Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   CH631_RS03655 Genome accession   NZ_CP031680
Coordinates   724295..725512 (+) Length   405 a.a.
NCBI ID   WP_112102453.1    Uniprot ID   -
Organism   Haemophilus influenzae strain P672-7661     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 719295..730512
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CH631_RS03635 (CH631_03635) corC 720262..721161 (-) 900 WP_116939870.1 CNNM family magnesium/cobalt transport protein CorC -
  CH631_RS03640 (CH631_03640) ampD 721792..722343 (-) 552 WP_071162800.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  CH631_RS03645 (CH631_03645) pilA 722458..722910 (+) 453 WP_116939872.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  CH631_RS03650 (CH631_03650) pilB 722907..724298 (+) 1392 WP_116939874.1 GspE/PulE family protein Machinery gene
  CH631_RS03655 (CH631_03655) pilC 724295..725512 (+) 1218 WP_112102453.1 type II secretion system F family protein Machinery gene
  CH631_RS03660 (CH631_03660) pilD 725509..726201 (+) 693 WP_112102454.1 prepilin peptidase Machinery gene
  CH631_RS03665 (CH631_03665) rho 726255..727517 (-) 1263 WP_112102455.1 transcription termination factor Rho -
  CH631_RS03670 (CH631_03670) metJ 727765..728082 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  CH631_RS03675 (CH631_03675) cueR 728096..728482 (-) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  CH631_RS03680 (CH631_03680) - 728559..728765 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  CH631_RS03685 (CH631_03685) - 728839..729045 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  CH631_RS03690 (CH631_03690) - 729119..729325 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 46070.20 Da        Isoelectric Point: 9.6105

>NTDB_id=309855 CH631_RS03655 WP_112102453.1 724295..725512(+) (pilC) [Haemophilus influenzae strain P672-7661]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLINHGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFALSFVLFYYFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSHSLQIMLQAGIPLNQALDSFLPRTQTWQTKTLVNDIVLDKEVRSILQWVSQGY
AFSDSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFNM
GSVIQ

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=309855 CH631_RS03655 WP_112102453.1 724295..725512(+) (pilC) [Haemophilus influenzae strain P672-7661]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCACACTTTCAGTTAATAAACCACGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAAC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCGACATTGCTACAGTCCGCAATTCCGTTAAAAAACAGCCTG
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAATGAATGGCTTGAACGGCTGCTTCAATCCATTGAATCTGGCTT
AGCATTCTCACAAGCCATTGAACAACAAGGAAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CAGGAAAACTTGCCGTAGTTTGTAAAAAAATAGCCACGCACCGTAGTCAATCTTTGGCTTTACAACGCAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAACAATGCCGAATTACCAACAATAACTGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGCTTTGAGTTTTGTTCTATTTTATTACTTTTATCTAAAACGCCAGACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAACTTTCACGTTTAGTGAACTTTAG
TCACAGTTTACAAATTATGTTACAGGCTGGCATTCCGCTTAATCAAGCACTAGACAGTTTTCTCCCTCGCACACAAACGT
GGCAAACCAAGACGCTTGTAAATGACATCGTATTAGATAAAGAAGTGCGGTCAATTTTACAATGGGTTTCTCAAGGCTAT
GCGTTTTCTGATAGTGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGTTACAAATTGGCGAGCAAAGCGGAAA
ACTCGCTTTGATGCTAGAGCATATTGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAATGC
TAGAACCATTAATGATGGTAATTATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAATATG
GGCTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(266-396)

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

97.044

100

0.973
  pilC Haemophilus influenzae Rd KW20

96.798

100

0.97
  pilC Glaesserella parasuis strain SC1401

38.75

98.765

0.383

Multiple sequence alignment