Detailed information NTG0311450

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: D0638_RS12760
• Genome accession: NZ_CP031785
• Coordinates: 2495952..2498144 (-)
• Length: 730 a.a.
• NCBI ID: WP_149350261.1
• Uniprot ID: -
• Organism: Lacticaseibacillus paracasei strain 10266
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 2490952..2503144

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D0638_RS12730 (D0638_12770)	-	2491118..2491402 (-)	285	WP_003580845.1	bacteriocin immunity protein	-
D0638_RS12735 (D0638_12775)	-	2491595..2491891 (-)	297	WP_003580847.1	bacteriocin immunity protein	-
D0638_RS12740 (D0638_12780)	-	2491993..2493348 (-)	1356	WP_003567335.1	threonine/serine exporter ThrE family protein	-
D0638_RS12745 (D0638_12785)	-	2493654..2493965 (-)	312	WP_003580849.1	hypothetical protein	-
D0638_RS12750 (D0638_12790)	-	2494038..2494388 (-)	351	WP_003567340.1	hypothetical protein	-
D0638_RS12755 (D0638_12795)	-	2494562..2495941 (-)	1380	WP_003585563.1	bacteriocin secretion accessory protein	-
D0638_RS12760 (D0638_12800)	comA	2495952..2498144 (-)	2193	WP_149350261.1	peptide cleavage/export ABC transporter	Regulator
D0638_RS12765 (D0638_12805)	-	2498610..2498747 (-)	138	WP_003571414.1	bacteriocin-like peptide, LSEI_2386 family	-
D0638_RS12770 (D0638_12810)	-	2498937..2500235 (+)	1299	WP_003580853.1	GHKL domain-containing protein	-
D0638_RS12775 (D0638_12815)	-	2500240..2501046 (+)	807	WP_003567351.1	LytTR family DNA-binding domain-containing protein	-
D0638_RS12780 (D0638_12820)	-	2501408..2501605 (-)	198	WP_016383118.1	hypothetical protein	-
D0638_RS12785 (D0638_12825)	-	2502152..2502391 (+)	240	WP_003580868.1	hypothetical protein	-
D0638_RS12790 (D0638_12830)	-	2502651..2502824 (-)	174	WP_032675994.1	bacteriocin	-
D0638_RS12795 (D0638_12835)	-	2502859..2503047 (-)	189	WP_003567358.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-

Sequence

Protein

• Length: 730 a.a.
• Molecular weight: 81151.37 Da
• Isoelectric Point: 6.8360

>NTDB_id=311450 D0638_RS12760 WP_149350261.1 2495952..2498144(-) (comA) [Lacticaseibacillus paracasei strain 10266]
MIKYNLKLGQAQYYKRYYTPQVDERDCGVAALNMLLQFNGSDYSLAHLRQLAKTDQEGTTALGIVRAAQALHFETKAVKA
DMTLFDLDDVPYPFLVHVLKRGELLHYYVVFKATKDHILIGDPDPSVAMTWLPKERFAKEWSGVAIFIAPEPQYQPRKED
KGSLFAFVPILARQKGIIANIIVAAVLITLISIVGSYFLQSIIDTYIPNGMRTTLGMIASGLILAYVLQSVLTYGQNFLM
AVLGQRLSIDVILGYVRHLYELPMSFFSTRRTGEIVSRFSDANKIIDALANTIMTLFLDIWIVLILGIVLGIQNTTLFLV
SLIAVPCYLVIVFAFQRPFNRLNQETMGSNAILSSSIIEDLNGIETIKSLTGEKVSYERVDREFVTYLKKSFNYTKADQL
QQAIKGLLQLVLNVVVLWIGASLVMANKMSLGQMLTFNALLAYFTNPLESIINLQPKLQMAKVANNRLNEVYLVESEFKE
QRTLNDRHLIDGAINVTDVSFKYGFGQDVLKQINLEIPENAKYTIVGMSGSGKLTLAKLLVGFYPVDTGKGKITFNGVPI
SDVDLTTLRQYIEYVPQDPFIFSGSVIENLTLGSRSNITEADIEAACSVAEIAGDISNLPQIWQTKLSESGSILSGGQKQ
RLAIARALLSPAKVLIFDESTSSLDTITERKIVDRLLAMTDRTIIFVAHGLTIAAKTEQIVVMDHGAIVEQGNHAELLAK
QGYYARLVSE

