Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   CH624_RS04025 Genome accession   NZ_CP031682
Coordinates   767154..768374 (+) Length   406 a.a.
NCBI ID   WP_112109933.1    Uniprot ID   -
Organism   Haemophilus influenzae strain P665-7858     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 762154..773374
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CH624_RS04005 (CH624_04005) corC 763119..764018 (-) 900 WP_005662987.1 CNNM family magnesium/cobalt transport protein CorC -
  CH624_RS04010 (CH624_04010) ampD 764654..765214 (-) 561 WP_005648974.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  CH624_RS04015 (CH624_04015) pilA 765329..765769 (+) 441 WP_112109935.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  CH624_RS04020 (CH624_04020) pilB 765766..767157 (+) 1392 WP_112109934.1 GspE/PulE family protein Machinery gene
  CH624_RS04025 (CH624_04025) pilC 767154..768374 (+) 1221 WP_112109933.1 type II secretion system F family protein Machinery gene
  CH624_RS04030 (CH624_04030) pilD 768371..769063 (+) 693 WP_041175383.1 prepilin peptidase Machinery gene
  CH624_RS04035 (CH624_04035) rho 769117..770379 (-) 1263 WP_005648966.1 transcription termination factor Rho -
  CH624_RS04040 (CH624_04040) metJ 770627..770944 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  CH624_RS04045 (CH624_04045) cueR 770958..771344 (-) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  CH624_RS04050 (CH624_04050) - 771421..771627 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  CH624_RS04055 (CH624_04055) - 771701..771907 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 46297.44 Da        Isoelectric Point: 9.7232

>NTDB_id=309925 CH624_RS04025 WP_112109933.1 767154..768374(+) (pilC) [Haemophilus influenzae strain P665-7858]
MTKKLFYYQASNALNQEQKGSIIADTKQQAHFQLISRGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLSVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFAFSFFLFYYFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSQSLQIMLQAGVPLNQALDSFLPRTQTWQTKKTLVNDMVLDKEVRSILQWVSQG
YAFSNSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFN
MGSVIQ

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=309925 CH624_RS04025 WP_112109933.1 767154..768374(+) (pilC) [Haemophilus influenzae strain P665-7858]
ATGACTAAAAAACTCTTTTATTATCAAGCTAGTAATGCATTAAATCAGGAACAAAAAGGCTCAATTATTGCGGATACAAA
ACAACAAGCACACTTTCAATTAATAAGCCGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAGC
CCAAAAATTCAGAAATTAGTGAATTACTCAATCAATTAGCCACGTTGCTACAGTCCGCTATTCCGTTAAAAAACAGTCTG
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAATGAATGGCTTGAACGACTACTTCAATCTATTGAATCTGGTTT
AGCATTCTCACAAGCCATTGAACAACAAGGGAAATATCTTACTCAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CGGGAAAACTTTCCGTTGTTTGTAAAAAAATAGCCACGCATCGTAGCCAATCTTTAGCATTGCAACGTAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATAGTGCCTCAATT
TGCTGAAATGTACAGTGGCAATAATGCTGAGTTACCAACAATAACCGCAATATTGCTCTCAATATCTAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGCTTTTAGTTTTTTTCTATTTTATTACTTCTATCTAAAACGCCAGACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAGCTTTCACGTTTAGTGAACTTTAG
TCAAAGTTTACAAATTATGTTGCAGGCTGGCGTACCGCTTAATCAGGCACTAGACAGTTTTCTTCCTCGCACACAAACTT
GGCAAACCAAGAAAACGCTTGTAAACGATATGGTATTAGATAAAGAAGTGCGGTCAATTTTGCAATGGGTTTCTCAAGGC
TATGCGTTTTCTAATAGCGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGCTACAAATTGGCGAGCAAAGCGG
AAAACTCGCTTTGATGCTAGAGCATATCGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAA
TGCTAGAACCATTAATGATGGTAATCATCGGAAGCCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAAT
ATGGGTTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)

Type II secretion system (T2SS), protein F (T2SSF)

(266-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

98.03

100

0.98
  pilC Haemophilus influenzae Rd KW20

97.783

100

0.978
  pilC Glaesserella parasuis strain SC1401

37.905

98.768

0.374

Multiple sequence alignment