Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   DDV21_RS08545 Genome accession   NZ_CP031733
Coordinates   1796083..1798230 (-) Length   715 a.a.
NCBI ID   WP_116877980.1    Uniprot ID   A0A372KM53
Organism   Streptococcus chenjunshii strain Z15     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1791083..1803230
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DDV21_RS08520 (DDV21_008520) rplA 1792088..1792777 (-) 690 WP_116877976.1 50S ribosomal protein L1 -
  DDV21_RS08525 (DDV21_008525) rplK 1792877..1793302 (-) 426 WP_116877977.1 50S ribosomal protein L11 -
  DDV21_RS08530 (DDV21_008530) - 1793465..1793815 (+) 351 WP_116877978.1 DUF3397 domain-containing protein -
  DDV21_RS08535 (DDV21_008535) - 1793937..1794449 (-) 513 WP_162886302.1 cyclophilin-like fold protein -
  DDV21_RS08540 (DDV21_008540) - 1794689..1796071 (-) 1383 WP_116877979.1 bacteriocin secretion accessory protein -
  DDV21_RS08545 (DDV21_008545) comA/nlmT 1796083..1798230 (-) 2148 WP_116877980.1 peptide cleavage/export ABC transporter Regulator
  DDV21_RS08550 (DDV21_008550) - 1798339..1798599 (-) 261 WP_241964662.1 hypothetical protein -
  DDV21_RS08555 (DDV21_008555) - 1798827..1799063 (+) 237 WP_116877981.1 ComC/BlpC family peptide pheromone/bacteriocin -
  DDV21_RS08560 (DDV21_008560) - 1799153..1799464 (+) 312 WP_116877982.1 hypothetical protein -
  DDV21_RS11945 - 1799651..1799818 (-) 168 Protein_1640 IS3 family transposase -
  DDV21_RS08565 (DDV21_008565) - 1799988..1800215 (+) 228 WP_116877983.1 Blp family class II bacteriocin -
  DDV21_RS08570 (DDV21_008570) - 1800235..1800465 (+) 231 WP_116877984.1 Blp family class II bacteriocin -
  DDV21_RS08575 (DDV21_008575) - 1800469..1800855 (+) 387 WP_241964663.1 hypothetical protein -
  DDV21_RS08580 (DDV21_008580) - 1801118..1801336 (+) 219 WP_116877985.1 leucocin A/sakacin P family class II bacteriocin -
  DDV21_RS08585 (DDV21_008585) - 1801336..1801632 (+) 297 WP_116877986.1 bacteriocin immunity protein -
  DDV21_RS08590 (DDV21_008590) - 1801836..1802069 (+) 234 WP_116877987.1 Blp family class II bacteriocin -
  DDV21_RS08595 (DDV21_008595) - 1802093..1802284 (+) 192 WP_116877988.1 bacteriocin -
  DDV21_RS08605 (DDV21_008605) - 1802543..1802851 (+) 309 WP_116877989.1 bacteriocin immunity protein -

Sequence

Protein


Download         Length: 715 a.a.        Molecular weight: 79764.39 Da        Isoelectric Point: 7.0445

>NTDB_id=310848 DDV21_RS08545 WP_116877980.1 1796083..1798230(-) (comA/nlmT) [Streptococcus chenjunshii strain Z15]
MKRYKYVSQIDLRDCGVAALASVAKHYGSDFSLAHLRELAKTTKEGTTALGIVEAAKKMGFETRAVQANMELFDMADIPC
PFIVHVNKEGKLQHYYVVYNVKKTNLIIGDPDPAVGVTKMSKEHFAEEWTGVAIFLAPAPYYKPHKDKKNGLMSFLPIIF
KQKALLTYIVLASLLVTLINIIGSYYLQGILDEYIPNQLQSTLGIVSIGLVVTYVLQQVMSFSQNYLLVVLSQRLTIDVI
LSYIRHIFELPMSFFATRRTGEVMSRFTDANSIIDALASTILSLFLDVSILFIVGSVLVLQNTHLFFITLTALPVYAIII
LAFMKPFERMNHDVMQANAMVSSAIIEDINGIETVKSLTSEETRYQNIDREFVDYLDKSFALNKYEAVQGALKQGAQLIL
NVAVLWYGSRLVIAGSISVGQLITYNTLLSYFTRPMENIINLQTKLQSAKVANKRLNEVYLVSSEFDGGQILNDKQFLKG
DIIFDDVSYKYGFGRDTLSHVNLRIKEGEKVSLVGISGSGKTTLAKMIVNFYTPNQGQITLGGYDLKTIDKKALRHYINY
LPQQSYVFSGTVLENLTLGASDNMTQEDIFKACDIAEIRSDIESMPMAYHTELSDGAGLSGGQKQRLALARALLTQAPVL
ILDEATSGLDALTEKRVIDNLLSLTDRTIIFVAHRLSIAERSDRIIVIDQGQVAEEGSHRQLIQAQGFYAHLFQK

