Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   L3107_RS09695 Genome accession   NZ_CP031538
Coordinates   1904791..1906938 (+) Length   715 a.a.
NCBI ID   WP_041931940.1    Uniprot ID   A0AAD1K2D7
Organism   Lactococcus cremoris strain 3107     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1876323..1906938 1904791..1906938 within 0


Gene organization within MGE regions


Location: 1876323..1906938
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L3107_RS09535 (L3107_1868) - 1876323..1876907 (-) 585 WP_011835788.1 NUDIX hydrolase -
  L3107_RS09540 (L3107_1869) glmU 1877009..1878385 (-) 1377 WP_021165716.1 bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU -
  L3107_RS09545 (L3107_1870) proC 1878603..1879394 (+) 792 WP_021165717.1 pyrroline-5-carboxylate reductase -
  L3107_RS09550 (L3107_1871) rpsO 1879478..1879747 (-) 270 WP_010906184.1 30S ribosomal protein S15 -
  L3107_RS09555 (L3107_1872) pknB 1879918..1881795 (-) 1878 WP_064305221.1 Stk1 family PASTA domain-containing Ser/Thr kinase -
  L3107_RS09560 (L3107_1873) - 1881795..1882571 (-) 777 WP_011676898.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  L3107_RS09565 (L3107_1874) rsmB 1882694..1883968 (-) 1275 WP_021165718.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  L3107_RS09575 (L3107_1875) - 1884484..1885422 (-) 939 WP_031286545.1 glycosyltransferase family 2 protein -
  L3107_RS09580 - 1885340..1886026 (-) 687 WP_228764429.1 hypothetical protein -
  L3107_RS09585 (L3107_1876) - 1886407..1887297 (+) 891 WP_064305170.1 IS982-like element ISLll1 family transposase -
  L3107_RS09595 (L3107_1878) - 1888160..1889035 (-) 876 WP_116368888.1 IS3 family transposase -
  L3107_RS09605 - 1889110..1889461 (+) 352 Protein_1879 DDE-type integrase/transposase/recombinase -
  L3107_RS09610 (L3107_1879) - 1889530..1890360 (-) 831 WP_015081734.1 AAC(3) family N-acetyltransferase -
  L3107_RS09615 (L3107_1880) - 1890533..1890760 (+) 228 WP_064305222.1 hypothetical protein -
  L3107_RS09620 (L3107_1881) - 1890859..1891539 (+) 681 WP_064305223.1 IS6-like element ISS1S family transposase -
  L3107_RS09625 (L3107_1882) - 1891536..1892573 (-) 1038 WP_021166223.1 RepB family plasmid replication initiator protein -
  L3107_RS09630 (L3107_1883) - 1893245..1894189 (-) 945 WP_021166069.1 toprim domain-containing protein -
  L3107_RS09635 (L3107_1884) - 1894215..1894595 (-) 381 WP_010890681.1 single-stranded DNA-binding protein -
  L3107_RS09645 (L3107_1885) istB 1894994..1895752 (-) 759 WP_003331414.1 IS21-like element IS712 family helper ATPase IstB -
  L3107_RS09650 (L3107_1886) istA 1895764..1896987 (-) 1224 WP_064305106.1 IS21-like element IS712 family transposase -
  L3107_RS09655 (L3107_1887) - 1897237..1897503 (-) 267 WP_010890679.1 hypothetical protein -
  L3107_RS09660 (L3107_1888) - 1897517..1898314 (-) 798 WP_015081778.1 AAA family ATPase -
  L3107_RS09665 (L3107_1889) - 1898458..1899015 (-) 558 WP_015081779.1 recombinase family protein -
  L3107_RS09670 (L3107_1890) - 1899222..1899572 (-) 351 WP_011669087.1 hypothetical protein -
  L3107_RS09675 (L3107_1891) - 1899562..1901028 (-) 1467 WP_116368890.1 Y-family DNA polymerase -
  L3107_RS09680 (L3107_1892) - 1901277..1901912 (+) 636 WP_015081781.1 hypothetical protein -
  L3107_RS09685 (L3107_1893) - 1902017..1903858 (+) 1842 WP_021166190.1 P-loop NTPase fold protein -
  L3107_RS09690 (L3107_1894) - 1904127..1904375 (+) 249 WP_015081783.1 hypothetical protein -
  L3107_RS09695 (L3107_1895) comA 1904791..1906938 (+) 2148 WP_041931940.1 peptide cleavage/export ABC transporter Regulator

