Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   DDV21_RS02305 Genome accession   NZ_CP031733
Coordinates   437860..438594 (+) Length   244 a.a.
NCBI ID   WP_116877428.1    Uniprot ID   A0A372KNI0
Organism   Streptococcus chenjunshii strain Z15     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 432860..443594
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DDV21_RS02280 (DDV21_002280) - 432999..433427 (+) 429 WP_116877432.1 Msa family membrane protein -
  DDV21_RS02285 (DDV21_002285) - 433420..434295 (+) 876 WP_116877431.1 ABC transporter ATP-binding protein -
  DDV21_RS02290 (DDV21_002290) - 434300..435070 (+) 771 WP_116877430.1 hypothetical protein -
  DDV21_RS02295 (DDV21_002295) - 435073..436788 (+) 1716 WP_116877520.1 ABC transporter ATP-binding protein -
  DDV21_RS02300 (DDV21_002300) - 437337..437720 (-) 384 WP_116877429.1 hypothetical protein -
  DDV21_RS02305 (DDV21_002305) comE/blpR 437860..438594 (+) 735 WP_116877428.1 response regulator transcription factor Regulator
  DDV21_RS02310 (DDV21_002310) - 439121..439966 (+) 846 WP_116877427.1 GHKL domain-containing protein -
  DDV21_RS02315 (DDV21_002315) - 440489..441583 (-) 1095 WP_241964691.1 alpha/beta hydrolase -
  DDV21_RS02320 (DDV21_002320) - 441662..442084 (-) 423 WP_116877426.1 helix-turn-helix domain-containing protein -
  DDV21_RS02325 (DDV21_002325) rpsF 442424..442714 (+) 291 WP_116877425.1 30S ribosomal protein S6 -
  DDV21_RS02330 (DDV21_002330) ssb 442729..443232 (+) 504 WP_116877424.1 single-stranded DNA-binding protein Machinery gene

Sequence

Protein


Download         Length: 244 a.a.        Molecular weight: 28349.46 Da        Isoelectric Point: 6.5034

>NTDB_id=310821 DDV21_RS02305 WP_116877428.1 437860..438594(+) (comE/blpR) [Streptococcus chenjunshii strain Z15]
MLNIFILEDEYLQQTRLENIIKQSAASKNLKYRHLEIYGKPQQLLDAITEKGNHQLFFLDIEIKGEDQKGMEIAREIRLK
DPNAVIIFVSTHSEFMPVTYKYRVSALDFIDKGLPEEEFQKAVVSVLAHAYEHMGRTIGEDAFIFKNKHSHVQVPFSDIL
FFETSTTVHKVILYTKTGQLEFYGKVSEIATSDERLYQSHRAYVVNPENIVRIDRSNHLVYFEGDESCFVSKLKLKGLIE
RVEK

Nucleotide


Download         Length: 735 bp        

>NTDB_id=310821 DDV21_RS02305 WP_116877428.1 437860..438594(+) (comE/blpR) [Streptococcus chenjunshii strain Z15]
ATGTTAAATATATTTATATTAGAGGATGAGTATTTACAACAAACTCGTTTAGAAAATATCATTAAGCAAAGTGCTGCTTC
AAAAAATTTAAAGTACAGACATTTAGAAATATATGGGAAACCCCAGCAACTGCTAGATGCTATTACTGAGAAAGGGAATC
ATCAGTTATTTTTTCTTGATATTGAAATCAAAGGGGAAGATCAAAAAGGAATGGAGATTGCCCGTGAAATTCGCTTAAAG
GATCCTAATGCTGTTATTATTTTTGTGTCAACACATTCAGAATTTATGCCTGTAACCTATAAATACCGTGTTTCAGCACT
GGATTTTATTGATAAGGGATTGCCCGAAGAAGAATTTCAAAAAGCTGTCGTTTCAGTATTGGCTCATGCTTATGAGCATA
TGGGGCGCACTATTGGAGAAGATGCCTTTATCTTTAAGAATAAGCATTCACATGTTCAGGTTCCCTTTTCGGATATCCTT
TTTTTTGAGACCTCTACAACTGTTCATAAGGTAATCCTCTACACAAAGACAGGACAATTAGAATTTTATGGAAAAGTATC
AGAAATCGCTACATCTGATGAACGACTGTATCAAAGTCACCGAGCCTATGTCGTTAATCCTGAAAATATTGTCCGCATTG
ACCGATCTAATCATTTAGTTTATTTTGAAGGGGATGAGTCTTGTTTTGTCTCCAAGTTAAAATTAAAAGGGCTGATTGAA
AGAGTGGAGAAATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(152-241)

Response regulator receiver domain (Response_reg)

(4-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A372KNI0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

53.975

97.951

0.529
  comE/comE1 Streptococcus equinus JB1

44.77

97.951

0.439
  comE/comE2 Streptococcus equinus JB1

39.506

99.59

0.393
  comE Streptococcus infantis strain Atu-4

35.628

100

0.361

Multiple sequence alignment