Detailed information NTG0307365

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: L3107_RS09695
• Genome accession: NZ_CP031538
• Coordinates: 1904791..1906938 (+)
• Length: 715 a.a.
• NCBI ID: WP_041931940.1
• Uniprot ID: A0AAD1K2D7
• Organism: Lactococcus cremoris strain 3107
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1899791..1911938

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L3107_RS09680 (L3107_1892)	-	1901277..1901912 (+)	636	WP_015081781.1	hypothetical protein	-
L3107_RS09685 (L3107_1893)	-	1902017..1903858 (+)	1842	WP_021166190.1	P-loop NTPase fold protein	-
L3107_RS09690 (L3107_1894)	-	1904127..1904375 (+)	249	WP_015081783.1	hypothetical protein	-
L3107_RS09695 (L3107_1895)	comA	1904791..1906938 (+)	2148	WP_041931940.1	peptide cleavage/export ABC transporter	Regulator
L3107_RS09700 (L3107_1896)	-	1906953..1908377 (+)	1425	WP_081146283.1	HlyD family secretion protein	-
L3107_RS09705 (L3107_1897)	-	1908451..1908678 (+)	228	WP_015081786.1	lactococcin family bacteriocin	-
L3107_RS09710 (L3107_1898)	-	1908693..1908989 (+)	297	WP_064305224.1	bacteriocin immunity protein	-
L3107_RS09715 (L3107_1899)	-	1909264..1909470 (+)	207	WP_015081788.1	lactococcin family bacteriocin	-
L3107_RS09720 (L3107_1900)	lciB	1909497..1909772 (+)	276	WP_032488552.1	lactococcin-B immunity protein	-
L3107_RS09725	-	1910252..1910384 (+)	133	Protein_1902	IS3 family transposase	-
L3107_RS09730 (L3107_1901)	-	1910553..1910717 (+)	165	WP_021166195.1	lactococcin family bacteriocin	-
L3107_RS09735 (L3107_1902)	-	1910920..1911372 (+)	453	WP_015081789.1	hypothetical protein	-

Sequence

Protein

• Length: 715 a.a.
• Molecular weight: 79810.24 Da
• Isoelectric Point: 7.5798

>NTDB_id=307365 L3107_RS09695 WP_041931940.1 1904791..1906938(+) (comA) [Lactococcus cremoris strain 3107]
MKFKKKNYTSQVDEMDCGCAALSMILKSYGTEKSLASLRLLAGTTIEGTSALGIKKAAEILEFSVQALRTDASLFEMKNA
PYPFIAHVIKDQKYPHYYVITGANKNSVFIADPDPTIKMTKLSKEAFLSEWTGISLFLSTTPSYHPTKEKASSLLSFIPI
ITRQKKVILNIVIASFIVTLINILGSYYLQSMIDSYIPNALMGTLGIISVGLLLTYIIQQVLEFAKAFLLNVLSQRLAID
VILSYIRHIFQLPMSFFSTRRTGEITSRFSDASSILDAIASTILSLFLDLTIVVMTGLILGLQNMQLFLLVLLAIPLYIV
VIIIFTPLFEKQNHEVMQTNAVLNSSIIEDINGIETIKALASEQERYQKIDYEFASYLKKAFTLQKSEAIQGLIKAIIQL
TLSVTILWFGATLVISQKITLGQLITFNALLSYFTNPITNIINLQTKLQKARVANERLNEVYLVPSEFEEKKTELSLSHF
NLNMSDISYQYGFGRKVLSEIELSIKENEKLTIVGMSGSGKSTLVKLLVNFFQPTSGTITLGGIDLQQFDKHQLRRLINY
LPQQPYIFTGSILDNLLLGANENASQEEILKAVELAEIRADIEQMQLGYQTELSSDASSLSGGQKQRIALARALLSPAKI
LILDEATSNLDMITEKKILKNLLPLDKTIIFIAHRLSVAEMSHRIIVVDQGKVIESGSHVDLLAQNGFYEQLYHN

