Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   D2E16_RS01325 Genome accession   NZ_CP032064
Coordinates   256775..258928 (-) Length   717 a.a.
NCBI ID   WP_024376267.1    Uniprot ID   A0A116LDY3
Organism   Streptococcus suis strain YSJ17     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 251775..263928
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D2E16_RS01295 (D2E16_01340) - 251941..252246 (+) 306 WP_044672279.1 hypothetical protein -
  D2E16_RS01300 (D2E16_01345) - 252537..252878 (+) 342 WP_024378069.1 LytTR family DNA-binding domain-containing protein -
  D2E16_RS01305 (D2E16_01350) comE/blpR 252878..253618 (+) 741 WP_024376264.1 response regulator transcription factor Regulator
  D2E16_RS01310 (D2E16_01355) - 253628..254959 (+) 1332 WP_192369168.1 GHKL domain-containing protein -
  D2E16_RS01315 (D2E16_01360) - 255157..255306 (-) 150 WP_079267743.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  D2E16_RS01320 (D2E16_01365) - 255404..256765 (-) 1362 WP_024376266.1 bacteriocin secretion accessory protein -
  D2E16_RS01325 (D2E16_01370) comA/nlmT 256775..258928 (-) 2154 WP_024376267.1 peptide cleavage/export ABC transporter Regulator
  D2E16_RS01330 (D2E16_01375) - 259233..259463 (+) 231 WP_024376268.1 bacteriocin class II family protein -
  D2E16_RS01335 (D2E16_01380) - 259465..259656 (+) 192 WP_024376269.1 hypothetical protein -
  D2E16_RS01340 - 260159..260299 (+) 141 WP_153308671.1 hypothetical protein -
  D2E16_RS01345 - 260319..260459 (+) 141 WP_153308672.1 hypothetical protein -
  D2E16_RS01350 (D2E16_01385) - 260474..261085 (+) 612 WP_024378066.1 CPBP family intramembrane glutamic endopeptidase -
  D2E16_RS01355 (D2E16_01390) - 261247..261543 (+) 297 WP_024376271.1 bacteriocin immunity protein -
  D2E16_RS01360 (D2E16_01395) - 261687..262742 (+) 1056 WP_192369169.1 thioredoxin family protein -
  D2E16_RS01365 (D2E16_01400) - 262742..263443 (+) 702 WP_024378064.1 CPBP family intramembrane glutamic endopeptidase -
  D2E16_RS01370 - 263460..263606 (+) 147 WP_153308673.1 hypothetical protein -

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 80422.53 Da        Isoelectric Point: 7.3263

>NTDB_id=313517 D2E16_RS01325 WP_024376267.1 256775..258928(-) (comA/nlmT) [Streptococcus suis strain YSJ17]
MTKIKKTFVPQIDARDCGVAALASIAKYYGSDYSLAHLRELAKTNKEGTTALGIVKAAHEMGFETRAIQADMSLFDMTDI
PYPFIVHVNKEGKLQHYYVVYKNLKDQVLIGDPDPTVKVTKMSKERFASEWTGVAIFLAPEPSYKPHKDKKNGLLDFLPL
IFQQRTLIFYIVLASLLVTLINIAGSYYLQGILDEYIPNQMKSTLGIISIGLIITYILQQMMTFSRDYLLTVLSQRLSID
VILSYIRHIFKLPMSFFATRRTGEVISRFTDANSIIDALASTILSLFLDVTILTIVGGVLLVQNTHLFLLSLISIPIYVV
IIFAFIKPFERMNNAVMQSNSMVSSAIIEDINGIETIKSLTSEEQRYQKIDSEFVDYLEKSFTLSKYSILQSTLKQGAQL
ILNITILWLGSQLVMTGKISIGQLITFNTLLSYFTNPLENIINLQTKLQSAKVANNRLNEVYLVESEFQEGQTLTDPSFL
KGVIQFEDVSYKYGFGRDTLSDIQLTIKEGDKVSLVGISGSGKTTLAKMIVNFFEPYKGRITLNHNDLKMVDKKVLRQYI
NYLPQQAYIFSGSILDNLTLGANQTISQEDILKACEIAEIRSDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKAP
VLILDEATSGLDVLTEKKVIDNLMAMTDKTIIFVAHRLSISERTNQVIVLDQGKIIETGSHQELMSRGGFYHHLFSK

