Detailed information NTG0030652

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: SDEG_RS02575
• Genome accession: NC_012891
• Coordinates: 490276..492429 (-)
• Length: 717 a.a.
• NCBI ID: WP_003062135.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis GGS_124
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 485276..497429

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SDEG_RS02545 (SDEG_0513)	-	485418..485657 (+)	240	WP_012766647.1	Blp family class II bacteriocin	-
SDEG_RS02550	-	485671..485856 (+)	186	WP_003054392.1	hypothetical protein	-
SDEG_RS02560 (SDEG_0515)	comE/blpR	486540..487289 (+)	750	WP_012766649.1	response regulator transcription factor	Regulator
SDEG_RS02565 (SDEG_0516)	-	487290..488624 (+)	1335	WP_012766650.1	sensor histidine kinase	-
SDEG_RS10710 (SDEG_0517)	-	488685..488810 (-)	126	WP_011017462.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
SDEG_RS02570 (SDEG_0518)	-	488901..490265 (-)	1365	WP_012766651.1	bacteriocin secretion accessory protein	-
SDEG_RS02575 (SDEG_0519)	comA/nlmT	490276..492429 (-)	2154	WP_003062135.1	peptide cleavage/export ABC transporter	Regulator
SDEG_RS02580 (SDEG_0520)	-	492830..493852 (+)	1023	WP_171841606.1	IS30 family transposase	-
SDEG_RS02585	-	493902..494120 (+)	219	WP_269146493.1	Blp family class II bacteriocin	-
SDEG_RS02590 (SDEG_0521)	-	494133..494333 (+)	201	WP_003060803.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
SDEG_RS02600 (SDEG_0522)	-	494628..494822 (+)	195	WP_012766652.1	hypothetical protein	-
SDEG_RS02610 (SDEG_0524)	-	495348..495758 (+)	411	WP_012766654.1	hypothetical protein	-
SDEG_RS11250	-	496005..496252 (+)	248	Protein_473	hypothetical protein	-
SDEG_RS10720 (SDEG_0526)	-	496274..496504 (+)	231	WP_012766656.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80558.51 Da
• Isoelectric Point: 7.0109

>NTDB_id=30652 SDEG_RS02575 WP_003062135.1 490276..492429(-) (comA/nlmT) [Streptococcus dysgalactiae subsp. equisimilis GGS_124]
MISYRKTFVAQIDARDCGVAALASIAKYYGSDYSLAHLRELAKTNKEGTTALGIVKAAKLMGFETRAIQADMTLFDIEDV
PYPFIVHVNKEGKFQHYYVVYQNKKNYLIIGDPDPTVKVTKMTKERFTSEWTGVAIFLAPEPSYKPHKDKKNGLISFLPL
IFKQRSLIFYIILASLLVTLINIVGSYYLQGILDDYIPNQLKSTLGIISIGLIITYILQQMMSFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEIISRFTDANAIIDALASTILSLFLDVSILTIVGTVLLVQNTNLFLLSLVSVPLYIV
IIFIFMHPFEKMNNDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQKIDSEFVDYLDKSFKLSKYSILQSSLKQGAQL
ILNVIVLWFGAKLVMGGKISVGQLITFNTLLSYFTNPLENIINLQTKLQSAKVANNRLNEVYLVDSEFQEAGTLVNQELL
HGDIQFEELSYKYGFGRDTLSNINLTIKQGDKVSLVGISGSGKTTLAKMIVNFFEPYNGRITINHNDLKMIDKKSLRQHI
NYLPQQAYIFNGSILENLTLGANDCTSHEDILRACEVAEIRQDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKAP
VLILDEATSGLDVLTEKRVIDNLLAMTDKTIIFVAHRLSISARTNQVIVLDEGKIIEIGSHQELMTKQGFYHHLFSS

