Detailed information
Bioinformatically predicted
Overview
| Name | pilU | Type | Machinery gene |
| Locus tag | DLE02_RS04815 | Genome accession | NZ_CP031383 |
| Coordinates | 992738..993856 (-) | Length | 372 a.a. |
| NCBI ID | WP_000347040.1 | Uniprot ID | A0A809JLP7 |
| Organism | Acinetobacter baumannii strain LUH 6011 | ||
| Function | mediate the depolymerization of the type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 956362..1022272 | 992738..993856 | within | 0 |
Gene organization within MGE regions
Location: 956362..1022272
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| DLE02_RS04635 (DLE02_00902) | - | 956763..957323 (-) | 561 | WP_001048150.1 | hypothetical protein | - |
| DLE02_RS04640 (DLE02_00903) | - | 957414..958274 (-) | 861 | WP_000838098.1 | pirin family protein | - |
| DLE02_RS04645 (DLE02_00904) | hemJ | 958445..958897 (-) | 453 | WP_000339889.1 | protoporphyrinogen oxidase HemJ | - |
| DLE02_RS04650 (DLE02_00905) | - | 958916..960145 (-) | 1230 | WP_004748109.1 | beta-ketoacyl-ACP synthase II | - |
| DLE02_RS04655 (DLE02_00906) | - | 960442..961767 (+) | 1326 | WP_004748107.1 | EcsC family protein | - |
| DLE02_RS04660 (DLE02_00907) | rpsL | 961968..962342 (+) | 375 | WP_000246374.1 | 30S ribosomal protein S12 | - |
| DLE02_RS04665 (DLE02_00908) | rpsG | 962502..962972 (+) | 471 | WP_001138055.1 | 30S ribosomal protein S7 | - |
| DLE02_RS04670 (DLE02_00909) | fusA | 963152..965290 (+) | 2139 | WP_004748104.1 | elongation factor G | - |
| DLE02_RS04675 (DLE02_00910) | tuf | 965385..966575 (+) | 1191 | WP_001029610.1 | elongation factor Tu | - |
| DLE02_RS04680 (DLE02_00911) | - | 966779..967660 (+) | 882 | WP_000992305.1 | metal-dependent hydrolase | - |
| DLE02_RS04685 (DLE02_00912) | - | 967897..968772 (+) | 876 | WP_000992291.1 | metal-dependent hydrolase | - |
| DLE02_RS04690 (DLE02_00913) | rimI | 968881..969336 (+) | 456 | WP_000621543.1 | ribosomal protein S18-alanine N-acetyltransferase | - |
| DLE02_RS04695 (DLE02_00914) | - | 969381..970196 (-) | 816 | WP_000844343.1 | arginyltransferase | - |
| DLE02_RS04700 (DLE02_00915) | aat | 970215..970946 (-) | 732 | WP_000854785.1 | leucyl/phenylalanyl-tRNA--protein transferase | - |
| DLE02_RS04705 (DLE02_00916) | trxB | 971066..972013 (-) | 948 | WP_001276144.1 | thioredoxin-disulfide reductase | - |
| DLE02_RS04710 (DLE02_00917) | - | 972283..975315 (+) | 3033 | WP_000127823.1 | DNA translocase FtsK | - |
| DLE02_RS04715 (DLE02_00918) | rhtC | 975465..976085 (+) | 621 | WP_000959259.1 | threonine export protein RhtC | - |
| DLE02_RS04720 (DLE02_00919) | - | 976141..976671 (-) | 531 | WP_031969348.1 | tyrosyl-tRNA synthetase | - |
| DLE02_RS04725 (DLE02_00920) | - | 977044..977331 (-) | 288 | WP_001218560.1 | PA4642 family protein | - |
| DLE02_RS04730 (DLE02_00921) | minE | 977415..977687 (-) | 273 | WP_000896934.1 | cell division topological specificity factor MinE | - |