Nucleotide

• Length: 2193 bp

>NTDB_id=311450 D0638_RS12760 WP_149350261.1 2495952..2498144(-) (comA) [Lacticaseibacillus paracasei strain 10266]
ATGATCAAATACAACCTAAAGCTCGGCCAAGCACAGTATTACAAGCGTTACTACACGCCTCAGGTGGATGAGCGCGATTG
CGGGGTTGCGGCGCTTAATATGTTGCTGCAATTTAATGGCTCGGATTATTCGCTAGCGCATCTGCGACAGTTGGCGAAGA
CGGATCAGGAAGGGACGACGGCATTAGGGATTGTCCGCGCTGCTCAGGCGCTTCATTTTGAAACCAAGGCGGTCAAGGCG
GATATGACGCTGTTTGATCTTGATGATGTTCCTTATCCGTTTCTTGTCCATGTTTTGAAGCGTGGCGAGTTGCTTCATTA
TTATGTGGTGTTTAAGGCGACAAAGGATCATATCTTGATTGGCGATCCTGATCCATCAGTAGCGATGACCTGGCTTCCCA
AAGAGCGCTTTGCGAAGGAGTGGTCGGGGGTCGCTATTTTTATTGCGCCAGAACCGCAATATCAACCACGCAAAGAGGAC
AAAGGCAGTCTCTTTGCGTTTGTGCCGATACTAGCGCGACAAAAAGGGATCATTGCCAATATTATTGTCGCCGCTGTGTT
GATTACGTTGATTAGTATTGTCGGGTCTTATTTTCTTCAGTCGATTATTGATACTTATATTCCAAACGGGATGCGCACAA
CTTTGGGAATGATTGCCAGTGGTCTCATCCTTGCTTATGTCCTGCAGTCGGTTTTAACCTATGGGCAAAATTTTTTGATG
GCTGTTTTAGGACAGCGTTTGTCGATTGATGTCATTTTGGGTTACGTTAGGCATCTTTATGAATTACCGATGTCCTTCTT
TTCCACGCGTCGGACTGGGGAGATTGTATCGCGGTTTTCCGATGCTAATAAGATTATTGATGCGCTGGCAAACACAATTA
TGACCTTGTTTCTTGATATTTGGATTGTCTTAATTTTAGGGATCGTGTTAGGCATTCAAAACACCACCTTATTCTTGGTG
TCTTTAATTGCTGTGCCTTGTTATTTGGTGATTGTGTTCGCTTTTCAGCGGCCATTTAATCGACTGAATCAAGAGACGAT
GGGAAGCAATGCCATATTGAGTTCATCCATTATCGAGGATTTGAACGGGATTGAGACGATTAAATCACTGACCGGTGAGA
AAGTCAGTTATGAACGGGTTGACCGTGAATTCGTCACGTATTTGAAAAAGTCGTTCAATTATACAAAAGCTGATCAACTG
CAGCAGGCGATCAAGGGACTGCTGCAGTTGGTTTTGAATGTGGTCGTGCTGTGGATTGGTGCGAGTTTGGTGATGGCTAA
CAAGATGAGTCTAGGACAGATGCTGACGTTCAATGCGTTGTTGGCATATTTCACTAATCCGTTAGAAAGCATCATTAATT
TGCAACCAAAATTGCAAATGGCCAAAGTCGCGAATAACCGGCTGAATGAAGTGTATTTGGTTGAATCGGAGTTTAAAGAA
CAGCGAACTTTGAATGATCGGCATTTAATTGATGGCGCTATCAACGTGACCGATGTGTCTTTTAAGTATGGTTTTGGGCA
AGATGTTTTGAAACAAATCAACCTTGAAATCCCGGAGAATGCCAAATACACCATTGTCGGCATGAGTGGATCAGGGAAAT
TGACCTTAGCCAAGTTGCTAGTAGGTTTCTATCCAGTGGACACTGGCAAAGGGAAAATCACATTTAATGGGGTTCCCATC
AGTGATGTTGATCTGACAACGTTACGACAATATATCGAGTATGTACCACAAGATCCGTTTATTTTTTCTGGCTCAGTCAT
TGAAAACTTAACGTTGGGTAGCCGTTCGAATATCACTGAAGCCGATATTGAAGCTGCCTGTTCAGTGGCGGAAATTGCCG
GAGATATTTCGAATTTGCCGCAGATATGGCAGACCAAACTTTCTGAAAGCGGCAGTATTTTATCGGGTGGACAAAAGCAG
CGCCTAGCAATTGCCCGCGCGTTATTATCACCGGCAAAAGTGTTGATTTTTGATGAATCGACCAGCAGTTTAGATACGAT
CACCGAGCGAAAAATTGTTGATCGGTTGTTAGCGATGACTGATCGAACCATTATTTTTGTGGCTCATGGGCTCACTATTG
CTGCTAAAACGGAACAGATTGTGGTCATGGATCATGGTGCGATTGTTGAACAAGGAAATCATGCTGAGTTATTGGCCAAA
CAAGGCTATTATGCTCGGTTGGTAAGTGAGTGA

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (180-448)

• Peptidase C39 family (Peptidase_C39) (16-152)

• ABC transporter (ABC_tran) (510-662)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	58.914	98.356	0.579
comA	Streptococcus pneumoniae Rx1	58.357	98.356	0.574
comA	Streptococcus pneumoniae D39	58.357	98.356	0.574
comA	Streptococcus pneumoniae R6	58.357	98.356	0.574
comA	Streptococcus mitis SK321	58.217	98.356	0.573
comA	Streptococcus pneumoniae TIGR4	57.939	98.356	0.57
comA	Streptococcus gordonii str. Challis substr. CH1	56.825	98.356	0.559
comA/nlmT	Streptococcus mutans UA159	54.571	98.904	0.54