Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   CH624_RS04030 Genome accession   NZ_CP031682
Coordinates   768371..769063 (+) Length   230 a.a.
NCBI ID   WP_041175383.1    Uniprot ID   -
Organism   Haemophilus influenzae strain P665-7858     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 763371..774063
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CH624_RS04010 (CH624_04010) ampD 764654..765214 (-) 561 WP_005648974.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  CH624_RS04015 (CH624_04015) pilA 765329..765769 (+) 441 WP_112109935.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  CH624_RS04020 (CH624_04020) pilB 765766..767157 (+) 1392 WP_112109934.1 GspE/PulE family protein Machinery gene
  CH624_RS04025 (CH624_04025) pilC 767154..768374 (+) 1221 WP_112109933.1 type II secretion system F family protein Machinery gene
  CH624_RS04030 (CH624_04030) pilD 768371..769063 (+) 693 WP_041175383.1 prepilin peptidase Machinery gene
  CH624_RS04035 (CH624_04035) rho 769117..770379 (-) 1263 WP_005648966.1 transcription termination factor Rho -
  CH624_RS04040 (CH624_04040) metJ 770627..770944 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  CH624_RS04045 (CH624_04045) cueR 770958..771344 (-) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  CH624_RS04050 (CH624_04050) - 771421..771627 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  CH624_RS04055 (CH624_04055) - 771701..771907 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  CH624_RS04060 (CH624_04060) - 771882..774050 (+) 2169 WP_112109932.1 heavy metal translocating P-type ATPase -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26754.82 Da        Isoelectric Point: 9.1329

>NTDB_id=309926 CH624_RS04030 WP_041175383.1 768371..769063(+) (pilD) [Haemophilus influenzae strain P665-7858]
MIYFIMFLLGGILGIALWFYLSGFITHLQQEIYATYVELFPQNRSPFQPHFASIQQKKCGHILRYFLSVGVGFIFLQIAF
KDSIFTVWIGLTLIILWTISYLDWHYQLISTTPCLWLLTLGLFGADNNFSLLTLSESIKSAASFFIVFYAIYWIAKCYYR
KEAFGRGDYWLAMALGSFIRLETLPHFLLLASVLGICFSLIHKKKKEFIPFAPFMNLSAVIIYFVKYYGY

Nucleotide


Download         Length: 693 bp        

>NTDB_id=309926 CH624_RS04030 WP_041175383.1 768371..769063(+) (pilD) [Haemophilus influenzae strain P665-7858]
ATGATTTATTTCATAATGTTTTTATTAGGCGGTATCTTAGGGATCGCATTGTGGTTCTACCTATCTGGTTTTATTACGCA
TTTGCAGCAAGAGATTTATGCGACTTACGTTGAATTATTTCCACAAAACCGTTCTCCATTTCAACCGCACTTTGCCTCTA
TTCAACAAAAAAAGTGCGGTCATATTTTGAGGTATTTTTTAAGTGTTGGAGTTGGATTTATATTTTTACAAATTGCCTTC
AAAGATTCTATTTTTACTGTATGGATCGGACTCACACTTATTATTCTTTGGACAATCAGTTATCTTGATTGGCACTATCA
ACTTATTTCTACGACACCCTGTTTATGGTTACTTACTCTAGGATTATTTGGAGCAGACAATAACTTTTCATTGCTAACGT
TATCTGAAAGCATAAAAAGTGCGGCTAGTTTTTTTATTGTTTTCTACGCAATCTATTGGATTGCAAAATGTTATTACAGA
AAAGAAGCCTTTGGACGGGGAGATTATTGGCTAGCAATGGCATTAGGAAGTTTTATTCGTTTAGAAACCTTACCGCACTT
TTTATTATTAGCTTCAGTGCTTGGAATATGTTTTTCGCTTATTCATAAAAAGAAAAAAGAATTTATACCTTTTGCCCCTT
TTATGAACTTATCAGCTGTCATCATTTATTTCGTCAAATATTACGGATATTAA

Domains

Predicted by InterproScan.

Type IV leader peptidase family (Peptidase_A24)

(92-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Haemophilus influenzae 86-028NP

96.957

100

0.97
  pilD Haemophilus influenzae Rd KW20

94.348

100

0.943

Multiple sequence alignment