Detailed information NTG0307883

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: AB849_RS04115
• Genome accession: NZ_CP036487
• Coordinates: 779410..780438 (-)
• Length: 342 a.a.
• NCBI ID: WP_049720835.1
• Uniprot ID: A0ABS0QJM6
• Organism: Thermoactinomyces vulgaris strain CDF
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 774410..785438

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB849_RS04085 (AB849_004085)	ispF	774886..775365 (-)	480	WP_037996998.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-
AB849_RS04090 (AB849_004090)	ispD	775362..776051 (-)	690	WP_037996996.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
AB849_RS04095 (AB849_004095)	-	776167..777261 (-)	1095	WP_037996994.1	PIN/TRAM domain-containing protein	-
AB849_RS04100 (AB849_004100)	-	777384..777881 (-)	498	WP_231564634.1	CarD family transcriptional regulator	-
AB849_RS04105 (AB849_004105)	-	778154..778549 (+)	396	WP_037996988.1	hypothetical protein	-
AB849_RS04110 (AB849_004110)	pssA	778597..779307 (-)	711	WP_037996982.1	CDP-diacylglycerol--serine O-phosphatidyltransferase	-
AB849_RS04115 (AB849_004115)	disA	779410..780438 (-)	1029	WP_049720835.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
AB849_RS04120 (AB849_004120)	radA/sms	780484..781857 (-)	1374	WP_037996979.1	DNA repair protein RadA	Machinery gene
AB849_RS04125 (AB849_004125)	clpC	782065..784512 (-)	2448	WP_049720819.1	ATP-dependent Clp protease ATP-binding subunit	Regulator

Sequence

Protein

• Length: 342 a.a.
• Molecular weight: 38483.46 Da
• Isoelectric Point: 5.0814

>NTDB_id=307883 AB849_RS04115 WP_049720835.1 779410..780438(-) (disA) [Thermoactinomyces vulgaris strain CDF]
MIAPGTPLREGLDNVLGAKTGALIVIGYDEGVREIVDGGFHIDCPFTPAYLYELAKMDGAIILSNDGKRILYANAQLVPD
SAIPSTETGIRHRTAQRTARQTGKLVVSISQRRNIITLYKGNFRYALKDMGVILTKANQAIQTLEKYKSVLDQTTTNLTA
LEFEELVTLSEVALVLQRVEMVLRIKREIETYIHELGTEGRLVSMQLEELVADTEDEAKLLIEDYCIDPCVSPEVVFQEL
QKLSSDDLLEHANLVRILGYPSSVNIEEEAVLPRGYRILHKIPRLPSHVIYKLVERFENLSRIMVATIDELDEVEGIGSV
RAKMIKEGLKRIQEQVFIDRHI

Nucleotide

• Length: 1029 bp

>NTDB_id=307883 AB849_RS04115 WP_049720835.1 779410..780438(-) (disA) [Thermoactinomyces vulgaris strain CDF]
ATGATCGCTCCGGGAACTCCCTTGAGAGAAGGATTGGACAACGTCCTGGGGGCTAAAACAGGGGCTCTGATCGTGATCGG
CTATGACGAGGGAGTTCGCGAAATTGTGGATGGGGGTTTTCATATCGATTGTCCGTTTACGCCCGCTTATCTTTATGAAT
TGGCCAAGATGGACGGAGCGATTATTCTGAGTAACGACGGGAAAAGGATATTGTATGCAAACGCACAATTGGTTCCTGAT
TCCGCAATCCCTTCCACGGAAACAGGCATCCGTCACCGCACGGCGCAGCGAACGGCTAGGCAGACCGGGAAATTGGTGGT
CTCAATATCCCAGCGCAGAAATATTATCACTTTGTATAAAGGTAACTTTCGTTACGCCCTGAAAGATATGGGAGTGATTT
TGACCAAGGCCAACCAAGCCATCCAAACCTTGGAGAAATACAAATCCGTTTTGGATCAAACCACCACGAACCTGACGGCG
CTGGAGTTTGAAGAGTTGGTCACCTTGAGCGAAGTGGCACTGGTTTTGCAACGGGTAGAAATGGTGCTCAGAATCAAACG
CGAGATCGAAACATATATTCATGAATTGGGAACGGAAGGCCGACTGGTCAGTATGCAATTGGAGGAACTGGTGGCTGACA
CGGAAGATGAAGCGAAGTTGTTGATTGAGGACTATTGCATTGATCCGTGTGTTTCTCCAGAAGTGGTTTTCCAAGAGTTG
CAGAAGTTGTCGTCGGATGATTTGCTGGAACACGCCAACCTGGTGCGGATTTTGGGATATCCATCGTCCGTCAACATTGA
AGAGGAAGCCGTTTTGCCGCGCGGATACCGGATTCTTCATAAAATCCCGCGCCTGCCAAGCCATGTGATTTATAAATTAG
TTGAGCGCTTTGAAAATTTATCGAGAATCATGGTGGCAACCATCGATGAACTGGATGAGGTCGAAGGAATCGGAAGTGTG
CGCGCAAAGATGATCAAAGAAGGATTGAAGCGAATTCAGGAACAAGTATTTATTGACAGACATATATAA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller linker region (DisA-linker) (127-265)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (10-121)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	60.819	100	0.608