Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   D1O36_RS01000 Genome accession   NZ_CP031881
Coordinates   167567..168316 (+) Length   249 a.a.
NCBI ID   WP_014607893.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain ST106     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 162567..173316
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D1O36_RS10040 - 163144..163314 (+) 171 WP_011680664.1 hypothetical protein -
  D1O36_RS00975 (D1O36_00975) - 163401..163508 (+) 108 WP_011226802.1 LPXTG cell wall anchor domain-containing protein -
  D1O36_RS00980 (D1O36_00980) - 163595..164335 (-) 741 WP_002949253.1 amino acid ABC transporter ATP-binding protein -
  D1O36_RS00985 (D1O36_00985) - 164335..165885 (-) 1551 WP_134973046.1 ABC transporter substrate-binding protein/permease -
  D1O36_RS00990 (D1O36_00990) - 166088..166941 (+) 854 Protein_143 undecaprenyl-diphosphate phosphatase -
  D1O36_RS00995 (D1O36_00995) - 166993..167301 (-) 309 WP_338127636.1 DUF3021 family protein -
  D1O36_RS01000 (D1O36_01000) mecA 167567..168316 (+) 750 WP_014607893.1 adaptor protein MecA Regulator
  D1O36_RS01005 (D1O36_01005) - 168320..169477 (+) 1158 WP_134973047.1 MraY family glycosyltransferase -
  D1O36_RS01010 (D1O36_01010) sufC 169638..170408 (+) 771 WP_002947634.1 Fe-S cluster assembly ATPase SufC -
  D1O36_RS01015 (D1O36_01015) sufD 170445..171731 (+) 1287 WP_134973048.1 Fe-S cluster assembly protein SufD -
  D1O36_RS01020 (D1O36_01020) - 171761..172993 (+) 1233 WP_134973049.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29109.65 Da        Isoelectric Point: 4.0624

>NTDB_id=312309 D1O36_RS01000 WP_014607893.1 167567..168316(+) (mecA) [Streptococcus thermophilus strain ST106]
MEMKQINETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKTDL
KEDLDFNDLSDMEDYSGLSPEEFLKALEDNFMDKGDIEAHHKLEEHDKTLKEVDETMTGPAKEVAEETIREDYTHYVLAF
SDFDQVVTFAQGLKNVSVEGSELYKLGDVYYMTILLYLADEPDYYANNMYARFLEYANVADRTRPYLQEHATILMEEDAL
PVLQATKWS

Nucleotide


Download         Length: 750 bp        

>NTDB_id=312309 D1O36_RS01000 WP_014607893.1 167567..168316(+) (mecA) [Streptococcus thermophilus strain ST106]
ATGGAAATGAAACAAATAAACGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAGCT
GAAAGATTTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTATACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGTGGGATGTTGAGCTTCCGTGTCACGCCACGAAAGGATCGTGTGGATGTTTTTGTGACTAAAACAGATCTT
AAGGAAGACCTTGATTTCAATGATTTGTCAGATATGGAAGACTATTCAGGACTTTCTCCAGAAGAATTCCTCAAAGCTCT
TGAAGATAACTTTATGGATAAGGGAGATATTGAAGCCCACCATAAGCTCGAAGAGCATGATAAGACCTTGAAAGAGGTTG
ATGAGACTATGACAGGGCCGGCTAAGGAAGTGGCTGAGGAAACTATTCGTGAAGATTATACTCACTATGTCTTGGCTTTC
TCTGACTTTGATCAAGTAGTGACCTTTGCGCAAGGTTTGAAGAATGTGTCAGTGGAGGGTTCTGAACTTTATAAACTTGG
TGATGTCTACTATATGACTATCCTTCTTTACTTGGCTGATGAGCCTGATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTCCCTATCTACAAGAGCATGCAACAATCTTGATGGAAGAGGACGCCTTA
CCGGTATTACAAGCAACGAAATGGAGCTAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus thermophilus LMD-9

98.394

100

0.984
  mecA Streptococcus thermophilus LMG 18311

98.394

100

0.984
  mecA Streptococcus mutans UA159

57.787

97.992

0.566
  mecA Streptococcus pneumoniae Rx1

45.783

100

0.458
  mecA Streptococcus pneumoniae D39

45.783

100

0.458
  mecA Streptococcus pneumoniae R6

45.783

100

0.458
  mecA Streptococcus pneumoniae TIGR4

45.783

100

0.458

Multiple sequence alignment