Sequence

Protein


Download         Length: 715 a.a.        Molecular weight: 79810.24 Da        Isoelectric Point: 7.5798

>NTDB_id=307365 L3107_RS09695 WP_041931940.1 1904791..1906938(+) (comA) [Lactococcus cremoris strain 3107]
MKFKKKNYTSQVDEMDCGCAALSMILKSYGTEKSLASLRLLAGTTIEGTSALGIKKAAEILEFSVQALRTDASLFEMKNA
PYPFIAHVIKDQKYPHYYVITGANKNSVFIADPDPTIKMTKLSKEAFLSEWTGISLFLSTTPSYHPTKEKASSLLSFIPI
ITRQKKVILNIVIASFIVTLINILGSYYLQSMIDSYIPNALMGTLGIISVGLLLTYIIQQVLEFAKAFLLNVLSQRLAID
VILSYIRHIFQLPMSFFSTRRTGEITSRFSDASSILDAIASTILSLFLDLTIVVMTGLILGLQNMQLFLLVLLAIPLYIV
VIIIFTPLFEKQNHEVMQTNAVLNSSIIEDINGIETIKALASEQERYQKIDYEFASYLKKAFTLQKSEAIQGLIKAIIQL
TLSVTILWFGATLVISQKITLGQLITFNALLSYFTNPITNIINLQTKLQKARVANERLNEVYLVPSEFEEKKTELSLSHF
NLNMSDISYQYGFGRKVLSEIELSIKENEKLTIVGMSGSGKSTLVKLLVNFFQPTSGTITLGGIDLQQFDKHQLRRLINY
LPQQPYIFTGSILDNLLLGANENASQEEILKAVELAEIRADIEQMQLGYQTELSSDASSLSGGQKQRIALARALLSPAKI
LILDEATSNLDMITEKKILKNLLPLDKTIIFIAHRLSVAEMSHRIIVVDQGKVIESGSHVDLLAQNGFYEQLYHN