| DLE02_RS04735 (DLE02_00922) | minD | 977690..978502 (-) | 813 | WP_001074362.1 | septum site-determining protein MinD | - |
| DLE02_RS04740 (DLE02_00923) | minC | 978573..979295 (-) | 723 | WP_000763677.1 | septum site-determining protein MinC | - |
| DLE02_RS04745 (DLE02_00924) | - | 979417..980463 (-) | 1047 | WP_001181639.1 | hypothetical protein | - |
| DLE02_RS04750 (DLE02_00925) | - | 980480..981406 (-) | 927 | WP_000100965.1 | acyltransferase | - |
| DLE02_RS04755 (DLE02_00926) | - | 981651..982304 (+) | 654 | WP_001202415.1 | OmpA family protein | - |
| DLE02_RS04760 (DLE02_00928) | rep | 982498..984537 (+) | 2040 | WP_000093035.1 | DNA helicase Rep | - |
| DLE02_RS04765 (DLE02_00929) | dut | 984562..985014 (+) | 453 | WP_000868152.1 | dUTP diphosphatase | - |
| DLE02_RS04770 (DLE02_00930) | - | 985214..986632 (+) | 1419 | WP_001102845.1 | phosphomannomutase/phosphoglucomutase | - |
| DLE02_RS04775 (DLE02_00931) | argB | 986647..987555 (+) | 909 | WP_001135419.1 | acetylglutamate kinase | - |
| DLE02_RS04780 (DLE02_00932) | - | 987676..988458 (+) | 783 | WP_000890283.1 | GNAT family N-acetyltransferase | - |
| DLE02_RS04785 (DLE02_00933) | - | 988567..989415 (+) | 849 | WP_000336548.1 | class II glutamine amidotransferase | - |
| DLE02_RS04790 (DLE02_00934) | - | 989668..990123 (+) | 456 | WP_000782976.1 | bacteriohemerythrin | - |
| DLE02_RS04795 (DLE02_00935) | - | 990276..991343 (+) | 1068 | WP_004748097.1 | hypothetical protein | - |
| DLE02_RS04800 (DLE02_00936) | - | 991343..991666 (+) | 324 | WP_000442590.1 | RnfH family protein | - |
| DLE02_RS04805 (DLE02_00937) | - | 991721..992119 (-) | 399 | WP_001170994.1 | outer membrane protein assembly factor BamE | - |
| DLE02_RS04810 (DLE02_00938) | fur | 992231..992668 (+) | 438 | WP_001122847.1 | ferric iron uptake transcriptional regulator | - |
| DLE02_RS04815 (DLE02_00939) | pilU | 992738..993856 (-) | 1119 | WP_000347040.1 | PilT/PilU family type 4a pilus ATPase | Machinery gene |
| DLE02_RS04820 (DLE02_00940) | pilT | 993884..994921 (-) | 1038 | WP_000355489.1 | type IV pilus twitching motility protein PilT | Machinery gene |
| DLE02_RS04825 (DLE02_00941) | - | 995048..995740 (+) | 693 | WP_004748094.1 | YggS family pyridoxal phosphate-dependent enzyme | - |
| DLE02_RS04830 (DLE02_00942) | - | 995942..999538 (-) | 3597 | WP_004748092.1 | SbcC/MukB-like Walker B domain-containing protein | - |
| DLE02_RS04835 (DLE02_00943) | - | 999548..1000816 (-) | 1269 | WP_004748090.1 | exonuclease SbcCD subunit D | - |
| DLE02_RS04840 (DLE02_00944) | - | 1000981..1001454 (+) | 474 | WP_000974355.1 | OsmC family protein | - |
| DLE02_RS04845 (DLE02_00945) | - | 1001522..1001899 (-) | 378 | WP_001059437.1 | VOC family protein | - |
| DLE02_RS04850 (DLE02_00946) | - | 1002279..1002731 (+) | 453 | WP_000164151.1 | ABZJ_00895 family protein | - |
| DLE02_RS04855 (DLE02_00947) | - | 1002819..1003724 (+) | 906 | WP_046693190.1 | TIGR01777 family oxidoreductase | - |