Nucleotide

• Length: 2148 bp

>NTDB_id=307365 L3107_RS09695 WP_041931940.1 1904791..1906938(+) (comA) [Lactococcus cremoris strain 3107]
ATGAAATTTAAAAAGAAAAATTATACCTCACAAGTAGATGAAATGGACTGTGGCTGTGCTGCCTTATCAATGATTTTAAA
GTCTTATGGCACAGAAAAATCTCTCGCTTCATTGCGCTTACTTGCAGGTACAACAATCGAAGGAACCTCCGCTTTAGGGA
TAAAAAAGGCAGCTGAAATATTAGAGTTTTCAGTTCAGGCCCTAAGAACAGATGCAAGCCTTTTTGAAATGAAAAACGCT
CCTTACCCATTTATTGCTCATGTCATTAAAGACCAAAAATACCCACATTATTATGTGATCACTGGCGCAAATAAAAATTC
GGTATTCATTGCTGATCCTGACCCAACCATTAAAATGACAAAATTATCAAAAGAAGCTTTTTTATCGGAATGGACTGGGA
TTAGTTTATTTCTTTCGACTACACCATCTTATCATCCCACTAAAGAAAAAGCTTCCTCATTATTATCTTTTATCCCAATT
ATCACCCGTCAAAAGAAAGTCATTCTCAATATTGTTATTGCCTCATTCATTGTAACACTGATTAATATTCTAGGCTCTTA
CTACCTCCAGAGCATGATTGACAGCTATATTCCAAATGCCTTAATGGGAACTTTAGGGATTATCTCAGTAGGGCTATTGT
TAACCTATATTATCCAACAGGTCTTAGAATTTGCTAAGGCCTTCTTATTGAACGTTCTTTCTCAAAGATTAGCTATTGAT
GTCATTCTTTCTTATATTAGACACATTTTCCAACTTCCCATGTCTTTCTTTTCGACCCGAAGAACAGGAGAAATTACCAG
TCGGTTTTCCGATGCGAGTTCTATTTTAGATGCTATTGCCTCAACGATTCTTTCGCTCTTTTTAGATTTGACGATTGTCG
TCATGACAGGACTAATTTTAGGCCTTCAAAATATGCAACTCTTTCTTCTCGTTCTTTTGGCAATCCCACTCTATATTGTT
GTTATTATTATTTTTACGCCCCTTTTTGAAAAACAAAACCATGAAGTCATGCAGACCAATGCCGTCTTAAACTCCTCAAT
TATTGAAGATATCAATGGGATTGAAACTATAAAGGCACTTGCCAGTGAACAAGAAAGATATCAAAAAATTGACTACGAAT
TTGCAAGTTATCTAAAAAAGGCTTTCACTTTACAAAAATCAGAAGCTATTCAAGGCTTAATTAAAGCAATTATACAACTA
ACATTGAGTGTCACCATTTTATGGTTTGGTGCCACATTAGTAATAAGTCAAAAAATTACGCTCGGACAATTGATTACTTT
TAATGCCCTGCTTTCTTACTTTACAAATCCAATTACCAATATCATTAACCTTCAAACAAAACTACAAAAGGCAAGGGTAG
CCAATGAACGATTAAATGAGGTCTATCTTGTACCCAGTGAATTTGAGGAAAAGAAAACAGAACTGTCCCTCTCACATTTT
AACTTAAACATGTCCGATATTTCATATCAATATGGTTTTGGCAGAAAAGTCTTATCTGAGATAGAACTCTCTATTAAAGA
AAATGAAAAATTGACTATTGTGGGCATGAGTGGTTCAGGAAAGAGTACCCTTGTTAAATTATTGGTCAACTTCTTTCAAC
CCACTTCTGGCACCATCACTTTAGGTGGAATTGACCTGCAACAGTTTGATAAACACCAACTCCGAAGATTAATCAACTAT
CTTCCCCAACAACCTTATATTTTTACTGGTTCAATTTTAGATAATCTACTTCTAGGAGCTAATGAGAATGCATCACAAGA
AGAGATTCTTAAAGCGGTGGAATTGGCAGAAATCCGTGCAGATATTGAACAAATGCAGTTGGGCTATCAGACCGAACTTT
CAAGTGATGCAAGTAGTCTATCGGGGGGACAAAAACAACGCATTGCTTTAGCTCGTGCGCTCCTTTCCCCTGCCAAAATC
CTCATTTTAGATGAAGCAACCAGTAACCTTGATATGATTACAGAGAAGAAAATATTAAAGAACTTGTTGCCCTTGGATAA
AACCATTATTTTCATTGCTCACCGCCTCTCTGTGGCGGAAATGAGTCATCGAATTATTGTTGTCGATCAAGGAAAAGTGA
TAGAGAGTGGCTCACATGTTGACCTGCTTGCACAAAATGGCTTTTATGAACAACTTTACCATAACTGA

Domains

Predicted by InterProScan.

• Peptidase C39 family (Peptidase_C39) (6-142)

• ABC transporter transmembrane region (ABC_membrane) (169-437)

• ABC transporter (ABC_tran) (498-648)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus gordonii str. Challis substr. CH1	60.924	99.86	0.608
comA	Streptococcus mitis NCTC 12261	59.944	99.86	0.599
comA	Streptococcus mitis SK321	59.664	99.86	0.596
comA	Streptococcus pneumoniae R6	59.524	99.86	0.594
comA	Streptococcus pneumoniae Rx1	59.524	99.86	0.594
comA	Streptococcus pneumoniae D39	59.524	99.86	0.594
comA	Streptococcus pneumoniae TIGR4	59.244	99.86	0.592
comA/nlmT	Streptococcus mutans UA159	57.799	100	0.58