Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   D1103_RS04690 Genome accession   NZ_CP031864
Coordinates   1037182..1038384 (-) Length   400 a.a.
NCBI ID   WP_005612209.1    Uniprot ID   A0A3G2M2S7
Organism   Actinobacillus pleuropneumoniae serovar 10 str. D13039     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1032182..1043384
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D1103_RS04665 (D1103_04715) lptE 1033982..1034476 (+) 495 WP_005597385.1 LPS assembly lipoprotein LptE -
  D1103_RS04670 (D1103_04720) holA 1034585..1035610 (+) 1026 WP_005612206.1 DNA polymerase III subunit delta -
  D1103_RS04675 (D1103_04725) yacG 1035687..1035875 (-) 189 WP_005597388.1 DNA gyrase inhibitor YacG -
  D1103_RS04680 (D1103_04730) coaE 1035857..1036495 (-) 639 WP_005612207.1 dephospho-CoA kinase -
  D1103_RS04685 (D1103_04735) - 1036517..1037155 (-) 639 WP_005604550.1 prepilin peptidase -
  D1103_RS04690 (D1103_04740) pilC 1037182..1038384 (-) 1203 WP_005612209.1 type II secretion system F family protein Machinery gene
  D1103_RS04695 (D1103_04745) pilB 1038368..1039762 (-) 1395 WP_237610862.1 GspE/PulE family protein Machinery gene
  D1103_RS04700 (D1103_04750) pilA 1039780..1040226 (-) 447 WP_005597397.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  D1103_RS04705 (D1103_04755) radA 1040408..1041787 (+) 1380 WP_005601211.1 DNA repair protein RadA Machinery gene
  D1103_RS04710 (D1103_04760) - 1041831..1042064 (-) 234 WP_005597399.1 YgjV family protein -
  D1103_RS04715 (D1103_04765) folA 1042191..1042679 (-) 489 WP_005597400.1 type 3 dihydrofolate reductase -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 45620.17 Da        Isoelectric Point: 10.2885

>NTDB_id=312126 D1103_RS04690 WP_005612209.1 1037182..1038384(-) (pilC) [Actinobacillus pleuropneumoniae serovar 10 str. D13039]
MLKVYEFHWKAKNRFQQLQKGKALACHRTELERRLLAKGYSQIRIQRNFRFVTQASSESITQVIKQLALLLNAAVPLKQA
LNMLLENTYHIRIYMWLNDLNRLIESGYTMSSSLTKLNLYLAKSEIQLVRIGEQSGRLGEILQNIAVNRYQTEKLHKKIK
KIMFYPVVTLIISVALSLAMLLFIVPQFIELYSGREKPLPLITQMLFTLSLFLQHSLLQVTIVSLLAVGFFRFFAKKYRF
LTAIKNGMLSALPIFNKIVENVRIVFFSQNLGLMLKAHIRLETALNTFLATQSQDLRLQKEIENILAQLKQGYRFSESIN
ASVFGTQVVQMLAIGEQSGNVAQMCSYIGELYRQQLDDQIELLSQLLEPILMLIIGLIIGTVLIGLYLPIFDLGGLVGGG

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=312126 D1103_RS04690 WP_005612209.1 1037182..1038384(-) (pilC) [Actinobacillus pleuropneumoniae serovar 10 str. D13039]
ATGTTGAAAGTGTATGAATTTCATTGGAAAGCTAAAAATCGTTTTCAACAACTTCAGAAAGGAAAAGCGTTAGCTTGTCA
TCGAACGGAATTGGAACGGCGTTTATTAGCAAAAGGCTATTCACAGATCCGTATCCAACGTAATTTTCGTTTTGTCACAC
AGGCTTCTTCAGAATCGATTACTCAAGTAATTAAACAGTTGGCGCTTTTACTGAATGCCGCAGTCCCTTTAAAACAAGCG
CTGAATATGTTGTTAGAAAATACTTATCATATTCGGATCTATATGTGGCTGAATGATTTAAACCGTTTGATAGAATCGGG
TTATACAATGTCGTCAAGTTTAACCAAATTGAATTTATATTTGGCGAAATCGGAAATACAGCTGGTACGGATTGGCGAAC
AAAGCGGGCGATTAGGCGAAATTTTGCAAAATATTGCGGTAAATCGCTATCAAACCGAAAAATTACATAAGAAAATAAAA
AAGATAATGTTTTATCCTGTCGTCACTTTGATTATTTCCGTTGCGCTTTCTCTCGCCATGCTCCTTTTTATCGTGCCGCA
ATTTATCGAGCTGTATTCCGGTCGTGAAAAGCCGCTTCCTTTAATTACACAAATGCTATTTACATTATCGCTCTTCTTAC
AACATTCTTTATTACAGGTAACGATAGTTAGTTTATTAGCGGTCGGTTTTTTCCGTTTTTTTGCAAAAAAATATCGATTT
TTAACCGCTATAAAAAACGGGATGTTAAGTGCTTTGCCTATTTTTAATAAGATAGTCGAAAACGTTCGTATAGTATTTTT
TAGTCAAAATCTCGGCTTGATGCTAAAAGCTCATATTCGGCTGGAAACGGCGTTAAATACCTTTCTTGCTACACAATCGC
AAGATTTGAGGTTACAAAAAGAGATAGAAAATATTTTAGCGCAATTAAAACAAGGTTATCGCTTTTCCGAAAGTATTAAT
GCGAGTGTGTTCGGTACTCAAGTAGTACAAATGCTTGCCATTGGCGAACAGAGTGGGAATGTAGCGCAGATGTGTAGCTA
TATCGGGGAGTTATATCGACAACAATTGGATGATCAGATTGAACTGTTATCGCAGCTGCTTGAGCCGATCTTAATGCTGA
TTATCGGATTAATTATCGGTACGGTTTTGATCGGATTATATTTACCGATTTTTGATTTAGGCGGACTAGTCGGAGGCGGT
TAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(267-389)

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3G2M2S7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Glaesserella parasuis strain SC1401

49.874

99.25

0.495
  pilC Haemophilus influenzae Rd KW20

40

100

0.4
  pilC Haemophilus influenzae 86-028NP

39

100

0.39

Multiple sequence alignment