Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   DDV21_RS09130 Genome accession   NZ_CP031733
Coordinates   1908068..1909966 (-) Length   632 a.a.
NCBI ID   WP_116878870.1    Uniprot ID   A0A372KJP6
Organism   Streptococcus chenjunshii strain Z15     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 1903068..1914966
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DDV21_RS09105 (DDV21_009105) - 1903312..1903674 (-) 363 WP_116878865.1 S1 RNA-binding domain-containing protein -
  DDV21_RS09110 (DDV21_009110) - 1903674..1905074 (-) 1401 WP_116878866.1 Cof-type HAD-IIB family hydrolase -
  DDV21_RS09115 (DDV21_009115) - 1905115..1905756 (-) 642 WP_116878867.1 response regulator transcription factor -
  DDV21_RS09120 (DDV21_009120) - 1905839..1906828 (-) 990 WP_116878868.1 sensor histidine kinase -
  DDV21_RS09125 (DDV21_009125) liaF 1906825..1907523 (-) 699 WP_116878869.1 cell wall-active antibiotics response protein LiaF -
  DDV21_RS09130 (DDV21_009130) pknB 1908068..1909966 (-) 1899 WP_116878870.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  DDV21_RS09135 (DDV21_009135) - 1909966..1910703 (-) 738 WP_116878871.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  DDV21_RS09140 (DDV21_009140) rsmB 1910740..1912065 (-) 1326 WP_116878872.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  DDV21_RS09145 (DDV21_009145) fmt 1912058..1912990 (-) 933 WP_116878873.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 632 a.a.        Molecular weight: 68620.59 Da        Isoelectric Point: 4.5170

>NTDB_id=310855 DDV21_RS09130 WP_116878870.1 1908068..1909966(-) (pknB) [Streptococcus chenjunshii strain Z15]
MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEEVAIKVLRTNYQTDQVAITRFQREARAMAELNHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKYIQEHAPLSNNEVVRIMEEVLSAMTLAHQQGIVHRDLKPQNILLTKDGTVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIMLFEMLTGYIPYDGDSAVTIALQHFQKPLPSIIELNKNVP
QALENVVIKATAKKLSDRYSSTFEMSRDLMTALSYNRSREPKLVFSDHENTKTLPKVIPAPAASAAEENAEENKTVQQAS
TAADAKAKKKKAKKQKRLFSTIAKIAFAVFIVALAWLAFVILRNPSTVTVPDVTGTTLSAAEKRIEDSGLRVGDVRKVDS
AEVDKGRVVRTDPAAGSSKKEGTRVDIYVSTGNSAFTMEDYVGQNYEKVVSDLKDTYGVSASQIEIKEVAASDYDYYDDD
IIVSQTPAAGETFNPAGDDKIVFEVTSSNTVTMPDLTDYTYGDALELLTSLGISSSRIKTYINGDTEVTSPSTSAVISSQ
SPEAGYEVVLSGNGEIILYLYSSQGGGNYSDRSSSPLDDSSSSSDSSSDEEPDQSSDTSSEDSDSSSSGSEG

