Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   D1110_RS04670 Genome accession   NZ_CP031856
Coordinates   1018661..1019863 (-) Length   400 a.a.
NCBI ID   WP_237586308.1    Uniprot ID   -
Organism   Actinobacillus pleuropneumoniae strain 16287-1     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1013661..1024863
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D1110_RS04645 (D1110_04645) lptE 1015461..1015955 (+) 495 WP_005597385.1 LPS assembly lipoprotein LptE -
  D1110_RS04650 (D1110_04650) holA 1016064..1017089 (+) 1026 WP_237586307.1 DNA polymerase III subunit delta -
  D1110_RS04655 (D1110_04655) yacG 1017166..1017354 (-) 189 WP_005597388.1 DNA gyrase inhibitor YacG -
  D1110_RS04660 (D1110_04660) coaE 1017336..1017974 (-) 639 WP_005601202.1 dephospho-CoA kinase -
  D1110_RS04665 (D1110_04665) - 1017996..1018634 (-) 639 WP_005604550.1 prepilin peptidase -
  D1110_RS04670 (D1110_04670) pilC 1018661..1019863 (-) 1203 WP_237586308.1 type II secretion system F family protein Machinery gene
  D1110_RS04675 (D1110_04675) pilB 1019847..1021241 (-) 1395 WP_237586309.1 GspE/PulE family protein Machinery gene
  D1110_RS04680 (D1110_04680) pilA 1021259..1021705 (-) 447 WP_005597397.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  D1110_RS04685 (D1110_04685) radA 1021887..1023266 (+) 1380 WP_005601211.1 DNA repair protein RadA Machinery gene
  D1110_RS04690 (D1110_04690) - 1023310..1023543 (-) 234 WP_005597399.1 YgjV family protein -
  D1110_RS04695 (D1110_04695) folA 1023670..1024158 (-) 489 WP_005597400.1 type 3 dihydrofolate reductase -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 45636.26 Da        Isoelectric Point: 10.4199

>NTDB_id=311942 D1110_RS04670 WP_237586308.1 1018661..1019863(-) (pilC) [Actinobacillus pleuropneumoniae strain 16287-1]
MLKVYEFHWKAKNRFQQLQKGKALACHRTELERRLLAKGYSQIRIQRNFRFVTRASSESITQVIKQLALLLNAAVPLKQA
LNMLLENTYHIRIYMWLNDLKRLIESGYTMSSSLTKLNLYLAKSEIQLVRIGEQSGRLGEILQNIAVNRHQTEKLHKKIK
KIMFYPVVTLIISVALSLAMLLFIVPQFIELYSGREKPLPLITQMLFTLSLFLQHSLLQVTIVSLLAVGFFRFFAKKYRF
LTAIKNGMLSALPIFNKIVENVRIVFFSQNLGLMLKAHIRLETALNTFLATQSQDLRLQKEIENILAQLKQGYRFSESIN
ASVFGTQVVQMLAIGEQSGNVAQMCSYIGELYRQQLDDQIELLSQLLEPILMLIIGLIIGTVLIGLYLPIFDLGGLVGGG

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=311942 D1110_RS04670 WP_237586308.1 1018661..1019863(-) (pilC) [Actinobacillus pleuropneumoniae strain 16287-1]
ATGTTGAAAGTGTATGAATTTCATTGGAAAGCTAAAAATCGTTTTCAACAACTTCAGAAAGGAAAAGCGTTAGCTTGTCA
TCGAACGGAATTGGAACGGCGTTTATTAGCAAAAGGCTATTCACAGATCCGTATCCAACGTAATTTTCGTTTTGTCACAC
GGGCTTCTTCAGAATCGATTACTCAAGTAATTAAACAGTTGGCGCTTTTACTGAATGCCGCAGTCCCTTTAAAACAAGCG
CTGAATATGTTGTTAGAAAATACTTATCATATTCGGATCTATATGTGGCTGAATGATTTAAAGCGTTTGATAGAATCGGG
TTATACAATGTCGTCAAGTTTAACCAAATTGAATTTATATTTGGCGAAATCGGAAATACAGCTGGTACGGATTGGCGAAC
AAAGCGGGCGATTAGGCGAAATTTTGCAAAATATTGCGGTAAATCGCCATCAAACCGAAAAATTACATAAGAAAATAAAA
AAGATAATGTTTTATCCTGTCGTCACTTTGATTATTTCCGTTGCGCTTTCTCTCGCCATGCTCCTTTTTATCGTGCCGCA
ATTTATCGAGCTGTATTCCGGTCGTGAAAAGCCGCTTCCTTTAATTACACAAATGCTATTTACATTATCGCTCTTCTTAC
AACATTCTTTATTACAGGTAACGATAGTCAGTTTATTAGCGGTCGGTTTTTTCCGTTTTTTTGCAAAAAAATATCGATTT
TTAACCGCTATAAAAAACGGGATGTTAAGTGCTTTGCCTATTTTTAATAAGATAGTCGAAAACGTTCGTATAGTATTTTT
TAGTCAAAATCTCGGCTTGATGCTAAAAGCTCATATTCGGCTGGAAACGGCGTTAAATACCTTTCTTGCTACACAATCGC
AAGATTTGAGGTTACAAAAAGAGATAGAAAATATTTTAGCGCAATTAAAACAAGGTTATCGCTTTTCCGAAAGTATTAAT
GCGAGTGTGTTCGGTACTCAAGTAGTACAAATGCTTGCCATTGGCGAACAGAGTGGGAATGTAGCGCAGATGTGTAGCTA
TATCGGGGAGTTATATCGACAACAATTGGATGATCAGATTGAACTGTTATCGCAGCTGCTTGAGCCGATCTTAATGCTGA
TTATCGGATTAATTATCGGTACGGTTTTGATCGGATTATATTTACCGATTTTTGATTTAGGCGGACTAGTCGGAGGCGGT
TAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(267-389)

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Glaesserella parasuis strain SC1401

49.874

99.25

0.495
  pilC Haemophilus influenzae Rd KW20

40

100

0.4
  pilC Haemophilus influenzae 86-028NP

39

100

0.39

Multiple sequence alignment