Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   D2E16_RS10425 Genome accession   NZ_CP032064
Coordinates   2141383..2142105 (-) Length   240 a.a.
NCBI ID   WP_024377888.1    Uniprot ID   -
Organism   Streptococcus suis strain YSJ17     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 2136383..2147105
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D2E16_RS10410 (D2E16_10725) sufD 2137502..2138764 (-) 1263 WP_192369211.1 Fe-S cluster assembly protein SufD -
  D2E16_RS10415 (D2E16_10730) sufC 2138781..2139554 (-) 774 WP_024376584.1 Fe-S cluster assembly ATPase SufC -
  D2E16_RS10420 (D2E16_10735) - 2140214..2141386 (-) 1173 WP_024377887.1 MraY family glycosyltransferase -
  D2E16_RS10425 (D2E16_10740) mecA 2141383..2142105 (-) 723 WP_024377888.1 adaptor protein MecA Regulator
  D2E16_RS10430 (D2E16_10745) - 2142233..2143072 (-) 840 WP_024377889.1 undecaprenyl-diphosphate phosphatase -
  D2E16_RS10435 (D2E16_10750) - 2143194..2144759 (+) 1566 WP_044759529.1 ABC transporter substrate-binding protein/permease -
  D2E16_RS10440 (D2E16_10755) - 2144752..2145495 (+) 744 WP_192369210.1 amino acid ABC transporter ATP-binding protein -
  D2E16_RS10445 (D2E16_10760) - 2145622..2145831 (-) 210 WP_009910800.1 hypothetical protein -
  D2E16_RS10450 (D2E16_10765) - 2145917..2146819 (-) 903 WP_002942264.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 28061.62 Da        Isoelectric Point: 4.0170

>NTDB_id=313549 D2E16_RS10425 WP_024377888.1 2141383..2142105(-) (mecA) [Streptococcus suis strain YSJ17]
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQSLNFDEFTDFSELGDVASMTPDEFFKSLEQTVREKSAPDATAVRHLEEVEQEEEVDEEEQERYIYYILEFPTIEDLFT
FVGTVDYPVEESELYKMDGYYYLTVLINVENRSKQYPGYILSRMLEFTNDTKLTRPALQEHGTLMLPLAAIEELRKVPTV

Nucleotide


Download         Length: 723 bp        

>NTDB_id=313549 D2E16_RS10425 WP_024377888.1 2141383..2142105(-) (mecA) [Streptococcus suis strain YSJ17]
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGATGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTCTATACTGTTTTGGATGAATTGGATTTACCAATGACTT
TCCGAGAAAGTGGTATGCTGAGTTTTCGTGTAACTCCGAAGCCAGATCGGGTAGACATCTTTGTTACCAAATCTGATTTG
GATCAGAGCTTGAATTTCGATGAATTTACAGATTTTTCGGAACTTGGTGATGTTGCAAGTATGACTCCAGATGAGTTTTT
CAAGAGTTTGGAGCAAACCGTTCGTGAGAAAAGTGCACCGGATGCAACAGCCGTTCGTCATTTGGAAGAGGTAGAGCAAG
AGGAAGAAGTAGATGAAGAGGAGCAGGAGCGCTATATTTACTATATTTTGGAATTTCCAACGATAGAGGATCTGTTTACT
TTTGTTGGTACGGTTGATTATCCAGTAGAAGAATCGGAATTATATAAAATGGATGGTTATTACTACTTGACCGTTCTTAT
CAATGTAGAAAATCGTTCCAAGCAGTATCCAGGCTACATTCTTTCACGAATGTTGGAATTTACCAATGATACTAAGTTGA
CCAGACCTGCTTTACAAGAGCACGGAACTTTGATGCTTCCACTTGCGGCAATCGAGGAGCTTAGGAAGGTTCCGACAGTA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

51.23

100

0.521
  mecA Streptococcus pneumoniae D39

51.23

100

0.521
  mecA Streptococcus pneumoniae R6

51.23

100

0.521
  mecA Streptococcus pneumoniae TIGR4

51.23

100

0.521
  mecA Streptococcus mutans UA159

49.59

100

0.504
  mecA Streptococcus thermophilus LMD-9

47.917

100

0.479
  mecA Streptococcus thermophilus LMG 18311

47.5

100

0.475

Multiple sequence alignment