Nucleotide


Download         Length: 2148 bp        

>NTDB_id=307365 L3107_RS09695 WP_041931940.1 1904791..1906938(+) (comA) [Lactococcus cremoris strain 3107]
ATGAAATTTAAAAAGAAAAATTATACCTCACAAGTAGATGAAATGGACTGTGGCTGTGCTGCCTTATCAATGATTTTAAA
GTCTTATGGCACAGAAAAATCTCTCGCTTCATTGCGCTTACTTGCAGGTACAACAATCGAAGGAACCTCCGCTTTAGGGA
TAAAAAAGGCAGCTGAAATATTAGAGTTTTCAGTTCAGGCCCTAAGAACAGATGCAAGCCTTTTTGAAATGAAAAACGCT
CCTTACCCATTTATTGCTCATGTCATTAAAGACCAAAAATACCCACATTATTATGTGATCACTGGCGCAAATAAAAATTC
GGTATTCATTGCTGATCCTGACCCAACCATTAAAATGACAAAATTATCAAAAGAAGCTTTTTTATCGGAATGGACTGGGA
TTAGTTTATTTCTTTCGACTACACCATCTTATCATCCCACTAAAGAAAAAGCTTCCTCATTATTATCTTTTATCCCAATT
ATCACCCGTCAAAAGAAAGTCATTCTCAATATTGTTATTGCCTCATTCATTGTAACACTGATTAATATTCTAGGCTCTTA
CTACCTCCAGAGCATGATTGACAGCTATATTCCAAATGCCTTAATGGGAACTTTAGGGATTATCTCAGTAGGGCTATTGT
TAACCTATATTATCCAACAGGTCTTAGAATTTGCTAAGGCCTTCTTATTGAACGTTCTTTCTCAAAGATTAGCTATTGAT
GTCATTCTTTCTTATATTAGACACATTTTCCAACTTCCCATGTCTTTCTTTTCGACCCGAAGAACAGGAGAAATTACCAG
TCGGTTTTCCGATGCGAGTTCTATTTTAGATGCTATTGCCTCAACGATTCTTTCGCTCTTTTTAGATTTGACGATTGTCG
TCATGACAGGACTAATTTTAGGCCTTCAAAATATGCAACTCTTTCTTCTCGTTCTTTTGGCAATCCCACTCTATATTGTT
GTTATTATTATTTTTACGCCCCTTTTTGAAAAACAAAACCATGAAGTCATGCAGACCAATGCCGTCTTAAACTCCTCAAT
TATTGAAGATATCAATGGGATTGAAACTATAAAGGCACTTGCCAGTGAACAAGAAAGATATCAAAAAATTGACTACGAAT
TTGCAAGTTATCTAAAAAAGGCTTTCACTTTACAAAAATCAGAAGCTATTCAAGGCTTAATTAAAGCAATTATACAACTA
ACATTGAGTGTCACCATTTTATGGTTTGGTGCCACATTAGTAATAAGTCAAAAAATTACGCTCGGACAATTGATTACTTT
TAATGCCCTGCTTTCTTACTTTACAAATCCAATTACCAATATCATTAACCTTCAAACAAAACTACAAAAGGCAAGGGTAG
CCAATGAACGATTAAATGAGGTCTATCTTGTACCCAGTGAATTTGAGGAAAAGAAAACAGAACTGTCCCTCTCACATTTT
AACTTAAACATGTCCGATATTTCATATCAATATGGTTTTGGCAGAAAAGTCTTATCTGAGATAGAACTCTCTATTAAAGA
AAATGAAAAATTGACTATTGTGGGCATGAGTGGTTCAGGAAAGAGTACCCTTGTTAAATTATTGGTCAACTTCTTTCAAC
CCACTTCTGGCACCATCACTTTAGGTGGAATTGACCTGCAACAGTTTGATAAACACCAACTCCGAAGATTAATCAACTAT
CTTCCCCAACAACCTTATATTTTTACTGGTTCAATTTTAGATAATCTACTTCTAGGAGCTAATGAGAATGCATCACAAGA
AGAGATTCTTAAAGCGGTGGAATTGGCAGAAATCCGTGCAGATATTGAACAAATGCAGTTGGGCTATCAGACCGAACTTT
CAAGTGATGCAAGTAGTCTATCGGGGGGACAAAAACAACGCATTGCTTTAGCTCGTGCGCTCCTTTCCCCTGCCAAAATC
CTCATTTTAGATGAAGCAACCAGTAACCTTGATATGATTACAGAGAAGAAAATATTAAAGAACTTGTTGCCCTTGGATAA
AACCATTATTTTCATTGCTCACCGCCTCTCTGTGGCGGAAATGAGTCATCGAATTATTGTTGTCGATCAAGGAAAAGTGA
TAGAGAGTGGCTCACATGTTGACCTGCTTGCACAAAATGGCTTTTATGAACAACTTTACCATAACTGA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(6-142)

ABC transporter transmembrane region (ABC_membrane)

(169-437)

ABC transporter (ABC_tran)

(498-648)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus gordonii str. Challis substr. CH1

60.924

99.86

0.608
  comA Streptococcus mitis NCTC 12261

59.944

99.86

0.599
  comA Streptococcus mitis SK321

59.664

99.86

0.596
  comA Streptococcus pneumoniae R6

59.524

99.86

0.594
  comA Streptococcus pneumoniae Rx1

59.524

99.86

0.594
  comA Streptococcus pneumoniae D39

59.524

99.86

0.594
  comA Streptococcus pneumoniae TIGR4

59.244

99.86

0.592
  comA/nlmT Streptococcus mutans UA159

57.799

100

0.58

Multiple sequence alignment