Nucleotide

• Length: 2154 bp

>NTDB_id=30652 SDEG_RS02575 WP_003062135.1 490276..492429(-) (comA/nlmT) [Streptococcus dysgalactiae subsp. equisimilis GGS_124]
ATGATATCCTATCGAAAAACATTTGTTGCTCAGATTGATGCTAGAGACTGTGGTGTGGCTGCTCTTGCTTCCATCGCTAA
ATATTACGGTTCAGACTACTCTTTAGCTCATTTAAGAGAGTTAGCTAAAACAAATAAAGAGGGAACAACAGCGCTTGGCA
TCGTCAAAGCTGCCAAATTAATGGGATTTGAAACAAGAGCTATTCAAGCAGACATGACCCTCTTTGATATAGAAGATGTC
CCTTATCCTTTTATTGTTCATGTTAATAAAGAAGGTAAATTCCAACACTACTATGTCGTCTATCAAAACAAAAAAAATTA
TCTGATAATCGGCGACCCTGACCCGACAGTAAAAGTCACTAAGATGACAAAGGAGCGATTTACTTCTGAATGGACGGGTG
TCGCTATTTTTCTAGCACCCGAGCCCAGCTACAAGCCTCATAAGGACAAAAAGAACGGTCTAATAAGCTTTTTACCTCTC
ATTTTTAAACAGCGATCTCTGATTTTCTATATCATATTAGCTAGCCTACTCGTTACTCTGATTAATATTGTAGGTTCTTA
TTACCTACAAGGTATATTAGATGACTATATTCCAAATCAACTGAAATCAACACTCGGTATTATTTCAATTGGTCTTATCA
TTACCTATATCCTCCAACAGATGATGAGTTTTTCGCGAGATTATCTCCTGACTGTACTGAGTCAGCGATTAAGCATTGAT
GTTATTTTATCCTATATTCGTCATATTTTTGAGCTTCCCATGTCTTTTTTTGCAACTCGCAGAACAGGAGAAATCATCTC
ACGTTTTACAGATGCTAATGCTATTATTGATGCACTCGCTTCTACTATTTTGTCTCTTTTTCTTGATGTCAGTATTTTAA
CTATCGTAGGGACAGTTCTGTTAGTGCAAAATACCAATCTTTTTCTTCTATCTCTGGTTTCAGTCCCTCTATATATTGTT
ATTATCTTTATATTTATGCACCCATTTGAAAAGATGAATAATGATGTCATGCAGAGTAACTCTATGGTTAGCTCAGCCAT
TATCGAAGATATCAATGGCATTGAAACTATTAAATCACTGACCAGTGAAGAAAATCGTTATCAGAAAATTGATAGTGAAT
TTGTGGACTATCTGGATAAATCTTTCAAGTTAAGTAAGTACTCTATTTTACAAAGCAGTCTCAAACAAGGGGCGCAACTA
ATCCTTAACGTGATAGTCTTATGGTTTGGGGCCAAATTAGTTATGGGAGGAAAAATTTCTGTTGGTCAGTTGATTACGTT
TAATACTCTCTTATCTTATTTTACCAATCCTTTAGAAAATATCATTAATCTTCAAACTAAACTGCAATCAGCCAAGGTAG
CTAATAATCGTCTCAATGAAGTTTACCTAGTCGATTCTGAGTTTCAAGAGGCTGGGACATTAGTCAATCAAGAATTATTA
CACGGAGACATTCAATTTGAAGAGTTATCCTATAAATATGGCTTTGGACGCGATACTCTATCAAATATTAATCTCACTAT
TAAGCAAGGGGACAAAGTTAGCCTTGTTGGTATTAGTGGATCTGGTAAAACGACTCTAGCTAAAATGATTGTTAATTTTT
TTGAGCCTTATAACGGCCGAATTACCATTAATCATAATGACTTAAAAATGATTGATAAAAAAAGTCTTCGCCAACATATT
AATTATCTCCCCCAACAAGCCTATATTTTTAATGGTTCTATTTTAGAAAATTTAACCTTAGGTGCTAATGACTGTACTAG
TCATGAAGATATTCTAAGAGCTTGTGAGGTTGCAGAAATTCGACAAGATATTGAACAAATGCCTATGGGCTATCAAACAG
AGCTTTCTGATGGTGCCGGACTCTCAGGAGGCCAAAAGCAACGAATTGCACTTGCCAGAGCTCTCCTAACCAAGGCGCCT
GTGCTTATTCTAGATGAGGCTACAAGCGGTCTTGACGTACTAACTGAAAAGAGGGTTATTGATAATCTTTTGGCTATGAC
GGATAAAACTATTATTTTCGTAGCTCATCGTCTCAGCATTTCAGCGCGGACCAATCAAGTCATTGTGCTTGATGAGGGTA
AAATTATTGAAATAGGATCTCATCAAGAATTAATGACTAAACAAGGTTTCTATCATCATTTATTTAGTAGTTAA

Domains

Predicted by InterProScan.

• ABC transporter transmembrane region (ABC_membrane) (168-438)

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter (ABC_tran) (500-649)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	72.867	99.721	0.727
comA	Streptococcus mitis NCTC 12261	67.647	99.582	0.674
comA	Streptococcus mitis SK321	67.227	99.582	0.669
comA	Streptococcus pneumoniae Rx1	67.227	99.582	0.669
comA	Streptococcus pneumoniae D39	67.227	99.582	0.669
comA	Streptococcus pneumoniae R6	67.227	99.582	0.669
comA	Streptococcus pneumoniae TIGR4	66.947	99.582	0.667
comA	Streptococcus gordonii str. Challis substr. CH1	66.017	100	0.661