Nucleotide


Download         Length: 1899 bp        

>NTDB_id=310855 DDV21_RS09130 WP_116878870.1 1908068..1909966(-) (pknB) [Streptococcus chenjunshii strain Z15]
ATGATTCAGATTGGCAAATTATTCGCTGGTCGTTATCGTATTTTGAAATCCATTGGACGGGGCGGAATGGCAGATGTTTA
TTTGGCTAATGACCTCATTTTAGATAATGAAGAAGTTGCTATCAAAGTATTGAGGACGAACTATCAGACAGATCAGGTCG
CTATAACGCGTTTTCAAAGAGAAGCACGAGCCATGGCCGAATTGAACCACCCTAATATTGTTGCTATTCGTGATATTGGA
GAAGAAGACGGCCAGCAATTTTTAGTAATGGAATATGTTGATGGATCGGATCTAAAAAAATATATTCAAGAGCACGCTCC
TTTATCAAATAATGAAGTTGTCAGAATCATGGAAGAAGTACTGTCTGCTATGACACTGGCGCATCAGCAGGGTATTGTTC
ACCGGGATCTCAAGCCGCAGAATATTTTACTGACAAAAGACGGTACTGTAAAGGTTACTGACTTTGGTATAGCGGTTGCT
TTTGCGGAAACAAGCTTGACACAGACAAACTCAATGCTCGGAAGTGTCCATTACCTATCTCCCGAGCAGGCTCGCGGTTC
TAAAGCAACTGTTCAAAGTGATATCTATGCTATGGGAATTATGCTGTTTGAAATGCTGACCGGCTATATTCCTTATGATG
GTGACAGTGCGGTCACTATCGCGCTGCAGCATTTTCAAAAACCGCTGCCGTCCATCATTGAACTCAATAAAAATGTTCCT
CAGGCTCTCGAAAATGTAGTGATAAAGGCAACAGCTAAAAAACTAAGCGACCGCTATTCATCCACATTTGAGATGAGCCG
GGACTTGATGACAGCGCTCAGCTATAATCGCAGCCGTGAGCCGAAATTAGTTTTCAGTGATCATGAAAATACGAAAACGT
TGCCTAAAGTTATCCCGGCTCCTGCCGCTTCTGCAGCAGAAGAAAATGCTGAGGAAAACAAAACAGTTCAGCAAGCGAGT
ACAGCTGCTGATGCTAAAGCTAAAAAGAAGAAGGCTAAAAAACAAAAGCGTCTCTTTAGTACAATTGCAAAAATTGCTTT
TGCTGTTTTTATTGTTGCTCTTGCCTGGCTGGCTTTTGTTATTTTGCGCAATCCCTCAACAGTGACTGTCCCTGATGTTA
CAGGAACAACATTGTCAGCTGCTGAGAAAAGAATTGAGGATTCCGGCCTTAGAGTAGGAGATGTCCGTAAAGTAGACAGT
GCTGAAGTAGACAAGGGAAGGGTTGTACGGACCGATCCTGCTGCCGGCTCTTCAAAAAAAGAGGGGACACGTGTGGATAT
TTATGTGTCAACCGGCAATTCAGCCTTCACTATGGAAGATTATGTTGGACAGAATTATGAAAAGGTTGTGTCAGACTTGA
AAGATACTTATGGGGTATCGGCTTCACAGATTGAAATTAAAGAAGTTGCTGCAAGCGATTATGACTATTATGATGATGAT
ATTATTGTCAGCCAAACACCGGCTGCCGGAGAAACATTTAATCCTGCCGGCGATGATAAGATTGTCTTTGAAGTGACCAG
CAGCAATACCGTAACGATGCCTGATTTGACGGATTACACTTACGGTGATGCGCTGGAATTGCTGACCAGTCTCGGTATCT
CATCATCTCGCATCAAGACTTATATTAATGGGGATACAGAAGTTACCTCTCCATCAACCAGCGCTGTCATTTCCAGCCAA
AGTCCGGAAGCGGGCTATGAAGTTGTGCTCTCAGGAAACGGTGAAATCATTCTCTACCTCTACTCAAGTCAAGGCGGCGG
CAATTATTCAGACAGGTCGTCCTCGCCTTTGGATGACAGTTCCTCTTCCAGTGACAGTTCCTCTGACGAAGAACCCGATC
AGAGTTCAGATACATCTTCGGAAGATTCTGACAGCTCGTCATCTGGTTCAGAAGGCTAG

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(511-581)

PASTA domain (PASTA)

(368-431)

PASTA domain (PASTA)

(437-506)

Protein kinase domain (Pkinase)

(12-260)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A372KJP6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

65.983

92.563

0.611
  stkP/pknB Streptococcus salivarius strain HSISS4

62.075

93.038

0.578
  stkP Streptococcus pneumoniae TIGR4

61.79

72.468

0.448
  stkP Streptococcus pneumoniae D39

61.572

72.468

0.446
  stkP Streptococcus pneumoniae R6

61.572

72.468

0.446
  stkP Streptococcus pneumoniae Rx1

61.354

72.468

0.445

Multiple sequence alignment