCTAACTAAAAAGCAGTAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (112-257)

• PDZ domain (PDZ_2) (301-396)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	61.275	100	0.614
htrA	Streptococcus gordonii str. Challis substr. CH1	57.855	98.526	0.57
htrA	Streptococcus mitis NCTC 12261	54.66	97.543	0.533
htrA	Streptococcus pneumoniae Rx1	53.634	98.034	0.526
htrA	Streptococcus pneumoniae D39	53.634	98.034	0.526
htrA	Streptococcus pneumoniae R6	53.634	98.034	0.526
htrA	Streptococcus pneumoniae TIGR4	53.634	98.034	0.526