Detailed information    

insolico Bioinformatically predicted

Overview


Name   comW   Type   Regulator
Locus tag   ES276_RS00115 Genome accession   NZ_CP038252
Coordinates   23877..24113 (+) Length   78 a.a.
NCBI ID   WP_000939545.1    Uniprot ID   A0A0H2ZMA7
Organism   Streptococcus pneumoniae strain TVO_1901936     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context


Location: 18877..29113
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES276_RS00105 (ES276_00115) - 21934..22779 (+) 846 Protein_15 IS630-like element IS630-Spn1 family transposase -
  ES276_RS00110 (ES276_00120) - 22814..23611 (-) 798 Protein_16 transposase -
  ES276_RS00115 (ES276_00125) comW 23877..24113 (+) 237 WP_000939545.1 sigma(X)-activator ComW Regulator
  ES276_RS00120 (ES276_00130) - 24344..25630 (+) 1287 WP_000205044.1 adenylosuccinate synthase -
  ES276_RS00125 (ES276_00135) tadA 25831..26298 (+) 468 WP_000291875.1 tRNA adenosine(34) deaminase TadA -
  ES276_RS00135 (ES276_00145) - 26485..26928 (+) 444 WP_000701992.1 dUTP diphosphatase -
  ES276_RS00140 (ES276_00150) - 26930..27445 (+) 516 WP_061633556.1 histidine phosphatase family protein -
  ES276_RS00145 (ES276_00155) radA 27459..28820 (+) 1362 WP_074017595.1 DNA repair protein RadA Machinery gene

Sequence


Protein


Download         Length: 78 a.a.        Molecular weight: 9658.13 Da        Isoelectric Point: 6.7051

>NTDB_id=310176 ES276_RS00115 WP_000939545.1 23877..24113(+) (comW) [Streptococcus pneumoniae strain TVO_1901936]
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCRKDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=310176 ES276_RS00115 WP_000939545.1 23877..24113(+) (comW) [Streptococcus pneumoniae strain TVO_1901936]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCGTAAGGATTTTA
TTGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGTTTTATTTCTTGTTGA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A0H2ZMA7

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

100

100

1

  comW Streptococcus pneumoniae D39

100

100

1

  comW Streptococcus pneumoniae R6

100

100

1

  comW Streptococcus pneumoniae TIGR4

100

100

1

  comW Streptococcus mitis SK321

75.641

100

0.756

  comW Streptococcus mitis NCTC 12261

75.325

98.718

0.744


Multiple sequence alignment