Nucleotide


Download         Length: 2148 bp        

>NTDB_id=310848 DDV21_RS08545 WP_116877980.1 1796083..1798230(-) (comA/nlmT) [Streptococcus chenjunshii strain Z15]
ATGAAAAGATACAAATATGTTAGTCAGATTGATTTACGAGATTGCGGTGTGGCAGCTTTGGCATCAGTTGCCAAGCATTA
TGGTTCAGATTTCTCACTGGCTCACTTAAGAGAGCTGGCGAAAACAACTAAGGAAGGGACAACAGCCTTAGGTATTGTTG
AAGCCGCTAAGAAAATGGGCTTTGAAACACGTGCCGTTCAAGCCAATATGGAACTGTTTGACATGGCTGACATTCCCTGT
CCCTTTATTGTTCATGTCAACAAAGAGGGAAAACTTCAGCATTACTATGTTGTTTACAACGTTAAAAAGACTAACCTTAT
CATCGGTGACCCTGATCCAGCTGTTGGGGTCACTAAAATGTCTAAGGAACATTTTGCTGAAGAATGGACTGGTGTCGCTA
TCTTTTTAGCGCCCGCTCCATACTACAAGCCTCATAAGGATAAAAAGAATGGTTTAATGAGTTTTTTGCCCATTATTTTT
AAGCAAAAAGCCCTGCTGACCTATATTGTGCTCGCCAGCCTCCTAGTCACTTTAATCAATATCATTGGTTCCTATTATTT
ACAAGGAATTTTAGATGAATATATTCCTAATCAGCTGCAGTCTACTCTTGGTATTGTGTCTATCGGACTGGTTGTTACCT
ATGTCCTGCAGCAAGTCATGAGTTTTTCGCAGAACTATCTGCTAGTTGTTCTAAGTCAACGCTTGACGATTGATGTGATT
TTATCTTATATCCGCCATATTTTTGAATTACCCATGTCCTTTTTTGCGACAAGACGGACTGGTGAGGTCATGTCACGTTT
TACCGATGCTAATTCAATTATTGATGCATTGGCTTCGACGATTTTATCGCTGTTTTTAGATGTGAGTATTCTCTTTATTG
TCGGAAGTGTCCTTGTCCTTCAAAATACCCATCTCTTTTTTATCACTTTAACAGCATTACCTGTTTATGCCATTATTATT
TTGGCTTTTATGAAACCATTTGAACGAATGAACCATGATGTCATGCAGGCAAACGCCATGGTCAGTTCTGCGATTATCGA
GGATATAAACGGTATTGAAACAGTTAAATCTCTAACCAGCGAAGAAACGCGTTATCAAAATATTGACAGAGAATTTGTAG
ATTATCTGGATAAAAGTTTTGCTCTTAACAAATACGAAGCCGTGCAAGGAGCATTAAAACAAGGAGCGCAGCTCATTTTA
AACGTTGCTGTTCTTTGGTATGGCTCACGTTTGGTGATAGCTGGCAGTATTTCTGTCGGGCAGCTCATAACTTATAATAC
GCTTTTGTCCTACTTTACAAGGCCAATGGAGAATATCATCAATCTGCAAACAAAATTACAGTCTGCAAAAGTAGCTAATA
AACGCCTAAATGAAGTTTACTTGGTTTCATCTGAATTTGACGGCGGGCAAATTCTTAATGATAAGCAGTTTCTCAAAGGT
GATATTATTTTTGACGATGTCTCCTATAAGTACGGTTTCGGCCGTGATACGTTAAGCCATGTTAATCTGCGCATTAAAGA
AGGAGAAAAAGTCAGTCTTGTCGGTATTAGTGGTTCTGGTAAGACAACATTAGCTAAGATGATTGTTAATTTTTATACAC
CAAACCAAGGGCAGATTACTCTCGGGGGATATGATTTAAAAACAATTGATAAAAAAGCACTTCGACATTATATTAATTAT
TTGCCGCAGCAATCTTATGTTTTTTCAGGGACTGTTTTAGAAAATTTAACATTGGGTGCTTCTGATAATATGACACAAGA
AGATATTTTTAAAGCCTGTGACATCGCTGAAATTCGTTCTGACATTGAATCTATGCCAATGGCCTACCATACCGAGCTGT
CAGATGGCGCAGGTTTATCGGGCGGTCAAAAGCAGCGTTTAGCACTGGCACGCGCTTTGCTGACACAAGCTCCTGTCTTA
ATTTTAGACGAAGCTACAAGCGGTCTCGATGCCTTAACCGAAAAACGCGTTATCGATAATTTACTGTCCCTCACAGACAG
AACCATTATTTTTGTTGCCCATCGTTTGAGTATTGCTGAACGTTCTGACCGTATTATTGTTATAGACCAAGGGCAGGTTG
CTGAGGAAGGCTCCCACAGACAACTGATACAAGCTCAAGGCTTCTATGCTCATTTATTTCAAAAATAA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(3-139)

ABC transporter (ABC_tran)

(498-647)

ABC transporter transmembrane region (ABC_membrane)

(166-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A372KM53

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

69.944

99.58

0.697
  comA Streptococcus mitis NCTC 12261

66.854

99.58

0.666
  comA Streptococcus mitis SK321

66.292

99.58

0.66
  comA Streptococcus pneumoniae Rx1

66.152

99.58

0.659
  comA Streptococcus pneumoniae D39

66.152

99.58

0.659
  comA Streptococcus pneumoniae R6

66.152

99.58

0.659
  comA Streptococcus pneumoniae TIGR4

65.73

99.58

0.655
  comA Streptococcus gordonii str. Challis substr. CH1

64.747

99.58

0.645

Multiple sequence alignment