Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   DXX82_RS03715 Genome accession   NZ_CP031477
Coordinates   772769..774151 (-) Length   460 a.a.
NCBI ID   WP_115911560.1    Uniprot ID   -
Organism   Haemophilus parainfluenzae strain M27794     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 767769..779151
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DXX82_RS03690 - 768060..768929 (-) 870 WP_115911555.1 DUF535 family protein -
  DXX82_RS03695 yihA 769043..769657 (+) 615 WP_115911556.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  DXX82_RS03700 comM 769787..771316 (+) 1530 WP_115911558.1 YifB family Mg chelatase-like AAA ATPase Machinery gene
  DXX82_RS03705 nfuA 771360..771944 (-) 585 WP_005694707.1 Fe-S biogenesis protein NfuA -
  DXX82_RS03710 - 772060..772749 (-) 690 WP_005697373.1 ComF family protein -
  DXX82_RS03715 comE 772769..774151 (-) 1383 WP_115911560.1 type IV pilus secretin PilQ Machinery gene
  DXX82_RS03720 - 774153..774536 (-) 384 WP_115911562.1 pilus assembly protein PilP -
  DXX82_RS03725 - 774536..775078 (-) 543 WP_115911564.1 competence protein ComC -
  DXX82_RS03730 - 775075..775587 (-) 513 WP_115911566.1 competence protein ComB -
  DXX82_RS03735 - 775574..776422 (-) 849 WP_115911568.1 pilus assembly protein PilM -
  DXX82_RS03740 - 776522..779134 (+) 2613 WP_111304846.1 penicillin-binding protein 1A -

Sequence

Protein


Download         Length: 460 a.a.        Molecular weight: 51020.64 Da        Isoelectric Point: 7.2238

>NTDB_id=307125 DXX82_RS03715 WP_115911560.1 772769..774151(-) (comE) [Haemophilus parainfluenzae strain M27794]
MIKQKIKTKCGQFLMCFLILWTTYSAAENRVFSLRLKQAPMVATLQQLALEQNANLMIDDELEGTLSLQLDNVDFDRLLR
SVAKIKGLSFYQENNIYYLGKPSQHEQYAEKMAEPMAISGESLPSETPLVSATVKLHFAKASDVMKSLTTGSGSLLSPSG
TITFDDRSNVLLIQDDARSVKNIKKLIAELDKPIEQIVIEARIVTITDESLKELGVRWGIFNPTEAAHRVSGSLDANGFS
NISNNLNVNFATTVTPAGSLALQVAKINGRLLDLELTALERENNVEIIASPRLLTTNKKSASIKQGTEIPYVVTNGKNDT
QSVEFREAVLGLEVTPHISKDNNILLDLLVSQNSPGNRVAYGQNEVVSIDKQEINTQVFAKDGETIVLGGVFHDTITKGV
DKVPLLGDIPGIKHLFSKESERHQKRELVIFVTPHILKQGERMEMAKKEKHFKQIEKVKK

Nucleotide


Download         Length: 1383 bp        

>NTDB_id=307125 DXX82_RS03715 WP_115911560.1 772769..774151(-) (comE) [Haemophilus parainfluenzae strain M27794]
ATGATAAAGCAGAAAATAAAAACAAAGTGCGGTCAGTTTTTAATGTGTTTTTTGATCCTATGGACAACTTACTCAGCGGC
AGAAAATCGCGTATTTTCACTTCGCTTAAAGCAAGCTCCCATGGTGGCGACACTCCAACAACTTGCTCTTGAGCAAAATG
CTAATTTAATGATTGATGATGAGCTAGAAGGAACGCTTTCATTACAATTAGATAACGTAGATTTTGATCGTTTATTGCGT
TCTGTCGCAAAAATCAAAGGGCTCTCTTTTTATCAAGAAAATAATATTTATTATTTAGGTAAGCCTTCTCAACATGAACA
ATATGCAGAGAAAATGGCAGAACCGATGGCGATTAGCGGAGAAAGTTTGCCTAGTGAAACACCACTTGTGAGTGCAACGG
TTAAACTGCATTTTGCCAAAGCTTCTGATGTGATGAAATCGTTAACAACAGGGAGTGGTTCTTTGCTTTCACCTAGCGGC
ACAATTACATTTGATGACCGAAGCAATGTGTTACTGATTCAGGATGATGCACGTTCTGTCAAAAATATTAAAAAATTGAT
TGCAGAGCTGGATAAACCCATTGAGCAAATTGTCATTGAAGCACGTATTGTGACGATTACTGATGAAAGCCTGAAAGAGT
TAGGTGTACGTTGGGGCATTTTTAATCCTACTGAGGCAGCCCATCGAGTGAGTGGCAGTTTAGATGCGAATGGGTTTAGC
AATATCAGTAATAATTTAAATGTAAATTTTGCGACAACGGTCACGCCAGCTGGCTCATTAGCACTTCAAGTAGCCAAAAT
TAATGGTCGATTATTAGACCTAGAATTGACCGCACTTGAACGTGAAAATAACGTAGAAATTATAGCGAGTCCTCGCTTAC
TCACGACCAACAAAAAAAGCGCAAGCATCAAACAAGGGACAGAAATTCCTTATGTGGTGACGAATGGTAAAAATGACACG
CAGTCAGTGGAGTTTCGTGAAGCCGTGTTAGGATTGGAGGTCACGCCGCATATTTCGAAGGATAATAATATTCTATTGGA
TTTATTAGTGAGTCAAAATTCCCCGGGAAATCGCGTGGCTTACGGGCAAAATGAAGTGGTATCCATTGATAAACAAGAAA
TTAATACGCAAGTGTTTGCCAAAGATGGGGAAACGATTGTATTGGGTGGTGTATTTCACGATACGATCACGAAAGGTGTC
GATAAAGTACCATTATTGGGCGATATTCCAGGTATTAAGCACTTATTTAGTAAGGAAAGTGAACGTCATCAAAAGCGAGA
GCTTGTGATTTTTGTGACACCTCATATTTTAAAACAAGGTGAAAGAATGGAAATGGCTAAGAAAGAAAAACATTTCAAGC
AAATTGAAAAAGTGAAAAAATAA

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(278-438)

Bacterial type II/III secretion system short domain (Secretin_N)

(132-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae Rd KW20

73.274

97.609

0.715
  comE Haemophilus influenzae 86-028NP

72.383

97.609

0.707
  comE Glaesserella parasuis strain SC1401

54.137

91.957

0.498
  pilQ Vibrio campbellii strain DS40M4

41.667

93.913

0.391
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

42.217

92.174

0.389
  pilQ Vibrio cholerae strain A1552

42.217

92.174

0.389

Multiple sequence alignment