Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   E3C75_RS03175 Genome accession   NZ_CP038020
Coordinates   596777..597526 (+) Length   249 a.a.
NCBI ID   WP_100273348.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain ATCC 19258     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 591777..602526
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3C75_RS11095 - 592342..592512 (+) 171 WP_167740656.1 hypothetical protein -
  E3C75_RS03150 - 592599..592706 (+) 108 WP_081247985.1 LPXTG cell wall anchor domain-containing protein -
  E3C75_RS03155 - 592793..593533 (-) 741 WP_002949253.1 amino acid ABC transporter ATP-binding protein -
  E3C75_RS03160 - 593533..595083 (-) 1551 WP_011680665.1 ABC transporter substrate-binding protein/permease -
  E3C75_RS03165 - 595286..596140 (+) 855 WP_011680666.1 undecaprenyl-diphosphate phosphatase -
  E3C75_RS03170 - 596192..596500 (-) 309 WP_306496352.1 DUF3021 family protein -
  E3C75_RS03175 mecA 596777..597526 (+) 750 WP_100273348.1 adaptor protein MecA Regulator
  E3C75_RS03180 - 597530..598687 (+) 1158 WP_100262326.1 MraY family glycosyltransferase -
  E3C75_RS03185 sufC 598848..599618 (+) 771 WP_002947634.1 Fe-S cluster assembly ATPase SufC -
  E3C75_RS03190 sufD 599655..600917 (+) 1263 WP_011680669.1 Fe-S cluster assembly protein SufD -
  E3C75_RS03195 - 600971..602203 (+) 1233 WP_046206385.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29116.68 Da        Isoelectric Point: 4.0182

>NTDB_id=309210 E3C75_RS03175 WP_100273348.1 596777..597526(+) (mecA) [Streptococcus thermophilus strain ATCC 19258]
MEMKQISETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEDLDFNDLSDMEDYSGLSPEEFLKALEDNFMDKGDIEAHHKLEELEKTLKEVDETMTDPAKEVAEETIREDYTHYVLAF
SDFDQVVTFAQGLKNVSVEGSELYKLGDVYYMTILLYLADEPDYYANNMYARFLEYANVADRTRPYLQEHATILMEEDAL
PVLQATKWS

Nucleotide


Download         Length: 750 bp        

>NTDB_id=309210 E3C75_RS03175 WP_100273348.1 596777..597526(+) (mecA) [Streptococcus thermophilus strain ATCC 19258]
ATGGAAATGAAACAAATAAGCGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAGCT
GAAAGATTTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTATACTGTCATGGATGAGTTGGACTTACCTGATAACT
TTAAAAATAGTGGGATGTTGAGCTTCCGTGTCACGCCACGAAAGGATCGTGTGGATGTTTTTGTGACTAAATCAGATCTT
AAGGAAGACCTTGATTTCAATGATTTGTCAGATATGGAAGACTATTCAGGACTTTCTCCAGAAGAATTCCTCAAAGCTCT
TGAAGATAACTTTATGGATAAGGGAGATATTGAAGCCCACCATAAGCTCGAAGAGCTTGAAAAGACCTTGAAAGAGGTTG
ATGAGACTATGACAGATCCGGCTAAGGAAGTGGCTGAGGAAACTATTCGTGAAGATTATACTCACTATGTCTTGGCTTTC
TCTGACTTTGATCAAGTAGTGACCTTTGCGCAAGGTTTGAAGAATGTGTCAGTGGAGGGTTCTGAACTTTATAAACTTGG
TGATGTCTACTATATGACTATCCTTCTTTACTTGGCTGATGAGCCTGATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTCCCTATCTACAAGAGCATGCAACAATCTTGATGGAAGAGGACGCCTTA
CCGGTATTACAAGCAACGAAATGGAGCTAG

Domains

Predicted by InterProScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus thermophilus LMD-9

98.394

100

0.984
  mecA Streptococcus thermophilus LMG 18311

97.59

100

0.976
  mecA Streptococcus mutans UA159

59.016

97.992

0.578
  mecA Streptococcus pneumoniae Rx1

46.988

100

0.47
  mecA Streptococcus pneumoniae D39

46.988

100

0.47
  mecA Streptococcus pneumoniae R6

46.988

100

0.47
  mecA Streptococcus pneumoniae TIGR4

46.988

100

0.47

Multiple sequence alignment