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=313517 D2E16_RS01325 WP_024376267.1 256775..258928(-) (comA/nlmT) [Streptococcus suis strain YSJ17]
ATGACCAAGATAAAGAAAACCTTCGTCCCTCAGATAGATGCCCGAGATTGCGGAGTCGCTGCTCTCGCTTCTATCGCCAA
ATACTACGGCTCAGACTACTCCTTGGCCCACTTGCGAGAGTTAGCAAAGACTAATAAAGAAGGAACAACAGCCCTCGGTA
TCGTGAAAGCTGCACATGAAATGGGCTTTGAAACCAGGGCTATCCAAGCCGATATGAGCCTCTTTGATATGACTGATATT
CCTTATCCCTTCATTGTCCATGTCAATAAAGAGGGAAAACTCCAGCATTACTATGTGGTCTATAAAAATTTGAAAGATCA
GGTCCTCATTGGCGATCCCGACCCGACTGTAAAAGTTACCAAGATGAGCAAGGAGAGATTCGCTTCCGAATGGACAGGAG
TAGCCATCTTTCTTGCACCTGAACCGAGCTATAAACCGCACAAGGATAAGAAAAATGGTCTGCTCGACTTCCTTCCCCTC
ATCTTCCAACAACGAACACTTATCTTTTATATCGTTCTAGCCAGCTTACTCGTCACCCTCATCAACATTGCTGGCTCCTA
CTATCTGCAAGGGATTTTAGATGAATACATTCCAAACCAGATGAAATCCACTCTCGGCATCATCTCCATCGGACTGATTA
TCACCTATATTCTCCAGCAAATGATGACCTTCTCCAGAGACTACCTATTAACTGTTCTCAGTCAACGGCTCAGCATTGAT
GTCATTCTCTCCTATATCCGACATATCTTCAAACTCCCCATGTCCTTCTTTGCGACACGGCGAACAGGTGAAGTCATCTC
TCGTTTTACAGATGCCAACTCAATCATCGATGCCCTAGCCTCTACAATCCTCTCCCTCTTCCTAGATGTGACTATTTTAA
CCATTGTGGGCGGGGTCTTATTGGTACAAAACACGCACCTCTTCCTCCTCTCACTGATTTCAATCCCAATCTACGTGGTC
ATCATCTTTGCCTTTATCAAACCCTTTGAAAGAATGAACAACGCTGTTATGCAGAGTAATTCGATGGTAAGCTCTGCTAT
TATCGAAGATATCAATGGTATTGAGACCATTAAGTCATTGACAAGCGAAGAACAACGCTACCAAAAGATTGACAGCGAAT
TTGTGGATTATCTGGAAAAATCCTTTACCCTCAGCAAGTATTCGATCCTGCAATCCACTCTGAAGCAAGGAGCCCAGCTG
ATCCTCAACATTACTATTCTCTGGCTCGGCTCTCAACTAGTCATGACAGGAAAAATCTCTATCGGACAACTCATCACCTT
CAATACCCTCCTCTCTTACTTCACCAATCCCTTGGAAAATATCATCAACCTCCAGACCAAGCTCCAATCTGCCAAAGTTG
CCAACAATCGCCTTAATGAAGTCTACTTGGTTGAGTCAGAATTTCAAGAAGGACAGACCCTAACCGATCCAAGCTTCTTA
AAAGGAGTTATTCAGTTTGAAGATGTTTCCTATAAATACGGATTTGGACGAGACACCCTATCTGATATTCAACTGACCAT
CAAAGAAGGGGACAAGGTTAGTTTAGTCGGTATCAGTGGTTCTGGAAAAACAACACTAGCTAAAATGATTGTGAACTTTT
TTGAACCCTATAAGGGACGCATCACGCTCAATCATAACGATCTAAAAATGGTTGATAAGAAAGTCCTACGCCAATACATC
AACTACCTCCCCCAACAAGCCTATATCTTTAGTGGCTCTATCTTGGACAATCTGACTCTCGGTGCCAACCAAACTATCAG
TCAAGAGGATATCCTAAAAGCCTGTGAAATTGCAGAAATCCGCTCGGATATTGAACAGATGCCAATGGGCTATCAGACTG
AGCTTTCTGACGGAGCTGGTCTATCTGGCGGGCAAAAACAACGGATTGCTCTTGCACGAGCCCTCTTGACCAAGGCACCT
GTGCTTATACTGGATGAAGCGACTAGCGGGCTGGATGTTCTCACCGAAAAGAAAGTCATTGACAACCTCATGGCCATGAC
AGACAAAACCATTATCTTTGTTGCCCATCGTCTCAGCATTTCCGAACGTACCAACCAAGTCATTGTGCTGGACCAGGGCA
AGATTATTGAAACCGGCTCTCACCAAGAATTAATGTCTCGCGGCGGTTTCTATCACCATTTGTTCAGTAAGTAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(500-649)

ABC transporter transmembrane region (ABC_membrane)

(168-438)

Peptidase C39 family (Peptidase_C39)

(7-142)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A116LDY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

73.202

98.884

0.724
  comA Streptococcus mitis NCTC 12261

68.776

99.163

0.682
  comA Streptococcus mitis SK321

68.073

99.163

0.675
  comA Streptococcus pneumoniae Rx1

67.792

99.163

0.672
  comA Streptococcus pneumoniae D39

67.792

99.163

0.672
  comA Streptococcus pneumoniae R6

67.792

99.163

0.672
  comA Streptococcus pneumoniae TIGR4

67.511

99.163

0.669
  comA Streptococcus gordonii str. Challis substr. CH1

67.089

99.163

0.665

Multiple sequence alignment