| DLE02_RS04860 (DLE02_00948) | - | 1003716..1004831 (-) | 1116 | WP_004748085.1 | FAD-binding oxidoreductase | - |
| DLE02_RS04865 (DLE02_00949) | hemB | 1004857..1005870 (-) | 1014 | WP_004748084.1 | porphobilinogen synthase | - |
| DLE02_RS04870 (DLE02_00950) | - | 1006013..1006510 (+) | 498 | WP_002156418.1 | thioesterase family protein | - |
| DLE02_RS04875 (DLE02_00951) | - | 1006780..1007931 (+) | 1152 | WP_004748081.1 | EmrA/EmrK family multidrug efflux transporter periplasmic adaptor subunit | - |
| DLE02_RS04880 (DLE02_00952) | - | 1007938..1009461 (+) | 1524 | WP_004748079.1 | DHA2 family efflux MFS transporter permease subunit | - |
| DLE02_RS04885 (DLE02_00953) | ggt | 1009765..1011750 (+) | 1986 | WP_004748076.1 | gamma-glutamyltransferase | - |
| DLE02_RS04895 (DLE02_00955) | - | 1012452..1013681 (+) | 1230 | WP_031999186.1 | tyrosine-type recombinase/integrase | - |
| DLE02_RS04900 (DLE02_00956) | - | 1013829..1014596 (+) | 768 | WP_000578618.1 | hypothetical protein | - |
| DLE02_RS04905 (DLE02_00957) | - | 1014806..1015021 (+) | 216 | WP_000153154.1 | hypothetical protein | - |
| DLE02_RS04910 (DLE02_00958) | - | 1015024..1015233 (+) | 210 | WP_001016479.1 | helix-turn-helix domain-containing protein | - |
| DLE02_RS04915 (DLE02_00959) | - | 1015230..1015784 (+) | 555 | WP_001988245.1 | BRO family protein | - |
| DLE02_RS04920 (DLE02_00960) | - | 1015777..1016145 (+) | 369 | WP_001046481.1 | hypothetical protein | - |
| DLE02_RS04925 (DLE02_00961) | - | 1016155..1016460 (+) | 306 | WP_258280804.1 | hypothetical protein | - |
| DLE02_RS04930 (DLE02_00963) | - | 1016582..1016860 (+) | 279 | WP_001064707.1 | hypothetical protein | - |
| DLE02_RS04935 (DLE02_00964) | - | 1016873..1019338 (+) | 2466 | WP_001022397.1 | DUF927 domain-containing protein | - |
| DLE02_RS04940 (DLE02_00965) | - | 1019672..1019788 (+) | 117 | WP_001992235.1 | single-stranded DNA-binding protein | - |
| DLE02_RS04945 (DLE02_00966) | - | 1020011..1021453 (+) | 1443 | WP_000003535.1 | hypothetical protein | - |
| DLE02_RS04950 | ssb | 1021435..1021536 (+) | 102 | WP_168713084.1 | single-stranded DNA-binding protein | Machinery gene |
Sequence
Protein
Download Length: 372 a.a. Molecular weight: 41896.10 Da Isoelectric Point: 6.6406
>NTDB_id=306488 DLE02_RS04815 WP_000347040.1 992738..993856(-) (pilU) [Acinetobacter baumannii strain LUH 6011]
MDFNDLLNLMVEKKSSDLFITDGVAPSMKINGQIVPISKNSLSGEVIGQLLQSIMSEKQRKEFAETRECNFAIMNREKTA
RFRVSAFQQRDMPGMVLRRIETKIPSIDDLQLPPVLKDLSMTKRGIIIFVGATGTGKSTSLASMISHRNHNSKGHIITIE
DPIEFIHEHAGCIITQREVGIDTDSFEIALKNTLRQAPDVILIGEIRSREVMDYAIGFAETGHLVLATMHANNANQALDR
IIHFFESDRHSQLYMDLSLNLKAMIAQQLIPTPDGNSRRAAIEILINSPLISDYIRKGEIHEIKDLMKRSRELGMQTFDQ
ALFDLYKAGQITYKDALKHADSPNDLRLTIKLADEGPDQLSDGKQHLTFDRQ
MDFNDLLNLMVEKKSSDLFITDGVAPSMKINGQIVPISKNSLSGEVIGQLLQSIMSEKQRKEFAETRECNFAIMNREKTA
RFRVSAFQQRDMPGMVLRRIETKIPSIDDLQLPPVLKDLSMTKRGIIIFVGATGTGKSTSLASMISHRNHNSKGHIITIE
