Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   DDV21_RS09885 Genome accession   NZ_CP031733
Coordinates   2066796..2067551 (-) Length   251 a.a.
NCBI ID   WP_116878445.1    Uniprot ID   A0A372KKX1
Organism   Streptococcus chenjunshii strain Z15     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 2061796..2072551
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DDV21_RS09865 (DDV21_009865) - 2062051..2063277 (-) 1227 WP_116878449.1 cysteine desulfurase -
  DDV21_RS09870 (DDV21_009870) sufD 2063315..2064577 (-) 1263 WP_116878448.1 Fe-S cluster assembly protein SufD -
  DDV21_RS09875 (DDV21_009875) sufC 2064618..2065388 (-) 771 WP_116878447.1 Fe-S cluster assembly ATPase SufC -
  DDV21_RS09880 (DDV21_009880) - 2065616..2066794 (-) 1179 WP_116878446.1 MraY family glycosyltransferase -
  DDV21_RS09885 (DDV21_009885) mecA 2066796..2067551 (-) 756 WP_116878445.1 adaptor protein MecA Regulator
  DDV21_RS09890 (DDV21_009890) - 2067738..2068577 (-) 840 WP_116878444.1 undecaprenyl-diphosphate phosphatase -
  DDV21_RS09895 (DDV21_009895) - 2068636..2070555 (-) 1920 WP_116878443.1 DUF2207 domain-containing protein -
  DDV21_RS09900 (DDV21_009900) - 2070690..2072246 (+) 1557 WP_116878442.1 ABC transporter substrate-binding protein/permease -

Sequence

Protein


Download         Length: 251 a.a.        Molecular weight: 28896.66 Da        Isoelectric Point: 4.1895

>NTDB_id=310859 DDV21_RS09885 WP_116878445.1 2066796..2067551(-) (mecA) [Streptococcus chenjunshii strain Z15]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYTIMDELDLPDNFKDTGMLSFRVTPRKDQIDVFVTKSDL
NKDLNLEDLAEFGDVSQMTPEDFFKTLEKSMREKGDTEAHERLEKIEEMMEEAADSALGASKSAKDGEKEEEPADYIHYV
LDFPNLKTAVAFAKTVDFDIEASEFYKEGASYHLAVLLNLVNKPSYYANIIYARLLEHAWPGTKTRAYLQEHGVELLMTD
AVQQLQMIELV

Nucleotide


Download         Length: 756 bp        

>NTDB_id=310859 DDV21_RS09885 WP_116878445.1 2066796..2067551(-) (mecA) [Streptococcus chenjunshii strain Z15]
ATGGAAATGAAACAGATAAGTGAGACAACCTTAAAAATCACCATCAGCATGGACGATTTGGAAGAACGCGGGATGGAGCT
GAAGGACTTTCTGATTCCTCAGGAAAAGACAGAAGAGTTTTTCTATACCATCATGGATGAGCTCGACTTGCCCGATAATT
TTAAAGATACGGGCATGCTGAGCTTTCGTGTGACTCCCAGAAAAGATCAGATTGATGTGTTTGTAACAAAGTCAGATTTG
AATAAAGATCTTAACTTAGAAGATTTGGCAGAGTTTGGCGATGTATCGCAGATGACACCCGAAGATTTCTTCAAGACTTT
GGAAAAATCTATGCGGGAAAAAGGCGATACGGAAGCGCATGAGAGACTGGAAAAAATTGAAGAGATGATGGAGGAAGCCG
CAGATTCTGCACTCGGAGCCTCCAAATCTGCAAAAGACGGTGAAAAAGAGGAGGAACCGGCCGATTATATTCATTATGTG
CTCGATTTTCCTAATTTAAAAACAGCTGTTGCTTTTGCAAAGACAGTCGATTTTGATATTGAAGCTTCTGAATTTTATAA
GGAAGGAGCGTCTTACCATCTGGCTGTTCTGCTTAACTTAGTGAATAAACCGAGTTATTATGCCAATATAATATACGCTC
GTCTCTTAGAGCATGCTTGGCCGGGAACTAAGACGCGTGCTTATCTGCAGGAACATGGCGTAGAGCTGCTGATGACTGAT
GCGGTTCAGCAATTACAAATGATTGAGTTGGTATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A372KKX1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

67.339

98.805

0.665
  mecA Streptococcus thermophilus LMD-9

56.275

98.406

0.554
  mecA Streptococcus thermophilus LMG 18311

55.466

98.406

0.546
  mecA Streptococcus pneumoniae Rx1

48.606

100

0.486
  mecA Streptococcus pneumoniae D39

48.606

100

0.486
  mecA Streptococcus pneumoniae R6

48.606

100

0.486
  mecA Streptococcus pneumoniae TIGR4

48.207

100

0.482

Multiple sequence alignment