DPIEFIHEHAGCIITQREVGIDTDSFEIALKNTLRQAPDVILIGEIRSREVMDYAIGFAETGHLVLATMHANNANQALDR
IIHFFESDRHSQLYMDLSLNLKAMIAQQLIPTPDGNSRRAAIEILINSPLISDYIRKGEIHEIKDLMKRSRELGMQTFDQ
ALFDLYKAGQITYKDALKHADSPNDLRLTIKLADEGPDQLSDGKQHLTFDRQ
Nucleotide
Download Length: 1119 bp
>NTDB_id=306488 DLE02_RS04815 WP_000347040.1 992738..993856(-) (pilU) [Acinetobacter baumannii strain LUH 6011]
ATGGATTTTAATGACTTGCTCAACCTGATGGTTGAAAAAAAATCATCGGATCTTTTTATTACAGATGGCGTTGCGCCCTC
TATGAAGATTAACGGACAAATTGTTCCAATTTCAAAAAATAGTCTTTCTGGGGAAGTGATTGGTCAACTGTTACAGTCCA
TCATGAGTGAAAAACAACGCAAAGAATTTGCAGAAACTCGTGAATGTAACTTTGCCATTATGAACCGTGAAAAAACGGCG
CGTTTTCGTGTCAGTGCTTTTCAGCAGCGCGACATGCCAGGCATGGTACTACGTCGTATTGAAACCAAGATTCCTTCAAT
TGATGACTTGCAGTTACCGCCTGTACTTAAAGATTTATCGATGACCAAACGCGGCATTATTATTTTTGTAGGCGCGACAG
GCACAGGTAAATCTACTTCATTGGCTTCAATGATCAGCCATCGTAACCATAACTCTAAGGGCCATATCATTACCATTGAA
GACCCGATTGAGTTTATTCACGAACATGCAGGCTGCATCATTACTCAGCGTGAGGTCGGGATCGATACCGACTCATTTGA
AATTGCCTTGAAAAATACATTACGACAAGCGCCGGATGTCATCTTAATTGGTGAGATTCGTTCTCGTGAAGTCATGGACT
ACGCGATTGGCTTTGCTGAAACAGGCCATCTTGTATTAGCTACCATGCACGCCAACAACGCCAACCAAGCACTCGACCGT
ATTATTCACTTTTTTGAAAGTGACCGTCATAGCCAGCTTTACATGGACTTGTCACTTAACTTAAAGGCAATGATTGCGCA
GCAGCTCATTCCAACACCAGATGGTAATTCACGCCGTGCAGCAATTGAGATTTTAATTAACTCACCATTAATTTCAGACT
ACATCCGTAAAGGTGAAATTCATGAAATTAAAGATTTGATGAAACGCTCACGTGAACTTGGTATGCAGACCTTTGACCAA
GCTTTATTTGATTTATATAAAGCTGGTCAAATTACCTACAAAGATGCACTTAAACATGCTGACTCACCGAACGATTTACG
TTTAACCATTAAACTTGCTGATGAGGGTCCTGATCAATTATCAGACGGGAAACAGCATTTAACTTTTGACCGCCAGTAA
ATGGATTTTAATGACTTGCTCAACCTGATGGTTGAAAAAAAATCATCGGATCTTTTTATTACAGATGGCGTTGCGCCCTC
TATGAAGATTAACGGACAAATTGTTCCAATTTCAAAAAATAGTCTTTCTGGGGAAGTGATTGGTCAACTGTTACAGTCCA
TCATGAGTGAAAAACAACGCAAAGAATTTGCAGAAACTCGTGAATGTAACTTTGCCATTATGAACCGTGAAAAAACGGCG
CGTTTTCGTGTCAGTGCTTTTCAGCAGCGCGACATGCCAGGCATGGTACTACGTCGTATTGAAACCAAGATTCCTTCAAT
TGATGACTTGCAGTTACCGCCTGTACTTAAAGATTTATCGATGACCAAACGCGGCATTATTATTTTTGTAGGCGCGACAG
GCACAGGTAAATCTACTTCATTGGCTTCAATGATCAGCCATCGTAACCATAACTCTAAGGGCCATATCATTACCATTGAA
GACCCGATTGAGTTTATTCACGAACATGCAGGCTGCATCATTACTCAGCGTGAGGTCGGGATCGATACCGACTCATTTGA
AATTGCCTTGAAAAATACATTACGACAAGCGCCGGATGTCATCTTAATTGGTGAGATTCGTTCTCGTGAAGTCATGGACT
ACGCGATTGGCTTTGCTGAAACAGGCCATCTTGTATTAGCTACCATGCACGCCAACAACGCCAACCAAGCACTCGACCGT
ATTATTCACTTTTTTGAAAGTGACCGTCATAGCCAGCTTTACATGGACTTGTCACTTAACTTAAAGGCAATGATTGCGCA
GCAGCTCATTCCAACACCAGATGGTAATTCACGCCGTGCAGCAATTGAGATTTTAATTAACTCACCATTAATTTCAGACT
ACATCCGTAAAGGTGAAATTCATGAAATTAAAGATTTGATGAAACGCTCACGTGAACTTGGTATGCAGACCTTTGACCAA
GCTTTATTTGATTTATATAAAGCTGGTCAAATTACCTACAAAGATGCACTTAAACATGCTGACTCACCGAACGATTTACG
TTTAACCATTAAACTTGCTGATGAGGGTCCTGATCAATTATCAGACGGGAAACAGCATTTAACTTTTGACCGCCAGTAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilU | Acinetobacter baylyi ADP1 |
75.926 |
100 |
0.772 |
| pilU | Pseudomonas stutzeri DSM 10701 |
69.022 |
98.925 |
0.683 |
| pilU | Vibrio cholerae strain A1552 |
52.973 |
99.462 |
0.527 |
| pilT | Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539 |
42.197 |
93.011 |
0.392 |